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The map label for this gene is uvrC [H]

Identifier: 153951039

GI number: 153951039

Start: 428461

End: 430263

Strand: Direct

Name: uvrC [H]

Synonym: JJD26997_0480

Alternate gene names: 153951039

Gene position: 428461-430263 (Clockwise)

Preceding gene: 153952552

Following gene: 153952310

Centisome position: 23.22

GC content: 29.17

Gene sequence:

>1803_bases
TTGACTAAAGAGAAATTAGAAAATGAGTTAAAAACTCTTCCTAATAGCGCTGGAGTATATGAATACTTTAATCAAGAAGG
GAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAGGAAATTCTTTAAGAATTCAAAAAATGATTCAAGAAACAGTGCATTTGGAATTTATCACTACTAATTCAGAA
GCCGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTACTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTAAAGAAGAATTTCCACGCTTTGAAATCACTAGAAAATTGGTAAAAAAAAGCAAAA
TCAAATATTTTGGCCCTTTTTTTAAGGGTGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGCTGTCTTGCACCTTGTGATAAACGCATTAGCAAGGAAAA
ATATCGTGAAATTTTAGATGAGGCTATGCATGCACTTTTAAATCCTAGCGTTTTACTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCGCAAAATGAAAATTACGAAGAAGCAGCAAAGATAAGGGATCAGATTGCAACGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTGTTTGCTTTAGCTTTTAAAAATTCTATGCTTTCAACCTT
GCGTTTTGTGGTACAAAATGGAAAAATTATCAGTGTAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAGCGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAATGCTTTTGGAAAAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAAAATTTGTGATTTGGCTTTTCAAAATGCACTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTACAAGGTGTGGCAAATGTTGGAGCTATGGTAACTTATAGCGTAAATTCTTGGGATAAGTCAAAATATCGTAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACACGCAGGGCTTTGGATTTTGATAAAATACCAC
CTCCTGATTTATGGCTTATAGATGGAGGAAAGGTTTTACTTGATTTGGCTAAAGAAATCATTTTAAGCACTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGGGCTAAAGGAGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGCTTAAGTGTTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TTAGGAGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTGGGTAAGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Upstream 100 bases:

>100_bases
TTGGAGCTTTCTAAGGGTGAATTTAAAAATTGCTTTGAAGATGAAAAATTATTTAAGAAATTTGAAGATTTAAGAGAACT
TATAAAAAAGGGTTCTAATC

Downstream 100 bases:

>100_bases
TTTGATATTAGCAGGGATAATTTTTATTTTTAATCTAATTTTAGCGTATTTAAGTATTGATATCTCAAAGCTTGATAGTG
TTACTGAACAACTGAAAATA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MTKEKLENELKTLPNSAGVYEYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPGNSLRIQKMIQETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFKEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISKEKYREILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKIRDQIATIKDLEV
KVEIDIAKLEDFEVFALAFKNSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLASVIYVY
EEFEDRMLLEKILSQRFDKKISIKIPKIGEKRKICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYSVNSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKEIILSTGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSVNDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
LGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN

Sequences:

>Translated_600_residues
MTKEKLENELKTLPNSAGVYEYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPGNSLRIQKMIQETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFKEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISKEKYREILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKIRDQIATIKDLEV
KVEIDIAKLEDFEVFALAFKNSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLASVIYVY
EEFEDRMLLEKILSQRFDKKISIKIPKIGEKRKICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYSVNSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKEIILSTGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSVNDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
LGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN
>Mature_599_residues
TKEKLENELKTLPNSAGVYEYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPGNSLRIQKMIQETVHLEFITTNSEA
DALILENSFIKQLHPKYNILLRDDKTYPYIYVDFKEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQKA
SCKSPCIFYQISRCLAPCDKRISKEKYREILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKIRDQIATIKDLEVK
VEIDIAKLEDFEVFALAFKNSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLASVIYVYE
EFEDRMLLEKILSQRFDKKISIKIPKIGEKRKICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNSH
LQGVANVGAMVTYSVNSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKEIILSTGANV
DILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSVNDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLSL
GVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=607, Percent_Identity=30.1482701812191, Blast_Score=240, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 69558; Mature: 69426

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEKLENELKTLPNSAGVYEYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPGNSL
CCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHEECCCCCCCCCCCH
RIQKMIQETVHLEFITTNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFKEEFP
HHHHHHHHHHEEEEEEECCCCCEEEECHHHHHHHCCCEEEEEECCCCCCEEEEECHHCCC
RFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQKASCKSPCIFYQISRCLAPCD
HHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KRISKEKYREILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKIRDQIATIKDLEV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCEEE
KVEIDIAKLEDFEVFALAFKNSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHH
LILENFSMDIPLLASVIYVYEEFEDRMLLEKILSQRFDKKISIKIPKIGEKRKICDLAFQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
NALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNSHLQGVANVGAMVTYSVNSWD
HHHHCCHHHCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCEEEEEEECCCC
KSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKEIILSTGAN
HHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSVNDKKLQFLQKLRDEAHRFAISFH
EEEEEECHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHEEEECC
QNTKKKQDLKSSKLANLGLSLGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKEKLENELKTLPNSAGVYEYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPGNSL
CHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHEECCCCCCCCCCCH
RIQKMIQETVHLEFITTNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFKEEFP
HHHHHHHHHHEEEEEEECCCCCEEEECHHHHHHHCCCEEEEEECCCCCCEEEEECHHCCC
RFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQKASCKSPCIFYQISRCLAPCD
HHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KRISKEKYREILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKIRDQIATIKDLEV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCEEE
KVEIDIAKLEDFEVFALAFKNSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHH
LILENFSMDIPLLASVIYVYEEFEDRMLLEKILSQRFDKKISIKIPKIGEKRKICDLAFQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
NALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNSHLQGVANVGAMVTYSVNSWD
HHHHCCHHHCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCEEEEEEECCCC
KSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKEIILSTGAN
HHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSVNDKKLQFLQKLRDEAHRFAISFH
EEEEEECHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHEEEECC
QNTKKKQDLKSSKLANLGLSLGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA