Click here to switch to the map view.

The map label for this gene is intA [H]

Identifier: 153947376

GI number: 153947376

Start: 3264540

End: 3265070

Strand: Direct

Name: intA [H]

Synonym: YpsIP31758_2895

Alternate gene names: 153947376

Gene position: 3264540-3265070 (Clockwise)

Preceding gene: 153948403

Following gene: 153950328

Centisome position: 69.12

GC content: 46.7

Gene sequence:

>531_bases
ATGGCAAGGACAACACGCCCCCTCACCCATACCGAAGTACAAAAAGCAAAAGCCACCGACAAAGACCTAACTCTCCATGA
TGGTGATGGCTTATTTTTGTTAGTCAAAACTACCGGCAAGAAAATTTGGCGTTTCCGCTATCAGCTTCCCAACAGTAGTA
AACGCACTATGGTAAGCCTTGGCGCGTACCCTGCACTTTCTTTGGCTGATGCCAGAGAAGTACGAGCCGAGAAACTGGCC
ATGTTAGTGCGAGGGGTTGATCCCCAAGCAAGAGCTGATGAAGAAGCTGAAAAGCTCCAGATAGCGGAGGAAAGCATTTT
TGTGAATGTCGCCCGCAAATGGTTCGAGTTGAAAGAAAGCCACATTAGCGCAGCCCATGCGAAAAATATTTGGCGTTCTA
TTGAAAAAGACATCTTACCCAGCATCGAAAATATTCCCGTCCAAGAATTAAAAGCACGTACCCTGATTCAGGTATTAGAA
CCCATCAAAGCACGGGGAGCATTAGAGACTGACCTGCTCCCCATTGATTAA

Upstream 100 bases:

>100_bases
CCAAGGTGATCCGGCTGAAGCCAGAGACAATTGGTATACAAATTGGTATACGCTAAGATAGATACCAATGGACGTATACC
AATTAAGGGAAGAACCATAC

Downstream 100 bases:

>100_bases
CACACTCCGATGTTAGTAATGTCTTCATCAGCAACATGAGGACACCCCATGAAGAAACGTTTTTCCGACGAACAGATCAT
CAATATTCTCCGCGAGGCTG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLA
MLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKESHISAAHAKNIWRSIEKDILPSIENIPVQELKARTLIQVLE
PIKARGALETDLLPID

Sequences:

>Translated_176_residues
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLA
MLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKESHISAAHAKNIWRSIEKDILPSIENIPVQELKARTLIQVLE
PIKARGALETDLLPID
>Mature_175_residues
ARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMVSLGAYPALSLADAREVRAEKLAM
LVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKESHISAAHAKNIWRSIEKDILPSIENIPVQELKARTLIQVLEP
IKARGALETDLLPID

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=170, Percent_Identity=47.6470588235294, Blast_Score=179, Evalue=6e-47,
Organism=Escherichia coli, GI145693166, Length=164, Percent_Identity=32.3170731707317, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788690, Length=162, Percent_Identity=30.2469135802469, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 19862; Mature: 19731

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMVSL
CCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEECCCCCCCCEEEEE
GAYPALSLADAREVRAEKLAMLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKES
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HISAAHAKNIWRSIEKDILPSIENIPVQELKARTLIQVLEPIKARGALETDLLPID
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMVSL
CCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEECCCCCCCCEEEEE
GAYPALSLADAREVRAEKLAMLVRGVDPQARADEEAEKLQIAEESIFVNVARKWFELKES
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HISAAHAKNIWRSIEKDILPSIENIPVQELKARTLIQVLEPIKARGALETDLLPID
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]