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The map label for this gene is purL [H]

Identifier: 153951583

GI number: 153951583

Start: 744289

End: 746475

Strand: Direct

Name: purL [H]

Synonym: JJD26997_0826

Alternate gene names: 153951583

Gene position: 744289-746475 (Clockwise)

Preceding gene: 153952344

Following gene: 153951540

Centisome position: 40.34

GC content: 35.12

Gene sequence:

>2187_bases
ATGGATAAAGAAACCATAAAAGCACATAAAATCAGCGATGAAGAATATACACAAATTTTAGAAATTTTAGGACGTGAGCC
AAATTTATTAGAACTTGGGGTTATTTCTGCGATGTGGAGTGAGCATTGCTCTTATAAATCCAGTAAAAAATATCTTAATG
GTTTTCCAACTAAAGCACCTTGGGTGATTCAAGGTCCAGGAGAAAACGCAGGAGTTATTGATATTGGGCAAGGTATGTCA
GCAGTTTTTAAAGTAGAAAGTCACAATCATCCTAGCTTTATCGAACCTTTTGCAGGTGCAGCTACGGGAGTAGGGGGAAT
TTTGCGTGATGTTTTTACTATGGGTGCAAGAGTGGTTGCGGGGTTAAATTCTTTAAAATTTGGCGATATTCATAATGAAA
AATGCGGCAAACATCAAAAATACCTTGTTAAAGGCGTGGTAAATGGAATTTCTCATTATGGAAATTGCATGGGTGTGCCA
ACTATAGGTGGAGAATGTGCTTTTGATGAGTGTTTTAATGGAAATATCTTAGTTAATGCCTTTGCTTTAGGGATTTGTAA
AAGTGAAGATATCTTTTATGCTAAGGCTGAAGGTGTAGGAAATCCTGTGATTTATGTGGGTTCAAAAACAGGGCGTGATG
GACTTGGTGGAGCGGTTATGGCAAGTGATAGCTTCAATGAAGAAAGTAAATCCTTACGCCCAACTGTACAAATTGGCGAT
CCTTTCAGTGAAAAACTTCTTATGGAGGCTTGTTTAGAGCTTTTTAAAACTGATTATATCGTAGGTATTCAAGATATGGG
TGCTGCAGGGCTTACTTCAAGTTCTTTTGAAATGGCAGGAAGAAGTGGCAGTGGTATGAAGCTTTACTTAGATAAAACTC
CTATGCGTGAAAGCGGTATGACTCCTTATGAGTTAATGCTTAGCGAATCTCAAGAAAGAATGCTTATTTGTGCGAAAAAA
GGCTATGAAGATAAGGTTATAGAAATTTTTAAAAAATGGGATTTAGATGCTGTGGTTATAGGTGAAGTTACCAATACAGA
GAAAATGGAGCTTTTTTGGCATGATGAGCTTGTAGGACTTATTCCTATTGAGCCTTTAAGCGAAAAAGCACCGATTTTAA
ATCGTCCTATAAGTGAGCCAAAATATTTAAGTGAAATTAAAGACTATAAATTTGAGTTAAAATCAAGCATTCAAGAGCTT
TTTATACAAATGCTTCAAAATGAAAATATTAACAACAAAGCTTTTATTTATGATCAATTTGATTCAAGCGTGCAAACCAA
TACCATAAAAGCTGATGGAAAATTAGGTGCTAGTGTTATTCGTATCAAAGAAAATGGTGTAAGTGTGGCTATGGCTATAG
AATGTAACTCACGCTTAAATTATGTAAATCCTAAAATAGGAGCAGCTTTAGCAGTAGCTTCTGCAGGAAGAAAAGTTGCT
TGCACAGGAGCTAAGCCTTTGGCAATAAGCGATTGTTTAAATTATGGAAATCCGCAAAATCCTGAAGTGATGTGGCAATT
CGCACAAGGTTGTGAAGGTATTAAAGAAGCTTGTAAAGAGTTAAATACCCCAGTAGTAAGCGGCAATGTTTCACTTTATA
ATGAAACTGAAGGTGTAAGTATTTATCCAAGTCCTACTATAGTAAGCGTAGGGGTTTTAGAAGATGCAAACAAAACCTTA
AAAGCTAGTTTTGAAAAAGAAAATTTAAGCGTTTATCTTTTGGGTGAAAGTTTAGGAGAATTTGGTGGATCTATGGTAAT
GAAAATCCAAGATAAAAAAGTATCAGGAAGCCTTAAAGAGCTTGATTATAAAGCTGAACTTGCACTTTGGGATCTGCTTT
ATAAAGCCAATCAAAATTCTTTACTTGAGTGTGCCAATAGCGTAGGAATAGGTGGAATTGCTATGACTTTGGCAAAAATG
TTTGCTATTTCTAGTGTGGGTGCAAATTTAACAAGTGGTTTTGATGATGAAAAAATGATTTTTGATGAGAGTGCAAGTCG
TGCTATAGTAGGGCTTAGTAAAGAAAATGAAGAAACTTTTTTAACTTTAACTAAAGAATTTGGAGTAAAAGCTTATAAAT
TAGGCGTGAGTACTAGCCAAAAACATTTTAAACTTGATAGTATTGAGCTAAATAAAGCTGAACTTGATAAGCTTTATTTT
GAAAGTTTTCAAGAGCAAATCCAATGA

Upstream 100 bases:

>100_bases
GCTATTAATGAACTTGCAAGATTTACCAAAGATTTTCAAAGAGATGAAATTTTAGACGAAATGTTTGGTAATTTTTGTTT
AGGAAAATGAAAGGATAAAA

Downstream 100 bases:

>100_bases
CTCTAGTTTTAATTATACTTGTTGTTTTGGTGTTTTACTGGTATTATAAAACTTGGGGAAAGCAGGATTTTTTAAACTCA
GCCACAAGAGGAGCCAAAGG

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMS
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGDIHNEKCGKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGICKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTEKMELFWHDELVGLIPIEPLSEKAPILNRPISEPKYLSEIKDYKFELKSSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGKLGASVIRIKENGVSVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEETFLTLTKEFGVKAYKLGVSTSQKHFKLDSIELNKAELDKLYF
ESFQEQIQ

Sequences:

>Translated_728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMS
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGDIHNEKCGKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGICKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTEKMELFWHDELVGLIPIEPLSEKAPILNRPISEPKYLSEIKDYKFELKSSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGKLGASVIRIKENGVSVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEETFLTLTKEFGVKAYKLGVSTSQKHFKLDSIELNKAELDKLYF
ESFQEQIQ
>Mature_728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMS
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGDIHNEKCGKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGICKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTEKMELFWHDELVGLIPIEPLSEKAPILNRPISEPKYLSEIKDYKFELKSSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGKLGASVIRIKENGVSVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEETFLTLTKEFGVKAYKLGVSTSQKHFKLDSIELNKAELDKLYF
ESFQEQIQ

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=466, Percent_Identity=24.6781115879828, Blast_Score=81, Evalue=4e-15,
Organism=Escherichia coli, GI48994899, Length=787, Percent_Identity=23.8881829733164, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321498, Length=502, Percent_Identity=25.2988047808765, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 79460; Mature: 79460

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
WVIQGPGENAGVIDIGQGMSAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVA
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GLNSLKFGDIHNEKCGKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNA
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCCCEEEEE
FALGICKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
EEEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHCCCCEEEECC
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGM
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCC
TPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVIGEVTNTEKMELFWHDELVGL
CHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCEEEE
IPIEPLSEKAPILNRPISEPKYLSEIKDYKFELKSSIQELFIQMLQNENINNKAFIYDQF
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DSSVQTNTIKADGKLGASVIRIKENGVSVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CCCCCCCEEEECCCCCCEEEEEEECCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEE
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVS
ECCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEE
IYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKE
ECCCCCEEEEEEECCCCCHHHCCCCCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCHHH
LDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSGFDDEKMI
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEE
FDESASRAIVGLSKENEETFLTLTKEFGVKAYKLGVSTSQKHFKLDSIELNKAELDKLYF
ECCCCCCEEEEECCCCCCEEEEEEHHHCCEEEEECCCCCCCCEEECCEECCHHHHHHHHH
ESFQEQIQ
HHHHHHCC
>Mature Secondary Structure
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
WVIQGPGENAGVIDIGQGMSAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVA
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GLNSLKFGDIHNEKCGKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNA
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCCCEEEEE
FALGICKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
EEEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHCCCCEEEECC
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPMRESGM
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCC
TPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVIGEVTNTEKMELFWHDELVGL
CHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCEEEE
IPIEPLSEKAPILNRPISEPKYLSEIKDYKFELKSSIQELFIQMLQNENINNKAFIYDQF
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DSSVQTNTIKADGKLGASVIRIKENGVSVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CCCCCCCEEEECCCCCCEEEEEEECCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEE
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVS
ECCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEE
IYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKE
ECCCCCEEEEEEECCCCCHHHCCCCCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCHHH
LDYKAELALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSGFDDEKMI
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEE
FDESASRAIVGLSKENEETFLTLTKEFGVKAYKLGVSTSQKHFKLDSIELNKAELDKLYF
ECCCCCCEEEEECCCCCCEEEEEEHHHCCEEEEECCCCCCCCEEECCEECCHHHHHHHHH
ESFQEQIQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA