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The map label for this gene is cysC [H]

Identifier: 153947128

GI number: 153947128

Start: 3711704

End: 3712345

Strand: Reverse

Name: cysC [H]

Synonym: YpsIP31758_3302

Alternate gene names: 153947128

Gene position: 3712345-3711704 (Counterclockwise)

Preceding gene: 153949941

Following gene: 153947709

Centisome position: 78.6

GC content: 50.0

Gene sequence:

>642_bases
GTGCCAGCCCATCAGTTAGATGACCATAACCAAGAAACGCGGTCAGACGATGAGAATATCGTCTGGCACCCCCATGCGAT
CACCCGACAGGATCGCGAACAACAGCACGGTCATCAGGGCGTAGTTCTTTGGTTTACCGGCCTGTCGGGTTCCGGGAAAT
CCACTCTGGCCGGTGCGCTGGAACAAGCGTTGTTCGCTCGCGGTGTCAGTACTTACTTACTGGATGGTGATAACGTGCGC
TATGGCCTCTGCCGCGATTTGGGCTTTTCTGACGCTGATCGTCGTGAAAATATCCGGCGGGTTGGCGAGGTGGCTAAACT
GATGGTTGATGCCGGTCTGGTGGTCTTGACGGCGTTTATTTCCCCTCATCGGGCTGAACGGAAAATGGTACAAGATATGC
TGGCATCGGGTCAGTTTATTGAGGTATTTGTCGATACGCCGTTAGCAATTTGTGAGGCCCGTGACCCGAAAGGCTTATAC
AAAAAAGCCCGTGCCGGAGAGCTTAAAAATTTTACAGGGATCGATTCAGTTTATGAATCGCCTGCGTCTCCTGATATCCA
TTTGCAGGGTGAACAATTAGTAACAAATTTGATTGAACAATTGTTAGACGTACTGCGTGGTAGAGCTATTATCAAATCCT
AA

Upstream 100 bases:

>100_bases
GAGAATCATGACTTCAGTACCTTTGAGCTGGAATTAAATGCCTTGGTTCGCCGTCATTTCCCACATTGGGGTGCGCGTGA
TCTGCTGGGGGGGAAATAGC

Downstream 100 bases:

>100_bases
ACGTATCCCCTTCGCACTTGACGCTACAGGGTCGTTCGCTGCAGGTATTCACTCGAATCACTGACGTTGTCAGCTAGCCG
TGATTTATTTGCAGCCTACC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPAHQLDDHNQETRSDDENIVWHPHAITRQDREQQHGHQGVVLWFTGLSGSGKSTLAGALEQALFARGVSTYLLDGDNVR
YGLCRDLGFSDADRRENIRRVGEVAKLMVDAGLVVLTAFISPHRAERKMVQDMLASGQFIEVFVDTPLAICEARDPKGLY
KKARAGELKNFTGIDSVYESPASPDIHLQGEQLVTNLIEQLLDVLRGRAIIKS

Sequences:

>Translated_213_residues
MPAHQLDDHNQETRSDDENIVWHPHAITRQDREQQHGHQGVVLWFTGLSGSGKSTLAGALEQALFARGVSTYLLDGDNVR
YGLCRDLGFSDADRRENIRRVGEVAKLMVDAGLVVLTAFISPHRAERKMVQDMLASGQFIEVFVDTPLAICEARDPKGLY
KKARAGELKNFTGIDSVYESPASPDIHLQGEQLVTNLIEQLLDVLRGRAIIKS
>Mature_212_residues
PAHQLDDHNQETRSDDENIVWHPHAITRQDREQQHGHQGVVLWFTGLSGSGKSTLAGALEQALFARGVSTYLLDGDNVRY
GLCRDLGFSDADRRENIRRVGEVAKLMVDAGLVVLTAFISPHRAERKMVQDMLASGQFIEVFVDTPLAICEARDPKGLYK
KARAGELKNFTGIDSVYESPASPDIHLQGEQLVTNLIEQLLDVLRGRAIIKS

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=200, Percent_Identity=49, Blast_Score=198, Evalue=3e-51,
Organism=Homo sapiens, GI62912492, Length=213, Percent_Identity=46.4788732394366, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI34447231, Length=213, Percent_Identity=46.4788732394366, Blast_Score=197, Evalue=8e-51,
Organism=Escherichia coli, GI1789107, Length=197, Percent_Identity=79.6954314720812, Blast_Score=330, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17542422, Length=200, Percent_Identity=48.5, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322852, Length=176, Percent_Identity=52.2727272727273, Blast_Score=200, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24667032, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24667028, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24667036, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24667040, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI116007838, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24667044, Length=174, Percent_Identity=50, Blast_Score=178, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23658; Mature: 23527

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAHQLDDHNQETRSDDENIVWHPHAITRQDREQQHGHQGVVLWFTGLSGSGKSTLAGAL
CCCCCCCCCCCHHCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
EQALFARGVSTYLLDGDNVRYGLCRDLGFSDADRRENIRRVGEVAKLMVDAGLVVLTAFI
HHHHHHCCCHHEEECCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPHRAERKMVQDMLASGQFIEVFVDTPLAICEARDPKGLYKKARAGELKNFTGIDSVYES
CCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCC
PASPDIHLQGEQLVTNLIEQLLDVLRGRAIIKS
CCCCCEEECHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure 
PAHQLDDHNQETRSDDENIVWHPHAITRQDREQQHGHQGVVLWFTGLSGSGKSTLAGAL
CCCCCCCCCCHHCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
EQALFARGVSTYLLDGDNVRYGLCRDLGFSDADRRENIRRVGEVAKLMVDAGLVVLTAFI
HHHHHHCCCHHEEECCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPHRAERKMVQDMLASGQFIEVFVDTPLAICEARDPKGLYKKARAGELKNFTGIDSVYES
CCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCC
PASPDIHLQGEQLVTNLIEQLLDVLRGRAIIKS
CCCCCEEECHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]