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The map label for this gene is mtnA [H]

Identifier: 153952345

GI number: 153952345

Start: 123593

End: 124279

Strand: Direct

Name: mtnA [H]

Synonym: JJD26997_0124

Alternate gene names: 153952345

Gene position: 123593-124279 (Clockwise)

Preceding gene: 153952364

Following gene: 153951034

Centisome position: 6.7

GC content: 34.21

Gene sequence:

>687_bases
ATGAAAATAGCAATTTTAGGAGCCATGAGTGAAGAAATCACTCCTTTACTTGAAACACTTAAAGATTATACGAAAATAGA
ACACGCTAACAATACTTATTATTTTGTAAAGTATAAAAACCATGAACTTGTTTTAGCGTATTCTAAAATCGGCAAGGTAA
ATTCTACTCTTAGTGCTAGTGTGATGATAGAAAAATTTGGCGCACAAGCGTTGCTTTTTACGGGCGTTGCAGGTGCTTTT
AATCCTGAATTTGAAATTGGCGATTTGCTTTATGCAACAAAATTAGCCCAATACGATCTTGATATTACTGCTTTTGGGCA
TCCTTTGGGTTTTGTTCCAGGTAATGAAATTTTTATCAAAACCGATGAGAAATTAAACAATCTTGCTTTAGAAGTTGCTA
AGGAATTAAATATCAAACTTCGTGCAGGTATTATTGCAACGGGTGATGAGTTTATTTGCGATGAAGCAAAAAAAGCAAAA
ATTAGAGAAATTTTCAATGCGGATGCTTGTGAAATGGAAGGCGCAAGTGTGGCTTTGGTTTGTGATGCTTTAAAGGTGCC
TTGTTTTATTTTAAGAGCTATGAGTGATAAAGCAGGGGAAAAGGCTGAATTTGATTTTGATGAGTTTGTGATCAATTCAG
CTAAAATTTCAGCCAATTTTGTGCTTAAAATGTGCGAGAAATTATGA

Upstream 100 bases:

>100_bases
GCGCAAGTGTGCTTAAGGGTTTAAATAAAAAAATCACTTCAAAAGAAACTTATGCTTTAACAAATATGAATGATATTGAT
GAATTTTTAAAGGTTATATG

Downstream 100 bases:

>100_bases
TAAATCTTAGTAAAAAACTCATACGCCAAGTTGCACAAGCTAATGCTAAATTTGGACTTATTAAGGATGGAGATAGGGTT
CTTTTAGGGCTTAGTGGTGG

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFVKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGAF
NPEFEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAK
IREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL

Sequences:

>Translated_228_residues
MKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFVKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGAF
NPEFEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAK
IREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
>Mature_228_residues
MKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFVKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGAF
NPEFEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAK
IREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=229, Percent_Identity=36.2445414847162, Blast_Score=126, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25156; Mature: 25156

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFVKYKNHELVLAYSKIGKVNSTLSAS
CEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHH
VMIEKFGAQALLFTGVAGAFNPEFEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIK
HHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
TDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAKIREIFNADACEMEGASVALV
CCCHHHHHHHHHHHHCCEEEEEEEEECCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEE
CDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
EHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFVKYKNHELVLAYSKIGKVNSTLSAS
CEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHH
VMIEKFGAQALLFTGVAGAFNPEFEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIK
HHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
TDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAKIREIFNADACEMEGASVALV
CCCHHHHHHHHHHHHCCEEEEEEEEECCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEE
CDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
EHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]