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The map label for this gene is yfeA

Identifier: 153947640

GI number: 153947640

Start: 1976390

End: 1977325

Strand: Reverse

Name: yfeA

Synonym: YpsIP31758_1705

Alternate gene names: 153947640

Gene position: 1977325-1976390 (Counterclockwise)

Preceding gene: 153947651

Following gene: 153950373

Centisome position: 41.86

GC content: 44.76

Gene sequence:

>936_bases
ATGATAGAACGACTAAACTCCCCTTTTCTACGGGCTGCAGCCTTGTTTACAATTGTCGCATTCTCATCGCTGATCAGTAC
CGCTGCTTTAGCAGAAAATAATCCCAGCGATACAGCCAAAAAATTCAAAGTTGTGACTACATTCACAATCATTCAGGATA
TTGCACAAAATATCGCCGGTGATGTTGCCGTGGTGGAGTCAATAACCAAGCCAGGCGCAGAGATTCATGACTATCAACCT
ACCCCACGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTTATGGAATGGCATGAATCTGGAGCGTTGGTTTGAGAA
GTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCGCAGGTATTACACCCCTGCCTATCCGTGAAGGCCCCT
ATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAATGCGCTAATATATATTGAGAATATCCGCAAAGCGTTA
GTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACGCGCAAGCCTATGCTGAAAAAATTAAGGCGCTAGATGC
TCCACTGCGTGAGCGTTTATCTCGTATTCCTGCGGAACAGCGTTGGTTAGTAACCAGTGAAGGGGCATTTAGTTATCTTG
CCAAAGACTATGGTTTTAAAGAGGTTTACTTATGGCCAATCAATGCAGAGCAACAAGGTATTCCGCAACAAGTTAGACAC
GTGATTGATATTATTCGCGAAAATAAAATTCCGGTGGTGTTTAGTGAGAGTACTATTTCCGACAAACCCGCCAAACAAGT
GAGTAAAGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTGATTCTCTGTCGGGCGAAAAAGGCCCGGTCCCCACTT
ACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGATTCGGTCAATGA

Upstream 100 bases:

>100_bases
AAGGAGGCTTGACTTCATCGCTAATGGTATTGATAATCATTTTCATTTGGAAAAAGAGAACATCGTGATGTTAATTAAGA
AAAAAAGTCCTTATCTCAAA

Downstream 100 bases:

>100_bases
GCCACCCTGTTTTTGTCCGCCCTGAGCTGGTAGTGGATAACGTCACTGTCACTTATAACAATGGTCATACTGCCATTTAT
GACGCCAGTTTTTCACTAAC

Product: chelated iron ABC transporter periplasmic protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQP
TPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKAL
VEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRH
VIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGFGQ

Sequences:

>Translated_311_residues
MIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQP
TPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKAL
VEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRH
VIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGFGQ
>Mature_311_residues
MIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQP
TPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKAL
VEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRH
VIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGFGQ

Specific function: Part of an ATP-driven transport system yfeABCD for chelated iron

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family

Homologues:

Organism=Escherichia coli, GI87081990, Length=251, Percent_Identity=22.7091633466135, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFEA_YERPE (Q56952)

Other databases:

- EMBL:   U50597
- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AH0297
- RefSeq:   NP_669213.1
- RefSeq:   NP_993556.1
- RefSeq:   YP_002347403.1
- ProteinModelPortal:   Q56952
- SMR:   Q56952
- GeneID:   1146844
- GeneID:   1175273
- GeneID:   2764801
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2439
- KEGG:   ypk:y1897
- KEGG:   ypm:YP_2227
- HOGENOM:   HBG731008
- OMA:   WPINAEE
- ProtClustDB:   CLSK889181
- BioCyc:   YPES187410:Y1897-MONOMER
- BioCyc:   YPES214092:YPO2439-MONOMER
- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128
- PRINTS:   PR00691
- PRINTS:   PR00690

Pfam domain/function: PF01297 SBP_bac_9

EC number: NA

Molecular weight: Translated: 34390; Mature: 34390

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVV
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
TAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAETYNRNAQAYAE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHCCCHHHHHH
KIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRH
HHHHHCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINM
HHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHH
TVDTIAKGFGQ
HHHHHHHHCCC
>Mature Secondary Structure
MIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVV
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
TAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAETYNRNAQAYAE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHCCCHHHHHH
KIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRH
HHHHHCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINM
HHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHH
TVDTIAKGFGQ
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430