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The map label for this gene is yeeO [H]

Identifier: 153946973

GI number: 153946973

Start: 2708882

End: 2710312

Strand: Reverse

Name: yeeO [H]

Synonym: YpsIP31758_2407

Alternate gene names: 153946973

Gene position: 2710312-2708882 (Counterclockwise)

Preceding gene: 153950600

Following gene: 153948397

Centisome position: 57.38

GC content: 50.8

Gene sequence:

>1431_bases
ATGCAAATGAACAGGGTTTCAGAGGCCGTTAAGTTGAAAATCTTCCGCGAAAGCGTGTGGTATAAGAAGCGAAAATCATC
TCGGGTACTCTTTTGGCGTGAGATCACACCGCTGGCCTTTCCGTTGTTTATTGAAGGTTTGTGCGTACTGCTGATGGGGG
TATTTAGTACTCTGCTGGTGAGTTGGTTGGGTAAAGAAGCGATGGCAGCGGTGGGGCTAGCCGACAGTTTCAATATGCTG
ATTGCGGCTTTTTTTGCCTCCGTGGCATTAGGGACCTCGGTCGTTGTGGCCTTCAGTCTGGGCCAACGCAAACGCCAGCA
GGCGCAAACTGCCGCCCGACAATCCATGACATTGCTGGTATTAATCTCCCTGTTATTAGTTGTCTTGGTTCATTTTTCAG
GCCAGACCATTATTGATTTAATGGCTAACCAGGCAGACCCCTCGGTTAAAGCAATGGCCCTGACCTATCTGCATTTCACT
GTCTGGAATTACCCTGCGATGGCGATAACCTTGGTGGGGTGCGGTGCGTTACGTGGTGCGGGCAATACGCGTTTGCCGAT
GCTTATTAACATTGGCATGAACATTCTTAACATTGTCATTAGCAGTATATTAATTTATGGCCTCTTTAATTGGCAGGGAC
TGGGTTTTATCGGTGCCGGTATTGGCATCACATTGGCCCGCTCTGCAGGCGCACTGGTGGTGGTCGTGCTGCTGATTTAC
GGCGCGAATAATACGTTGCGGATCCCCTTCAAAGCCTATTTCATGCCTTTTACCTCGGCCATTATGTTTGAGGTGCTGAG
CATTGGTATTCCGGCGAGTGTTGAGTCAGTTATGTTCAATATTGGCAAGTTAATCACTCAACGGTTTGTTGCCGGCATGG
GGACCGACGTGATCGCGGGTAACTTTATTGCCTTTTCAATTGTGGCGATAATCAATCTGCCCGGTAATGCGCTGGGGTAC
ACCTCAACCATTATTATTGGTACCCGGCTGGGCAAGGGGCAAATTTTGCAACCTATTCGGCAGATAAAACATATCTTTTG
GCTATCGACGCTTGGGGTCTGCTTTATTGCATTGCTGTCCATTCCCAGTGCGGGTTTTCTGGCCTCGCTGTATACCGATG
ATCCGGCAGTTATCACGGTGGTGAAGCATTTGATCTGGATGAATGCGTTATTTATGCCGATTTGGGCGGCGTCTTGGGTC
TTACCTGCCGGCTTGAAAGGCGCTAAGGATGCCAGTTACACCATGTGGGTTGCCCTGGCCGGGATGTGGGGCTGTCGCAT
TATTGCTGGCTACATTCTGGGGGTAACGCTAGGGTTTGGCGTGACGGGGGTATGGATGGGGATGTTCCTGGATTGGATGG
TCCGGGGGGGGTTGTTTTATCGCCGCATGTCCACGGGCCGTTGGTTATGGCGCTACCGGCCCAGCGTCTGA

Upstream 100 bases:

>100_bases
TTTTTTGAAACGCGCAGCGGGTTAACATATCTAGCGGGAAATCAACATTGTAAATCGGCGCATTGGGATATTTCACCATA
GTGGTGGAAAGCGCGGATGG

Downstream 100 bases:

>100_bases
GAATATAAGCCGGTGTCCCCCATCGAATTACTTCACACTCTGCGGTGCCACGTGGTGGGCAAACAGCATAATGACGCCAG
AGATAAAGCAGGGGATGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNML
IAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFT
VWNYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIY
GANNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGY
TSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWV
LPAGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGGLFYRRMSTGRWLWRYRPSV

Sequences:

>Translated_476_residues
MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNML
IAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFT
VWNYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIY
GANNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGY
TSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWV
LPAGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGGLFYRRMSTGRWLWRYRPSV
>Mature_476_residues
MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNML
IAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFT
VWNYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIY
GANNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGY
TSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWV
LPAGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGGLFYRRMSTGRWLWRYRPSV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=472, Percent_Identity=63.135593220339, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI48994890, Length=427, Percent_Identity=25.9953161592506, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52040; Mature: 52040

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SWLGKEAMAAVGLADSFNMLIAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLV
HHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVWNYPAMAITLVGCGALRGA
HHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIY
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHEECCCCCHHHHHHHHHH
GANNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAG
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NFIAFSIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLS
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLPAGLKGAKDASYTMWVALA
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGGLFYRRMSTGRWLWRYRPSV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEECCCC
>Mature Secondary Structure
MQMNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SWLGKEAMAAVGLADSFNMLIAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLV
HHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVWNYPAMAITLVGCGALRGA
HHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIY
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHEECCCCCHHHHHHHHHH
GANNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAG
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NFIAFSIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLS
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLPAGLKGAKDASYTMWVALA
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGGLFYRRMSTGRWLWRYRPSV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]