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The map label for this gene is asd [H]

Identifier: 153951010

GI number: 153951010

Start: 690730

End: 691761

Strand: Direct

Name: asd [H]

Synonym: JJD26997_0765

Alternate gene names: 153951010

Gene position: 690730-691761 (Clockwise)

Preceding gene: 153952060

Following gene: 153951483

Centisome position: 37.44

GC content: 31.88

Gene sequence:

>1032_bases
ATGTCAAAAAAACAAAAAATAGCCATTGTGGGTGCCACTGGTGCGGTTGGGGAAGAGCTTTTAAATGTTTTAGATGAACT
TGATTTTCCAGTGGAAAGTATTTTACCTTTAGCAAGTGCAAAAAGTGTAGGTAGTGAAGTAGAATTTAAAGGCAAAGCTT
ATAAAGTCAAAGAACTTACTGAAAATGTATTTAAAGAAAATCCTATTGATATTGCTTTTTTTAGTGCAGGTGGAAGTGTG
AGTGAAAAATATGCTAAATTTGCAGTAGAATCGGGTGCTGTTGTTATTGATAATACAAGTCATTTTAGAATGGAAAAAGA
TGTTCCTTTGGTGGTTCCTGAATGCAATCCTGAGGATATTAAAGATTGGAAAAAAACAGGGATTATTGCTAATCCAAATT
GTTCTACCATACAAATGGTGCAAGTTTTAAAACCTTTAAATGATGTATTTAATTTAAAGCGTGTTGATGTAAGCACCTAT
CAGGCTGCAAGTGGAGCAGGAAAAGAAGGAATGCAAGAATTGGTTAAAGCCATGCAAAGTTTTTTTGCTTTTAAACTTGA
TGAGTTTGAACCTCAAACTTTTCCTTATACTTTGGCGCTTAATCTTATTCCACAAATTGATGTTTTTATGGATAATGATT
ACACTAAAGAAGAACTTAAAATGGTTAATGAAACTCAAAAAATTTTACATAAAAATTTAGAAGTTTCAGCAACTTGTGTA
AGAGTGCCTGTTTTAAGAAGTCATAGTGAAGCTATTACTATGCATTTTGAAAAAGAAATAAATGTAAAAAAAGCTAAAGA
AATTTTAGAAAAAGCACCAAATGTTGTTGTCATAGATGATCCTAAAAATAAAAAATACCCTATGCCTTTAATGACTAGCG
ATACTAATGAAACTTATGTAGGAAGAATTCGTGCTGATGTGTATGATAAAAAAATACTCCATCTTTGGTGTGTGGCAGAT
CAAATTCGCGTAGGTGCTGCAACAAATGCTGTGCGTATTGCGCAAAAATGGTTAGAATTAAAAAATAAATAA

Upstream 100 bases:

>100_bases
TAAGTGTAGATTATGACAAGGATCAAGCTTCTCAAATTTTAGGTATGGATATAAAAATTTTAAATGAAAAAATTAAAAAA
TATCAAATAAAGGATAAGTA

Downstream 100 bases:

>100_bases
GGAAAAAAATGTTAGAGAAAATATTTGAATCTTTGCTTGTTAGAAGTCGTATTGTTACAATTTTACCCGTAATTTTTGGT
TTAATTGGAGCTTTTGTATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSV
SEKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDVFNLKRVDVSTY
QAASGAGKEGMQELVKAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
RVPVLRSHSEAITMHFEKEINVKKAKEILEKAPNVVVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVAD
QIRVGAATNAVRIAQKWLELKNK

Sequences:

>Translated_343_residues
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSV
SEKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDVFNLKRVDVSTY
QAASGAGKEGMQELVKAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
RVPVLRSHSEAITMHFEKEINVKKAKEILEKAPNVVVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVAD
QIRVGAATNAVRIAQKWLELKNK
>Mature_342_residues
SKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELTENVFKENPIDIAFFSAGGSVS
EKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNPEDIKDWKKTGIIANPNCSTIQMVQVLKPLNDVFNLKRVDVSTYQ
AASGAGKEGMQELVKAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCVR
VPVLRSHSEAITMHFEKEINVKKAKEILEKAPNVVVIDDPKNKKYPMPLMTSDTNETYVGRIRADVYDKKILHLWCVADQ
IRVGAATNAVRIAQKWLELKNK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=33.5276967930029, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789841, Length=371, Percent_Identity=29.1105121293801, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320362, Length=405, Percent_Identity=27.4074074074074, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38416; Mature: 38285

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELT
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCEEEHHHHH
ENVFKENPIDIAFFSAGGSVSEKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNPEDI
HHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEECCCCHHHH
KDWKKTGIIANPNCSTIQMVQVLKPLNDVFNLKRVDVSTYQAASGAGKEGMQELVKAMQS
HHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHH
FFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
HHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
RVPVLRSHSEAITMHFEKEINVKKAKEILEKAPNVVVIDDPKNKKYPMPLMTSDTNETYV
EEHHHHCCCCEEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCEE
GRIRADVYDKKILHLWCVADQIRVGAATNAVRIAQKWLELKNK
EEEEHHHHHHHHEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKQKIAIVGATGAVGEELLNVLDELDFPVESILPLASAKSVGSEVEFKGKAYKVKELT
CCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCEEEHHHHH
ENVFKENPIDIAFFSAGGSVSEKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNPEDI
HHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEECCCCHHHH
KDWKKTGIIANPNCSTIQMVQVLKPLNDVFNLKRVDVSTYQAASGAGKEGMQELVKAMQS
HHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHH
FFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKILHKNLEVSATCV
HHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
RVPVLRSHSEAITMHFEKEINVKKAKEILEKAPNVVVIDDPKNKKYPMPLMTSDTNETYV
EEHHHHCCCCEEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCCEE
GRIRADVYDKKILHLWCVADQIRVGAATNAVRIAQKWLELKNK
EEEEHHHHHHHHEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9127485; 10688204 [H]