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The map label for this gene is comEC [H]

Identifier: 153947078

GI number: 153947078

Start: 2922006

End: 2924297

Strand: Reverse

Name: comEC [H]

Synonym: YpsIP31758_2578

Alternate gene names: 153947078

Gene position: 2924297-2922006 (Counterclockwise)

Preceding gene: 153947721

Following gene: 153949531

Centisome position: 61.91

GC content: 47.16

Gene sequence:

>2292_bases
ATGGTTTTTATCGCGTTATCAACAGATCGGGTCGCCGCTGCTGTCATTGTCGGGATCTTGCCTCTTATTTTTCTGCATCA
ACTACCAGGGCCCACTATCATTGGTTCTCTATTAGCCCTAAGTGCATTTTTGTGGTTAAGCCGCAATCGTTACTGCCAAT
TTTTAGCGCTGATTGTGATTAGCTTCCTGTGGGGGGTTTGGCATAGCAATGAGATACTGATGCAAACAGAAGCATTAACC
CAGGGGGATCAGCAGATAGTTGCGACAATAAACAGTTCATCTCTTTCATGGGATGACGGCCAGAAAGTTGTGATAAGTAT
TCAGAAAATTAATGAAAAACGGGTTTTCCCTCCAATAGCAGTCAACGTTAAGTGGCCAGAACGGTTGGATCAATACTGTG
CAGGGCAACGCTGGGCGTTTAGGTTACGTATGAGGGCAGTACATAGCGTACTGAATGAGGGCGGGTTTGACAGTCAGCGC
TGGGCTATTGCTAACCGACGTCCACTACAAGGGCGCATCATTGAGGCTAAATTACTGGATGCAGAGTGTAATTTTCGTCA
GCAAATTATCAGTAGCATAGAGCAGCAACTGGTGGGATATGATCAGCGGCGGATCATGCTAGCACTGGCCTTTGGTGAAA
GATCACAACTGAACAAAGAAGAGTGGTCACTCTTACGCTACACCGGCACTGCGCACCTGATGGCGATTTCCGGTTTACAT
ATTGCACTGGCGGCCTTATTTGGTGGGATGCTTGCCCGATTAGTACAGCTCCTTTTTCCTGTCAGTTGGATTGGGCCTTT
GCTACCGCTACTGATTGGCTGGCTGATTGCTATGATTTATGTCTGGCTGGCAGGAGCAAACTCACCAGCAATCCGGGCGG
CCATTGCGTTAACGCTGTGGCTGCTGCTACGTTTGTTCGGTATTTTATGTAGCCCATGGCAGGTGTGGAGGTGGGCTTTG
GGGCTAATTTTAGTCAGCGACCCGCTAGCCGTATTATCAGACAGCTTTTGGCTCTCCTGCCTGGCGGTATTTAGCCTGAT
ATGTTGGTTTCACTTGGCCCCTGTTTCTTCTCGTTTCATTACTGGTTGGTATGGCTTGGTTATCCGTTGGTTTCATTTGC
AGTTTGGTATGATGCTACTGCTGATGCCGTTACAGATAGGGTTATTCCACGGTATAAGTTTATTTTCTATACCCGCCAAT
CTGTGGGCGGTCCCAATAGTCTCATTGTTCACCGTACCCTGCGTATTATTAGCATTGGCTTTAGCATTGCTCCCTGCTGT
TGCTGATATATTTTGGTTCTTGGCTGATATCTCGTTGACTGTGGTGCTATTCCCGCTCAATCAGCTAAAAGAAGGCTGGT
TACACACTGGCATGGCTTCTGTTGCGATCGGTTATGGTGGTTGGCTGGCATTATTTATCTGGCGCTTTCAATGGTGGCGC
AGTCATCCTCTTGGTGTCATTGTGCTGTGTATGAACATGGTATTACTGACTCAACGGCGTGATGAGTATCACTGGCGTGT
GGATATGCTGGATATCGGGCATGGTCTGGCTGTGGTGATTGAGCGTGAGGGGAAAGCCATTATCTATGACACTGGCAATC
ATTGGCCTACAGGTAATATGGCCGCTATTGTCGTTTTACCGCTCCTTAAATGGCGTGGCATTACTGTTGAACAGATTATC
CTTAGCCATGACCATCAGGACCATACTGGCGGTTTGGCTGTACTCTTGGATGCTTTTCCGCAGGCAACGGTACGTGCGCC
TTTCTCTGTAAAAAACGTAGCCAATACTCTGCCTTGTAAACAGGGGGAGAGATGGCAGTGGCAAGGTTTAGATTTTGACG
TGTTATGGCCGAAAGAACAGGTGGTTAATGCTCAGAATAATGACTCATGTGTCATTCGCATTAATGATGGTAAACATAGT
GTATTGTTGACCGGGGATCTTGAGTCCCAAGGAGAACGGCAGTTGGTGAACGATATCCGGGGAGAATTAACATCAACGGT
GCTGCAAGTGCCCCATCACGGTAGTAATACTTCTTCAACCGCGCCTTTTCTACGGGCAGTTAGCCCAGAATTGGCCCTCG
CTTCTGTTGCTCGTTATAACCAATGGCGACTACCTGCGAAAAAAGTGATCAATCGCTATCAAAAAAATGGCATTATTTGG
CGTGATACATCAGTATCAGGGCAATTAAGTGTATATTTTCACTGCGATACTTGGTTCGTTAAAGGCTATCGGGAACAATT
AAAGCCACGTTGGTATCACCAGCGGTTTGGCGTTAGAGGTCATAATGAGTAG

Upstream 100 bases:

>100_bases
TCTTTGGCCCCAATGTTGAGAATCAACCTATTCCAAATGGCGTAAACAGCCAGACGACAGAGATGAATAGCAATGAGGCT
ATTCAAGAGTAAAAACAGGG

Downstream 100 bases:

>100_bases
AATGGGCCGCTATTTCTTATGGTGTTGGTATTTGCATGATGAATGATAAAGATCTATCTACTTGGCAGACCTTTCGTCGC
CTATGGCCGACGATCTCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MVFIALSTDRVAAAVIVGILPLIFLHQLPGPTIIGSLLALSAFLWLSRNRYCQFLALIVISFLWGVWHSNEILMQTEALT
QGDQQIVATINSSSLSWDDGQKVVISIQKINEKRVFPPIAVNVKWPERLDQYCAGQRWAFRLRMRAVHSVLNEGGFDSQR
WAIANRRPLQGRIIEAKLLDAECNFRQQIISSIEQQLVGYDQRRIMLALAFGERSQLNKEEWSLLRYTGTAHLMAISGLH
IALAALFGGMLARLVQLLFPVSWIGPLLPLLIGWLIAMIYVWLAGANSPAIRAAIALTLWLLLRLFGILCSPWQVWRWAL
GLILVSDPLAVLSDSFWLSCLAVFSLICWFHLAPVSSRFITGWYGLVIRWFHLQFGMMLLLMPLQIGLFHGISLFSIPAN
LWAVPIVSLFTVPCVLLALALALLPAVADIFWFLADISLTVVLFPLNQLKEGWLHTGMASVAIGYGGWLALFIWRFQWWR
SHPLGVIVLCMNMVLLTQRRDEYHWRVDMLDIGHGLAVVIEREGKAIIYDTGNHWPTGNMAAIVVLPLLKWRGITVEQII
LSHDHQDHTGGLAVLLDAFPQATVRAPFSVKNVANTLPCKQGERWQWQGLDFDVLWPKEQVVNAQNNDSCVIRINDGKHS
VLLTGDLESQGERQLVNDIRGELTSTVLQVPHHGSNTSSTAPFLRAVSPELALASVARYNQWRLPAKKVINRYQKNGIIW
RDTSVSGQLSVYFHCDTWFVKGYREQLKPRWYHQRFGVRGHNE

Sequences:

>Translated_763_residues
MVFIALSTDRVAAAVIVGILPLIFLHQLPGPTIIGSLLALSAFLWLSRNRYCQFLALIVISFLWGVWHSNEILMQTEALT
QGDQQIVATINSSSLSWDDGQKVVISIQKINEKRVFPPIAVNVKWPERLDQYCAGQRWAFRLRMRAVHSVLNEGGFDSQR
WAIANRRPLQGRIIEAKLLDAECNFRQQIISSIEQQLVGYDQRRIMLALAFGERSQLNKEEWSLLRYTGTAHLMAISGLH
IALAALFGGMLARLVQLLFPVSWIGPLLPLLIGWLIAMIYVWLAGANSPAIRAAIALTLWLLLRLFGILCSPWQVWRWAL
GLILVSDPLAVLSDSFWLSCLAVFSLICWFHLAPVSSRFITGWYGLVIRWFHLQFGMMLLLMPLQIGLFHGISLFSIPAN
LWAVPIVSLFTVPCVLLALALALLPAVADIFWFLADISLTVVLFPLNQLKEGWLHTGMASVAIGYGGWLALFIWRFQWWR
SHPLGVIVLCMNMVLLTQRRDEYHWRVDMLDIGHGLAVVIEREGKAIIYDTGNHWPTGNMAAIVVLPLLKWRGITVEQII
LSHDHQDHTGGLAVLLDAFPQATVRAPFSVKNVANTLPCKQGERWQWQGLDFDVLWPKEQVVNAQNNDSCVIRINDGKHS
VLLTGDLESQGERQLVNDIRGELTSTVLQVPHHGSNTSSTAPFLRAVSPELALASVARYNQWRLPAKKVINRYQKNGIIW
RDTSVSGQLSVYFHCDTWFVKGYREQLKPRWYHQRFGVRGHNE
>Mature_763_residues
MVFIALSTDRVAAAVIVGILPLIFLHQLPGPTIIGSLLALSAFLWLSRNRYCQFLALIVISFLWGVWHSNEILMQTEALT
QGDQQIVATINSSSLSWDDGQKVVISIQKINEKRVFPPIAVNVKWPERLDQYCAGQRWAFRLRMRAVHSVLNEGGFDSQR
WAIANRRPLQGRIIEAKLLDAECNFRQQIISSIEQQLVGYDQRRIMLALAFGERSQLNKEEWSLLRYTGTAHLMAISGLH
IALAALFGGMLARLVQLLFPVSWIGPLLPLLIGWLIAMIYVWLAGANSPAIRAAIALTLWLLLRLFGILCSPWQVWRWAL
GLILVSDPLAVLSDSFWLSCLAVFSLICWFHLAPVSSRFITGWYGLVIRWFHLQFGMMLLLMPLQIGLFHGISLFSIPAN
LWAVPIVSLFTVPCVLLALALALLPAVADIFWFLADISLTVVLFPLNQLKEGWLHTGMASVAIGYGGWLALFIWRFQWWR
SHPLGVIVLCMNMVLLTQRRDEYHWRVDMLDIGHGLAVVIEREGKAIIYDTGNHWPTGNMAAIVVLPLLKWRGITVEQII
LSHDHQDHTGGLAVLLDAFPQATVRAPFSVKNVANTLPCKQGERWQWQGLDFDVLWPKEQVVNAQNNDSCVIRINDGKHS
VLLTGDLESQGERQLVNDIRGELTSTVLQVPHHGSNTSSTAPFLRAVSPELALASVARYNQWRLPAKKVINRYQKNGIIW
RDTSVSGQLSVYFHCDTWFVKGYREQLKPRWYHQRFGVRGHNE

Specific function: Unknown

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae Rec2 [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=764, Percent_Identity=41.2303664921466, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 86326; Mature: 86326

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFIALSTDRVAAAVIVGILPLIFLHQLPGPTIIGSLLALSAFLWLSRNRYCQFLALIVI
CEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SFLWGVWHSNEILMQTEALTQGDQQIVATINSSSLSWDDGQKVVISIQKINEKRVFPPIA
HHHHHHHCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEE
VNVKWPERLDQYCAGQRWAFRLRMRAVHSVLNEGGFDSQRWAIANRRPLQGRIIEAKLLD
EEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEEEC
AECNFRQQIISSIEQQLVGYDQRRIMLALAFGERSQLNKEEWSLLRYTGTAHLMAISGLH
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHCCHHHHHEEEECCCCHHHHHHHHH
IALAALFGGMLARLVQLLFPVSWIGPLLPLLIGWLIAMIYVWLAGANSPAIRAAIALTLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LLLRLFGILCSPWQVWRWALGLILVSDPLAVLSDSFWLSCLAVFSLICWFHLAPVSSRFI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWYGLVIRWFHLQFGMMLLLMPLQIGLFHGISLFSIPANLWAVPIVSLFTVPCVLLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHH
LALLPAVADIFWFLADISLTVVLFPLNQLKEGWLHTGMASVAIGYGGWLALFIWRFQWWR
HHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHH
SHPLGVIVLCMNMVLLTQRRDEYHWRVDMLDIGHGLAVVIEREGKAIIYDTGNHWPTGNM
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCH
AAIVVLPLLKWRGITVEQIILSHDHQDHTGGLAVLLDAFPQATVRAPFSVKNVANTLPCK
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
QGERWQWQGLDFDVLWPKEQVVNAQNNDSCVIRINDGKHSVLLTGDLESQGERQLVNDIR
CCCCEEECCCCEEEECCHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
GELTSTVLQVPHHGSNTSSTAPFLRAVSPELALASVARYNQWRLPAKKVINRYQKNGIIW
HHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEE
RDTSVSGQLSVYFHCDTWFVKGYREQLKPRWYHQRFGVRGHNE
EECCCCCEEEEEEEECHHHHHHHHHHCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MVFIALSTDRVAAAVIVGILPLIFLHQLPGPTIIGSLLALSAFLWLSRNRYCQFLALIVI
CEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SFLWGVWHSNEILMQTEALTQGDQQIVATINSSSLSWDDGQKVVISIQKINEKRVFPPIA
HHHHHHHCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEE
VNVKWPERLDQYCAGQRWAFRLRMRAVHSVLNEGGFDSQRWAIANRRPLQGRIIEAKLLD
EEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEEEC
AECNFRQQIISSIEQQLVGYDQRRIMLALAFGERSQLNKEEWSLLRYTGTAHLMAISGLH
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHCCHHHHHEEEECCCCHHHHHHHHH
IALAALFGGMLARLVQLLFPVSWIGPLLPLLIGWLIAMIYVWLAGANSPAIRAAIALTLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LLLRLFGILCSPWQVWRWALGLILVSDPLAVLSDSFWLSCLAVFSLICWFHLAPVSSRFI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWYGLVIRWFHLQFGMMLLLMPLQIGLFHGISLFSIPANLWAVPIVSLFTVPCVLLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHH
LALLPAVADIFWFLADISLTVVLFPLNQLKEGWLHTGMASVAIGYGGWLALFIWRFQWWR
HHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHH
SHPLGVIVLCMNMVLLTQRRDEYHWRVDMLDIGHGLAVVIEREGKAIIYDTGNHWPTGNM
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCH
AAIVVLPLLKWRGITVEQIILSHDHQDHTGGLAVLLDAFPQATVRAPFSVKNVANTLPCK
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
QGERWQWQGLDFDVLWPKEQVVNAQNNDSCVIRINDGKHSVLLTGDLESQGERQLVNDIR
CCCCEEECCCCEEEECCHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
GELTSTVLQVPHHGSNTSSTAPFLRAVSPELALASVARYNQWRLPAKKVINRYQKNGIIW
HHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEE
RDTSVSGQLSVYFHCDTWFVKGYREQLKPRWYHQRFGVRGHNE
EECCCCCEEEEEEEECHHHHHHHHHHCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 8094880 [H]