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The map label for this gene is hofQ [H]

Identifier: 153947341

GI number: 153947341

Start: 4449429

End: 4450805

Strand: Reverse

Name: hofQ [H]

Synonym: YpsIP31758_3967

Alternate gene names: 153947341

Gene position: 4450805-4449429 (Counterclockwise)

Preceding gene: 153950525

Following gene: 153949876

Centisome position: 94.23

GC content: 47.86

Gene sequence:

>1377_bases
GTGCCATCACACAGCCGCTCCTCCAATAGCCATTTATCAGACAGCAAGTTATCAAACAGTGCTTCATCAAATAGTGCTTC
ATCAAATAGCACTTCATCAAATAGCACTTCATCAAACAGTGTCTTATCAAATAATGTCTCATCAAGTAATATCTCACCAA
ATAATGCCTCATCCAGTAATGCCTCATTACCGCGTACCCGCAGCGGGGGGCCAGTCACCCTGGAATTTCAGGATGCGCCG
GTCTCCGTCATCTTGCAGGCTCTGGCTGACTATCGGCAACTTAATCTGATCACGACTACCGGTGTGGGCGGCAATCTCAG
TTTGCGGTTGATTGAAGTGCCTTGGGAGCAGGCATTGGCGATCATTCTGCGGATGGGGCGTTTGAAAGCTGAGCGCGAGG
GGACCGTGATGATGGTCTTTACCGAACAGGAAATTCAAGAAAGGCAGCAGCGGACGAAACAGCAAGCTGCGCCAGAAGCA
CTGGCTAACCTGACATTGGCATTGCAATACGCGAATGCTGAACAGGTGGCTGACAGTTTGGATCCGCTGCAAGGTGGGCT
GCTTTCTCCATTGGGCAGTGTGGTGGCCGATAAGCGGACGAACACATTATTGATTCGCGATACGCCCGCTTCACTGGCAT
TGTTAAAAAACTGGCTGATTGAGATGGATTTACCGTTACAACAAGTACAGTTATCCGCGCATATTGTGACCATCAGCAGT
GAAGATTTACAAGAGCTGGGTGTGCGCTGGGGGATGGGGGAGGGCAAGGGAAACACCGCGCTCAGAATCAATGATTTTAA
TGTCAATTTGCCGTTGCCAAATAGCGCCGCGAGCGTGGGGTTTCATGTGGCCCGTATTGGTGGCCGCCTGCTGGAGCTTG
AGTTGAGTGCGTTGGAGCAAGAGAACCAGGTCGATATTATTGCCAGCCCACGCTTAATTACCTCACATCAACAAACCGCC
AGTATTAAACAAGGTTCTGATATTCCTTATACTGTCTCACGGGGTAAAAAAGAGGCAGCGGCCATTGAGTTCAAAGAAGC
GGTGTTGGGGATGGAGGTCACACCCAAAATTCTACGTAATGGCAAAATCATCCTAGACCTAAAAATTAGTCAAAATATGC
CCGGTATCACTATTAAACGCGGTGAGAGTGAAATGTTGCTAATAGATAAACAAGAAATTAAAACACAAGTTACTGTAAAC
GATGGCGAAACCATCGTGCTGGGCGGGATTTTCCAACAAAAAAAACGCCAGAGTGTTAATAAAGTCCCGTTACTGGCCGA
TATTCCACTATTAGGCGCGATGTTCAGGCAAGATACTCAACAGCAAAGTCGGCGGGAGTTAGTGATTTTCATTACGCCAA
AATTAATCAGTGCCTGA

Upstream 100 bases:

>100_bases
GACGAACTTCAATTTGGTGTATTTTCTTGGCAAAAATAAACACTTAAATCGCTCTAGAGGGTTGATTGGCTTATTAATTG
GGTGTCTCTTACTCATGGGC

Downstream 100 bases:

>100_bases
GCCTTGTAAGATGTCATTTTATGAAAACAGGGCAGTCTTGGTGACTTTCTGCAACTTTTTGTGTGATTGGAGGCTTCTAA
ATTTGACGCTGCGACAGATT

Product: outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MPSHSRSSNSHLSDSKLSNSASSNSASSNSTSSNSTSSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQDAP
VSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEA
LANLTLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISS
EDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTA
SIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVN
DGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Sequences:

>Translated_458_residues
MPSHSRSSNSHLSDSKLSNSASSNSASSNSTSSNSTSSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQDAP
VSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEA
LANLTLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISS
EDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTA
SIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVN
DGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
>Mature_457_residues
PSHSRSSNSHLSDSKLSNSASSNSASSNSTSSNSTSSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQDAPV
SVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEAL
ANLTLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSE
DLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTAS
IKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVND
GETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=405, Percent_Identity=47.6543209876543, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI87082242, Length=292, Percent_Identity=28.0821917808219, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 49594; Mature: 49463

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSHSRSSNSHLSDSKLSNSASSNSASSNSTSSNSTSSNSVLSNNVSSSNISPNNASSSN
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
ASLPRTRSGGPVTLEFQDAPVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALA
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHH
IILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANLTLALQYANAEQVADSL
HHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHH
DPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISS
CHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEECC
EDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQ
HHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHHCC
ENQVDIIASPRLITSHQQTASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRN
CCCEEEEECCCEEECCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHC
GKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQSVN
CCEEEEEEECCCCCCEEEECCCCCEEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCCCC
KVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCHHHCC
>Mature Secondary Structure 
PSHSRSSNSHLSDSKLSNSASSNSASSNSTSSNSTSSNSVLSNNVSSSNISPNNASSSN
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
ASLPRTRSGGPVTLEFQDAPVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALA
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHH
IILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANLTLALQYANAEQVADSL
HHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHH
DPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISS
CHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEECC
EDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQ
HHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHHCC
ENQVDIIASPRLITSHQQTASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRN
CCCEEEEECCCEEECCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHC
GKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQSVN
CCEEEEEEECCCCCCEEEECCCCCEEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCCCC
KVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]