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The map label for this gene is pyrH [H]

Identifier: 153952363

GI number: 153952363

Start: 396526

End: 397245

Strand: Direct

Name: pyrH [H]

Synonym: JJD26997_0451

Alternate gene names: 153952363

Gene position: 396526-397245 (Clockwise)

Preceding gene: 153951727

Following gene: 153951415

Centisome position: 21.49

GC content: 33.47

Gene sequence:

>720_bases
ATGCAAGAGAGAAAAAGAGTTTTAGTAAAATTTTCAGGAGAGGCTTTAGCGGGTGAAAATGGCTTTGGTATAGAAAATTC
TATTTTAAAATTCATAGCTTCAGAGATTAAAGAACTTATAAAAAATCAAATAGAAGTAGGTATAGTTATAGGTGGTGGTA
ATATTATTCGCGGAGTAAGTGCTGCTAAGGGCGGATTGATTAAAAGGACAAGTGGAGATCATATGGGAATGCTTGCTACG
GTTATCAATGCTATTGCTATACAAGAAGCTTTGGAAAGGTCTGGACTTGAAGTTAGGGTTCAAAGCGCCATTCAGATGGA
AGCATTTTGTGAAACTTATATTATGAGAAGAGCGCAAAGACACTTAGAAAAGGGTCGTGTTGTGGTTTTTGCTGCAGGTA
CTGGAAACCCTTATTTTACTACAGATACAACAGCAATTTTAAGGGCTGTAGAAATTGATGCAGATATGGTAATAAAAGCT
ACAAAAGTTAATGGAGTTTATGATAAAGATCCAAAACAATTTGATGATGCAGTATTTTTAAATACTTTAAGTTATGATGA
GGCTATGCAAGATAATATTAAAGTGATGGATGATACAGCTATAGCTTTAGCTAAAGATAACAAACTTCCTATTGTGGTTT
GTAATATGTTTGAAGAGGGTAATTTGCTTAAAATCATACAAGGTGATACTAGCCTTTGTTCAATCGTTAAAAATAATTAA

Upstream 100 bases:

>100_bases
TCAAAAAAATTTTCATATCAATCCTTTGGAACTCATTAGTTTAAATTAGCTAAATTTAATGGAATTTAAAATATAATTTC
AAGTTAAATAAGGAGAAATA

Downstream 100 bases:

>100_bases
GGAGAAAATTATGGATAAAAGAATAGAAGAAGTAGCGGCAAAAGCTTTAGAAAAAATGGGTAATGATAGATATCGCCTTT
CTTTAGTGGTAGCAAAAAGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVSAAKGGLIKRTSGDHMGMLAT
VINAIAIQEALERSGLEVRVQSAIQMEAFCETYIMRRAQRHLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKA
TKVNGVYDKDPKQFDDAVFLNTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN

Sequences:

>Translated_239_residues
MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVSAAKGGLIKRTSGDHMGMLAT
VINAIAIQEALERSGLEVRVQSAIQMEAFCETYIMRRAQRHLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKA
TKVNGVYDKDPKQFDDAVFLNTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN
>Mature_239_residues
MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVSAAKGGLIKRTSGDHMGMLAT
VINAIAIQEALERSGLEVRVQSAIQMEAFCETYIMRRAQRHLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKA
TKVNGVYDKDPKQFDDAVFLNTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=225, Percent_Identity=50.2222222222222, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26101; Mature: 26101

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVS
CCCHHEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHEECCH
AAKGGLIKRTSGDHMGMLATVINAIAIQEALERSGLEVRVQSAIQMEAFCETYIMRRAQR
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
HLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKATKVNGVYDKDPKQFDDAVFL
HHHCCCEEEEEECCCCCEEECCHHHHHHHEECCCCEEEEEEEECCCCCCCCHHHCCEEEE
NTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN
EECCHHHHHHCCCEEECCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCHHHHEEECC
>Mature Secondary Structure
MQERKRVLVKFSGEALAGENGFGIENSILKFIASEIKELIKNQIEVGIVIGGGNIIRGVS
CCCHHEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHEECCH
AAKGGLIKRTSGDHMGMLATVINAIAIQEALERSGLEVRVQSAIQMEAFCETYIMRRAQR
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
HLEKGRVVVFAAGTGNPYFTTDTTAILRAVEIDADMVIKATKVNGVYDKDPKQFDDAVFL
HHHCCCEEEEEECCCCCEEECCHHHHHHHEECCCCEEEEEEEECCCCCCCCHHHCCEEEE
NTLSYDEAMQDNIKVMDDTAIALAKDNKLPIVVCNMFEEGNLLKIIQGDTSLCSIVKNN
EECCHHHHHHCCCEEECCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA