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The map label for this gene is kdsA [H]

Identifier: 153952090

GI number: 153952090

Start: 1392743

End: 1393546

Strand: Direct

Name: kdsA [H]

Synonym: JJD26997_1574

Alternate gene names: 153952090

Gene position: 1392743-1393546 (Clockwise)

Preceding gene: 153951705

Following gene: 153951681

Centisome position: 75.48

GC content: 35.2

Gene sequence:

>804_bases
ATGAAAAAAATGATACTCATTGCTGGTCCTTGTGTGATAGAAAGCAAAGATTTGATTTTTAAAGTTGCCAAACAATTAAA
AAATTTTAATGAGAATCCAAATATAGAATTTTATTTCAAATCAAGTTTTGATAAGGCCAATCGCACAAGTATTAATTCTT
TTCGAGGTCCTGGTCTTGAAGAAGGATTAAAAATTTTACAAAGCGTAAAAGATGAATTTGGTATGAAAATCTTAACCGAT
ATACACGAAAGCAATCAAGCAAACCCTGTAAGTGAAGTAGCTGATGTCTTGCAAATTCCTGCTTTTTTATGTCGTCAAAC
CGATTTACTTGTGGCCGCAGCAAAAACTAAGGCAAAAGTTAATATCAAAAAAGGGCAATTTTTAAACCCAAGCGATATCA
AATACAGCGTTAAAAAAGTTCTACAAACCCGTGGCATAGAAGATGAAGGCTATGAAGCAGCTCAAAAAAATGGTGTTTTT
GTAGCTGAAAGAGGAGCTAGCTTTGGCTATGGAAATTTAGTAGTAGATATGCGTTCTTTAGTTATCATGCGTGAATTTGC
TCCAGTAATTTTTGATGCTACTCATAGTGTACAAATGCCAGGGGCTGCAGGTGGAAGTAGCGGAGGGAAAAGTGAATTTG
TAGAACCTTTAGCAAGAGCAGCGGCAGCCGTAGGCATAGATGGCTTTTTCTTTGAAACACATATTAATCCTTGCGAGGCT
TTATGTGATGGACCTAATATGCTTGATCTTACACGCCTTAAAAATTGCGTTAATACATTACTAGAAATACAAAATATCAT
ATAA

Upstream 100 bases:

>100_bases
GGATAATTTTAGGAGATAATTTACCAAGTACTATGGTTTTTTTAGGTATAATAAGCATTATTTTTGGTGGATTAATTTTA
GTTAAGAACAAAGGAAAAAA

Downstream 100 bases:

>100_bases
GGAAAATAAATGAATATTATTGAAGGAAAATTAAATTTAGATTCAAATACAAAAATTGCTATCATCAATGCAAGATTTAA
TCATATCATCACAGATCGCC

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKKMILIAGPCVIESKDLIFKVAKQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLEEGLKILQSVKDEFGMKILTD
IHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKVNIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQKNGVF
VAERGASFGYGNLVVDMRSLVIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEA
LCDGPNMLDLTRLKNCVNTLLEIQNII

Sequences:

>Translated_267_residues
MKKMILIAGPCVIESKDLIFKVAKQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLEEGLKILQSVKDEFGMKILTD
IHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKVNIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQKNGVF
VAERGASFGYGNLVVDMRSLVIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEA
LCDGPNMLDLTRLKNCVNTLLEIQNII
>Mature_267_residues
MKKMILIAGPCVIESKDLIFKVAKQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLEEGLKILQSVKDEFGMKILTD
IHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKVNIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQKNGVF
VAERGASFGYGNLVVDMRSLVIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEA
LCDGPNMLDLTRLKNCVNTLLEIQNII

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=266, Percent_Identity=44.7368421052632, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29239; Mature: 29239

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMILIAGPCVIESKDLIFKVAKQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLE
CCCEEEEECCEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCHH
EGLKILQSVKDEFGMKILTDIHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKV
HHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEE
NIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQKNGVFVAERGASFGYGNLVVDMRSL
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHH
VIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEA
HHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LCDGPNMLDLTRLKNCVNTLLEIQNII
HCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKMILIAGPCVIESKDLIFKVAKQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLE
CCCEEEEECCEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCHH
EGLKILQSVKDEFGMKILTDIHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKV
HHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEE
NIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQKNGVFVAERGASFGYGNLVVDMRSL
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHH
VIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEA
HHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LCDGPNMLDLTRLKNCVNTLLEIQNII
HCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA