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The map label for this gene is ttcA [H]

Identifier: 153951034

GI number: 153951034

Start: 124276

End: 125037

Strand: Direct

Name: ttcA [H]

Synonym: JJD26997_0125

Alternate gene names: 153951034

Gene position: 124276-125037 (Clockwise)

Preceding gene: 153952345

Following gene: 153951597

Centisome position: 6.74

GC content: 35.83

Gene sequence:

>762_bases
ATGATAAATCTTAGTAAAAAACTCATACGCCAAGTTGCACAAGCTAATGCTAAATTTGGACTTATTAAGGATGGAGATAG
GGTTCTTTTAGGGCTTAGTGGTGGGAAAGATTCTTTAGCTTTAGCCCATCTTTTAAATCGTATGCAAGCCCATGTTCCTT
TTAAATTTGAACTTGAAGCGGTGACTTTGAGTTATGGCATGGGCGAGGATTATTCAGGGCTTCATGCACATTGTGAAGAA
CACGACATTAAACACAGTGTGCTTGATTCAAATATTTATGAAATGTCAGGCGATACCATAAGAGAAAATTCAAGTTTTTG
TAGTTATTTTTCGAGAATGCGTCGCGGGACTTTATATACTTACGCCCTTGAAAAAGGTTTTAACAAGCTTGCTATAGCTC
ATCATTTAGACGATGCAGCAGAAAGCTTTTTTATGAATTTTATTCATAATGGAGCTTTAAGAACCTTAGCGCCTATTTAT
CAAAGCAAACGCGGTGTAACTGTGATACGCCCTTTGATTTTTGTGCGAGAAAGGCAGCTTAGGAATAATGCTACGCAAAA
TGAACTTAGCGTGATAGGAAATGAATTTTGTCCTGGTATGAAATTAAGCGAAAAAAATGTAAAATTTCCACACGCTAGAG
AAGAAGCTAAACAGCTTTTAGCAAATTTAGAAAAAGATCATCCTAAGCTTTTTACAAGCTTAAAAACTGCTTTTGCAAAT
TTACACACAGAAAGTTTTTGGCTAGAAAGGACAAAAGTATGA

Upstream 100 bases:

>100_bases
GTGATAAAGCAGGGGAAAAGGCTGAATTTGATTTTGATGAGTTTGTGATCAATTCAGCTAAAATTTCAGCCAATTTTGTG
CTTAAAATGTGCGAGAAATT

Downstream 100 bases:

>100_bases
AAAAAGCTTTTGTTTTAGTGGATTATCAAAATGATTTTATTGATGGAAGTTTAGGTTTTGATAAGGCTTTAAAAATCAAA
GAAAATATTCTTAAAGCCTT

Product: PP-loop family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHVPFKFELEAVTLSYGMGEDYSGLHAHCEE
HDIKHSVLDSNIYEMSGDTIRENSSFCSYFSRMRRGTLYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGVTVIRPLIFVRERQLRNNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFAN
LHTESFWLERTKV

Sequences:

>Translated_253_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHVPFKFELEAVTLSYGMGEDYSGLHAHCEE
HDIKHSVLDSNIYEMSGDTIRENSSFCSYFSRMRRGTLYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGVTVIRPLIFVRERQLRNNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFAN
LHTESFWLERTKV
>Mature_253_residues
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHVPFKFELEAVTLSYGMGEDYSGLHAHCEE
HDIKHSVLDSNIYEMSGDTIRENSSFCSYFSRMRRGTLYTYALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIY
QSKRGVTVIRPLIFVRERQLRNNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFAN
LHTESFWLERTKV

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=240, Percent_Identity=31.6666666666667, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI193211090, Length=247, Percent_Identity=38.4615384615385, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17540090, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28728; Mature: 28728

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHVPFKFELEA
CCCHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEE
VTLSYGMGEDYSGLHAHCEEHDIKHSVLDSNIYEMSGDTIRENSSFCSYFSRMRRGTLYT
EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHCCCHHHHHHHHHHCCCEEE
YALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIYQSKRGVTVIRPLIFVRERQL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RNNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFAN
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LHTESFWLERTKV
HHHHHHHHHHCCC
>Mature Secondary Structure
MINLSKKLIRQVAQANAKFGLIKDGDRVLLGLSGGKDSLALAHLLNRMQAHVPFKFELEA
CCCHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEE
VTLSYGMGEDYSGLHAHCEEHDIKHSVLDSNIYEMSGDTIRENSSFCSYFSRMRRGTLYT
EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHCCCHHHHHHHHHHCCCEEE
YALEKGFNKLAIAHHLDDAAESFFMNFIHNGALRTLAPIYQSKRGVTVIRPLIFVRERQL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RNNATQNELSVIGNEFCPGMKLSEKNVKFPHAREEAKQLLANLEKDHPKLFTSLKTAFAN
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LHTESFWLERTKV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA