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The map label for this gene is hydC [H]

Identifier: 153952637

GI number: 153952637

Start: 408745

End: 409461

Strand: Direct

Name: hydC [H]

Synonym: JJD26997_0460

Alternate gene names: 153952637

Gene position: 408745-409461 (Clockwise)

Preceding gene: 153951533

Following gene: 153952404

Centisome position: 22.15

GC content: 32.36

Gene sequence:

>717_bases
ATGTCAATTTATAAGGAGGCTTTCATGCAAAATAAAGAAGAAAAATTGCAAAGAAAAGCTGAATATGAATTTAGCATAGG
GTTACGTTTAACACACTGGGTAAGAGCTGTGGCTATAGTGATTCTTATTGGCACAGGGTATTATCTTTCTTATGTGTTTC
AAAGCCCTATTAGTAACGGTGAACCTGTTAATTTTATGCAAGCAAAATACCGCTTAGTGCATCAAGCGGTAGGTTTTGTT
TTAATCGCTTGTATTGTTTTTAAAGTGTATTTGTTTTTTTGCGACAAAATAAGTGCAAAAGAACGCAGAAGTGTATGGGA
TATTTTTAATATCAAATTATGGATAGAACAAGTAAAATTTTACATTTTCTTAGGAAAACATCCGCATTTAAAAGGAGTTT
ATAATCCTTTGCAATTTGTAACTTATTTTTTCTTTTATCTTGTGATATTAGGCATCATTTTAACAGGACTTATTCTCTAT
ACTCATACTTATCATGAGGGCTTAGGTGGGTTTTTATATCATATTTTAAGACCGCTTGAAGCTGCAATGGGCGGCTTGGC
TGACGTAAGAACTTATCATAGAATTTTGATGTGGGTGATTATGATTTTTGTACCAGTACATATTTACATGGCGATTTTTA
ACGCAGTAAAAGGTAAAGATGGTGCTATGGATGCTATTATTAGCGGATATAAATATGTAAAAGAAGAAAAGCATTGA

Upstream 100 bases:

>100_bases
CTTGAAATCATTAGAAAAATTCACTCTTATGATCCTTGTATCGCGTGTGCGGTGCATGTAATGGATACTAAGGGTAATAA
TCTAAGCGAATATAAAGTGA

Downstream 100 bases:

>100_bases
AATTCTTAGTCCTTGGAATAGGCAATATCATGTTTGCGGATGAAGGCTTAGGCGTTCATCTTTGCAAACAACTTGAAAAA
AACTACAAATTTAGTCATCC

Product: quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit

Products: oxidized ferredoxin; H2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSIYKEAFMQNKEEKLQRKAEYEFSIGLRLTHWVRAVAIVILIGTGYYLSYVFQSPISNGEPVNFMQAKYRLVHQAVGFV
LIACIVFKVYLFFCDKISAKERRSVWDIFNIKLWIEQVKFYIFLGKHPHLKGVYNPLQFVTYFFFYLVILGIILTGLILY
THTYHEGLGGFLYHILRPLEAAMGGLADVRTYHRILMWVIMIFVPVHIYMAIFNAVKGKDGAMDAIISGYKYVKEEKH

Sequences:

>Translated_238_residues
MSIYKEAFMQNKEEKLQRKAEYEFSIGLRLTHWVRAVAIVILIGTGYYLSYVFQSPISNGEPVNFMQAKYRLVHQAVGFV
LIACIVFKVYLFFCDKISAKERRSVWDIFNIKLWIEQVKFYIFLGKHPHLKGVYNPLQFVTYFFFYLVILGIILTGLILY
THTYHEGLGGFLYHILRPLEAAMGGLADVRTYHRILMWVIMIFVPVHIYMAIFNAVKGKDGAMDAIISGYKYVKEEKH
>Mature_237_residues
SIYKEAFMQNKEEKLQRKAEYEFSIGLRLTHWVRAVAIVILIGTGYYLSYVFQSPISNGEPVNFMQAKYRLVHQAVGFVL
IACIVFKVYLFFCDKISAKERRSVWDIFNIKLWIEQVKFYIFLGKHPHLKGVYNPLQFVTYFFFYLVILGIILTGLILYT
HTYHEGLGGFLYHILRPLEAAMGGLADVRTYHRILMWVIMIFVPVHIYMAIFNAVKGKDGAMDAIISGYKYVKEEKH

Specific function: B-type cytochrome that interacts with quinones and anchor the hydrogenase to the membrane [H]

COG id: COG1969

COG function: function code C; Ni,Fe-hydrogenase I cytochrome b subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupC/hyaC/hydC family [H]

Homologues:

Organism=Escherichia coli, GI1787208, Length=232, Percent_Identity=26.7241379310345, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR000516 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: NA

Molecular weight: Translated: 27804; Mature: 27673

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00883 NI_HGENASE_CYTB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYKEAFMQNKEEKLQRKAEYEFSIGLRLTHWVRAVAIVILIGTGYYLSYVFQSPISNG
CCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPVNFMQAKYRLVHQAVGFVLIACIVFKVYLFFCDKISAKERRSVWDIFNIKLWIEQVKF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YIFLGKHPHLKGVYNPLQFVTYFFFYLVILGIILTGLILYTHTYHEGLGGFLYHILRPLE
HHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMGGLADVRTYHRILMWVIMIFVPVHIYMAIFNAVKGKDGAMDAIISGYKYVKEEKH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIYKEAFMQNKEEKLQRKAEYEFSIGLRLTHWVRAVAIVILIGTGYYLSYVFQSPISNG
CHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPVNFMQAKYRLVHQAVGFVLIACIVFKVYLFFCDKISAKERRSVWDIFNIKLWIEQVKF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YIFLGKHPHLKGVYNPLQFVTYFFFYLVILGIILTGLILYTHTYHEGLGGFLYHILRPLE
HHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMGGLADVRTYHRILMWVIMIFVPVHIYMAIFNAVKGKDGAMDAIISGYKYVKEEKH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced ferredoxin; 2 H+ [C]

Specific reaction: Reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2 [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1587288; 8319698; 14500908 [H]