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The map label for this gene is ribE [H]

Identifier: 153951102

GI number: 153951102

Start: 457742

End: 458353

Strand: Direct

Name: ribE [H]

Synonym: JJD26997_0512

Alternate gene names: 153951102

Gene position: 457742-458353 (Clockwise)

Preceding gene: 153952028

Following gene: 153952013

Centisome position: 24.81

GC content: 31.7

Gene sequence:

>612_bases
ATGTTTAATGGACTCATAAGAGAAATTGCTAAAGTTCAATCTTATCAAAACAATACTTTAAGTTTAAAAGCCAAGTATCG
TCCAAATCTTGGAGATAGCATAGCCGTAAATGGAGCTTGTTTAAGTGTAACAAAACTTTATGAAGGGGGTTTTGAAGTGG
AGCTTTCTCGTGAAAGTCGCACTCATATAGCTATAGAAAATTTAAAAGATAAGGTTCATATAGAACCTGCTTTAAGATAT
GGTGATAGAATCGATGGGCATCTCATGCAAGGGCATATTGATTTTATCGGCACGCTTGAAAAGATTCAAAAAGATGAAAA
TGGAGTGGATTTTCATATATCTTTGCCTAAAGAAGCTATGAAATTTATGGCAGAAAAAGGAAGTATAGCTGTTGATGGGG
TAAGCCTTACTATCAATGAAATTTTAAAAAATGGCATTAGGCTTACTATTATTCCTATTACTTTTAAAGAAACGCTTTTT
AAAGACTATCAAGTAGGTAGAAAAATAAATATAGAAAGTGATTTACTTGTTCGTTATATTTATGCACAATTGCAAGGTAA
AAACAAAGGATTATCATGGGAAGAAGTGGAAAGAATTTCTTATCTTTATTAG

Upstream 100 bases:

>100_bases
ACGTAGTGGGTGGTGGCGTGAGTAATGGTGCTAAAAATACAGGAGATAAAGTGGATAAAGCGGTGAATAAATTATTAAAT
AAGATTTTTTAAGGTAAAAA

Downstream 100 bases:

>100_bases
AAAATGATAAAGTCGGTATTTTTTGTGCTTTTGATAAGGATTATAATGTTTTTAGAGCTAAGGTTTATAATGAGAATTTA
TTTTCTCATTTAGGTTTTAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFNGLIREIAKVQSYQNNTLSLKAKYRPNLGDSIAVNGACLSVTKLYEGGFEVELSRESRTHIAIENLKDKVHIEPALRY
GDRIDGHLMQGHIDFIGTLEKIQKDENGVDFHISLPKEAMKFMAEKGSIAVDGVSLTINEILKNGIRLTIIPITFKETLF
KDYQVGRKINIESDLLVRYIYAQLQGKNKGLSWEEVERISYLY

Sequences:

>Translated_203_residues
MFNGLIREIAKVQSYQNNTLSLKAKYRPNLGDSIAVNGACLSVTKLYEGGFEVELSRESRTHIAIENLKDKVHIEPALRY
GDRIDGHLMQGHIDFIGTLEKIQKDENGVDFHISLPKEAMKFMAEKGSIAVDGVSLTINEILKNGIRLTIIPITFKETLF
KDYQVGRKINIESDLLVRYIYAQLQGKNKGLSWEEVERISYLY
>Mature_203_residues
MFNGLIREIAKVQSYQNNTLSLKAKYRPNLGDSIAVNGACLSVTKLYEGGFEVELSRESRTHIAIENLKDKVHIEPALRY
GDRIDGHLMQGHIDFIGTLEKIQKDENGVDFHISLPKEAMKFMAEKGSIAVDGVSLTINEILKNGIRLTIIPITFKETLF
KDYQVGRKINIESDLLVRYIYAQLQGKNKGLSWEEVERISYLY

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=31.3513513513514, Blast_Score=87, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=162, Percent_Identity=33.9506172839506, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23078; Mature: 23078

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNGLIREIAKVQSYQNNTLSLKAKYRPNLGDSIAVNGACLSVTKLYEGGFEVELSRESR
CCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCHHEEEEHHHCCCEEEEECCCCC
THIAIENLKDKVHIEPALRYGDRIDGHLMQGHIDFIGTLEKIQKDENGVDFHISLPKEAM
CEEEEECCCCEEEECHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEECCHHHH
KFMAEKGSIAVDGVSLTINEILKNGIRLTIIPITFKETLFKDYQVGRKINIESDLLVRYI
HHHHCCCCEEEECCEEEHHHHHHCCCEEEEEEEEHHHHHHHHHHCCCEECCCHHHHHHHH
YAQLQGKNKGLSWEEVERISYLY
HHHHCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFNGLIREIAKVQSYQNNTLSLKAKYRPNLGDSIAVNGACLSVTKLYEGGFEVELSRESR
CCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCHHEEEEHHHCCCEEEEECCCCC
THIAIENLKDKVHIEPALRYGDRIDGHLMQGHIDFIGTLEKIQKDENGVDFHISLPKEAM
CEEEEECCCCEEEECHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEECCHHHH
KFMAEKGSIAVDGVSLTINEILKNGIRLTIIPITFKETLFKDYQVGRKINIESDLLVRYI
HHHHCCCCEEEECCEEEHHHHHHCCCEEEEEEEEHHHHHHHHHHCCCEECCCHHHHHHHH
YAQLQGKNKGLSWEEVERISYLY
HHHHCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]