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The map label for this gene is dtpT [H]

Identifier: 153951626

GI number: 153951626

Start: 1187234

End: 1188784

Strand: Direct

Name: dtpT [H]

Synonym: JJD26997_1345

Alternate gene names: 153951626

Gene position: 1187234-1188784 (Clockwise)

Preceding gene: 153951072

Following gene: 153952590

Centisome position: 64.35

GC content: 30.69

Gene sequence:

>1551_bases
ATGAAGGGGACTCAGAATTTAGATACTTCATTTTTTGGACATCCAAAACCACTTTTATCTCTTTCACTTGCTGAGCTTTG
GGAAAGATTTTCTTTTTACGGAATTCGTCCCTTGCTTTACCTTTTTATGATAGCAAGTTTTGAAAAAAGTGGAATGAACT
TAAAACCTGAAGAAGCAAGTGCAATTATGGGAATTTTTGCAAGTTGTTTATATCTTGCTGCTTTGCCAGGTGGATGGCTT
GCGGATAATTACTTAGGACAAAAAAGAGCAATTTTACTAGGTGCTTTAACCATAGCATTTGGACATTTATGCATAGCCTT
TTCTTATTTTAACAATAAAATGATTTTTGTTGGTATGGTTTTTTTGGTTATAGGCACAGGACTTTTTAAAACTTGTGCTT
CTGTAATGGTTGGCATGCTTTATAAAAAAGATGATGCAAGGCGTGATTCTGGTTTTACTCTTTTTTATATGTGTTTTAAT
TTTGGTGCTTTTGCAGCTCCTTTAATTTGTGGCTTTTTACAAAAAGAATACGGATGGCATTTTGGTTTTGGTGCGGGTGG
GATTGGTATGCTTTTAGCGGTAATTATTTTCTACCTAAAAACTATGCCTGATTTAAAGGAATTTGATGAAAAAGTTGGCA
TAGACTCTACTTGGGATAGACCAAGCAAAAAAAGCAAAAACGCATTTTACATCATCATTGTATCAGGTATTGTTTTACTT
GGAGCAATATTTTTAATCCTTGGTGGTTTTATAAAATTAGATGCACAAGTTATTAATAAAAATATTATTTTAACTATCTT
AGCTTGTGCTGGAATTTATTTTTTATATCTTTTCGCTTTTACTTCTTTAAAAATAGAAGAAAAAAGAAATTTAATTATTT
TTATTGTTTTATTTTTAGCGGCTGCGTTATTTTGGTCAGTATATGAGCAACAATACACTTCTTTTAATTTTTTTGCAGAA
AAATTAACAGATAAAACCATATTAAATTATGAAATTCCTACAATATGGTTTCAATCTCTTGGAGGTTTATTTGTTATACT
TTTTGCACCTTTTAGTGCTTTTATATGGACTATATGCGCCAAAAACAATAAAGAAATTTCATCTATTATTAAATTTGCAT
TAGGACTTTTGGGTGCAGCTTTAGCATTTTTAATAATGGCTTTAGCTTCAAATCATGCAATTAGTTTAAATGGCGATGCT
AATACATTAAGAGAAAATTTAGAAAATTCATCACAAATTATTTTAGTTTCACCTTGGTGGCTTGTCAGTAGCTTTTTGCT
TATGGTTTTAGGAGAGCTTTGCCTTTCCCCTGTGGGACTTTCTATAATGACAAAAATTGCACCTAATTTAATTAAATCTC
AAGTCATGGGACTTTGGTTTGTAGCAAGTGCATTAGGCAATGCTTTAGCTGGATTCATAGGTGGTAAAGCAAGTGAAGAA
AATATAGCTTATTTGCCAAATTTATTTTACCAATGTATGTGGATATTACTTGGTGCTGTTATAATTTTACTTATACTCAA
AAAACCTATCAATAAAATACTAAAAAATTAA

Upstream 100 bases:

>100_bases
CTGATTTATTTGGGCAATGTATGTGGGTTTTGTTCATCATGAGTGCAGTTTTATTTTTAATTAAAAAACCTGTTTATAAT
ATGTTGAATAAGGAGTGAAA

Downstream 100 bases:

>100_bases
TATTAAGGAAAAAATATGAGTATTTACAAACAAAGAGTATTAGAACTTAGAAGATTAATGAAAGAAAATAATATTGACGC
CTATCTCATCTTAAGCGCGG

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKGTQNLDTSFFGHPKPLLSLSLAELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGWL
ADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKDDARRDSGFTLFYMCFN
FGAFAAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVLL
GAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFAE
KLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGDA
NTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASEE
NIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN

Sequences:

>Translated_516_residues
MKGTQNLDTSFFGHPKPLLSLSLAELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGWL
ADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKDDARRDSGFTLFYMCFN
FGAFAAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVLL
GAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFAE
KLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGDA
NTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASEE
NIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN
>Mature_516_residues
MKGTQNLDTSFFGHPKPLLSLSLAELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGWL
ADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKDDARRDSGFTLFYMCFN
FGAFAAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVLL
GAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFAE
KLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGDA
NTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASEE
NIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=406, Percent_Identity=22.4137931034483, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI21717816, Length=493, Percent_Identity=23.1237322515213, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI226371746, Length=375, Percent_Identity=22.1333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789911, Length=513, Percent_Identity=28.2651072124756, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1787922, Length=482, Percent_Identity=28.6307053941909, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1790572, Length=479, Percent_Identity=27.1398747390397, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1786927, Length=479, Percent_Identity=26.7223382045929, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71987453, Length=382, Percent_Identity=23.8219895287958, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 57257; Mature: 57257

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTQNLDTSFFGHPKPLLSLSLAELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHH
AIMGIFASCLYLAALPGGWLADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMV
HHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLVIGTGLFKTCASVMVGMLYKKDDARRDSGFTLFYMCFNFGAFAAPLICGFLQKEYGWH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
FGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVLL
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHH
GAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCHHHHHHHHHH
AALFWSVYEQQYTSFNFFAEKLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGDANTLRENLENSSQIILVSPWW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCEEEECCHH
LVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASEE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]