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The map label for this gene is mdtA

Identifier: 153947015

GI number: 153947015

Start: 1430918

End: 1432252

Strand: Reverse

Name: mdtA

Synonym: YpsIP31758_1215

Alternate gene names: 153947015

Gene position: 1432252-1430918 (Counterclockwise)

Preceding gene: 153950164

Following gene: 153948688

Centisome position: 30.32

GC content: 54.38

Gene sequence:

>1335_bases
ATGAAATCTCAATCCAAACGCACTTCCCGATTATTCGTATTCGTGGGGGGAGTGGTGGCGATCATTATTGCGGTGCTTAG
TTGGCGCTACTTCGGTACCGGCTCCGATAACAATACGTCAGGTGCTCAGCAGAGTGCCCGTGGTCAGGACACTAGCCATG
GTGGCCGTCGTAATACACCGCTGGCACCGGTGCAGGCCGCAACCGCAACCGAGCAGGAAGTGCCACGTTATCTCACTGGC
TTAGGGACGGTCATTGCCGCCAATACTGTCACGGTAACCAGCCGAGTGGATGGTGAATTGATGGCCCTTCATTTCACTGA
AGGGCAGCAGGTTAAGGCTGGCGATTTACTGGCAGAGATCGATCCCCGCCCTTACGAAGTCCAACTGACGCAGGCTCAGG
GGCAGTTGGCCAAAGATCAGGCCACGCTGGATAACGCCCGTCGTGATCTGGCCCGTTATCAGAAATTGTCCAAAACTGGC
CTGATTTCGCAACAGGAACTGGATACGCAATCTTCGCTGGTACGCCAGAGCGAGGGCAGTGTGAAAGCCGATCAGGGCGC
TATCGACAGCGCCAAATTGCAACTGACGTATAGCCGTATTACCGCGCCTATCTCCGGTAGAGTGGGCCTGAAACAAGTGG
ATGTCGGCAATTACATTACCAGCGGCACGGCCACACCGATTGTGGTGATCACCCAGACACATCCCGTTGATGTGGTCTTT
ACCCTGCCAGAAAGCGATATTCCCGCCATTATACAAGCACAGAAAAATGCGGAGAAGACTCACGCCATCGTGCCCGTGGA
AGCGTGGGATCGGACGAATAAACAGATGCTGGCACAGGGCTACCTGCTCAGTATTGATAACCAGATTGATACCACGACGG
GCACCATTAAACTGAAGGCCCGCTTTAATAATGAAGATGATGTGCTGTTCCCTAATCAGTTTGTTAACGCCCGTATCAAG
GTCGATTTGCTGCAAAATGCTGTCGTGGTGCCCACCGCAGCGGTACAAATGGGCAGCGAAGGTAACTTTGTCTGGACGTT
AGATGATGCAAATAAAGTCAGCAAACATCTGGTCACCACCGGGATTCAGAATAGCCAACAAGTGGTTATCGACGCAGGCC
TGAACGCTGGGCAACGCGTGGTCACGGATGGTATTGATCGCCTGACCGAGGGGGTACAGGTTGAAGTGGTGACACCACGC
AGCGCCAATACTGATGCTAATCCAGCCAGTGCAGAGAAAGCGGCTGCAGAAGCAGAAGGCAGCACCCCGCATCAAGGCCG
AGGGCGTCCGGCCAATGCGCCTGCACGTAGCACCACGGCTGCGGAGAAATCCTGA

Upstream 100 bases:

>100_bases
TATCCGGTAATTGCCCGTTAAACTAGTAGCATATCCGAAAACTCAGAGACTGCGCCCATGTGGTGCAGGTAGCCACGATA
AAAAAGGACGCTTCGCCATC

Downstream 100 bases:

>100_bases
TGCAAGTGATGCCTCCAACACCCGGTGGCGGGCCGTCACGGCTGTTTATTCTGCGCCCGGTCGCCACCACATTATTTATG
ATCGCGATTTTACTGGCCGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKSQSKRTSRLFVFVGGVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDANPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS

Sequences:

>Translated_444_residues
MKSQSKRTSRLFVFVGGVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDANPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS
>Mature_444_residues
MKSQSKRTSRLFVFVGGVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDANPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family

Homologues:

Organism=Escherichia coli, GI87082036, Length=390, Percent_Identity=66.6666666666667, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1789665, Length=362, Percent_Identity=30.939226519337, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789929, Length=327, Percent_Identity=28.4403669724771, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786668, Length=409, Percent_Identity=30.3178484107579, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081951, Length=166, Percent_Identity=34.3373493975904, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081796, Length=345, Percent_Identity=25.5072463768116, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790519, Length=235, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTA_YERP3 (A7FG18)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400196.1
- ProteinModelPortal:   A7FG18
- SMR:   A7FG18
- STRING:   A7FG18
- GeneID:   5385078
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1215
- NMPDR:   fig|349747.3.peg.1331
- eggNOG:   COG0845
- HOGENOM:   HBG742930
- OMA:   SFRETFQ
- ProtClustDB:   PRK11556
- BioCyc:   YPSE349747:YPSIP31758_1215-MONOMER
- HAMAP:   MF_01422
- InterPro:   IPR022824
- InterPro:   IPR006143
- TIGRFAMs:   TIGR01730

Pfam domain/function: PF00529 HlyD

EC number: NA

Molecular weight: Translated: 47473; Mature: 47473

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSQSKRTSRLFVFVGGVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTP
CCCCCCCCCEEEEEHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCC
LAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEI
CCCCHHHCCCHHHHHHHHHHHHHEEEECEEEEEEECCCEEEEEEECCCCEEECCCCCEEC
DPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCC
VKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
CCCCCCCCCCEEEEEEEHHEECCCCCCCCCEEEECCCEEECCCCCEEEEEEECCCEEEEE
TLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKA
ECCCCCCCHHEEECCCCCCCEEEEEEHHCCCCCHHHHHCCEEEEECCCCCCCCEEEEEEE
RFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTT
EECCCCCEECCHHHCCCEEEEEECCCEEEEEEHHEEECCCCCEEEEECCHHHHHHHHHHH
GIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDANPASAEKAAAEAEG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCC
STPHQGRGRPANAPARSTTAAEKS
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSQSKRTSRLFVFVGGVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTP
CCCCCCCCCEEEEEHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCC
LAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEI
CCCCHHHCCCHHHHHHHHHHHHHEEEECEEEEEEECCCEEEEEEECCCCEEECCCCCEEC
DPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCC
VKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
CCCCCCCCCCEEEEEEEHHEECCCCCCCCCEEEECCCEEECCCCCEEEEEEECCCEEEEE
TLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKA
ECCCCCCCHHEEECCCCCCCEEEEEEHHCCCCCHHHHHCCEEEEECCCCCCCCEEEEEEE
RFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTT
EECCCCCEECCHHHCCCEEEEEECCCEEEEEEHHEEECCCCCEEEEECCHHHHHHHHHHH
GIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDANPASAEKAAAEAEG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCC
STPHQGRGRPANAPARSTTAAEKS
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA