BacMap

Definition	Clostridium botulinum A str. Hall, complete genome.
Accession	NC_009698
Length	3,760,560

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The map label for this gene is yvsH [H]

Identifier: 153937788

GI number: 153937788

Start: 452018

End: 453367

Strand: Direct

Name: yvsH [H]

Synonym: CLC_0453

Alternate gene names: 153937788

Gene position: 452018-453367 (Clockwise)

Preceding gene: 153936919

Following gene: 153934915

Centisome position: 12.02

GC content: 32.67

Gene sequence:

>1350_bases
ATGGAGGAGAATAATAAATTAAAAAAAGAAATAGGACTTTTTACTGCTACATTTATAGTGGCTGGTAATATAATTGGATC
AGGAATATTTATGCTTCCGGCTACCTTAGCGGAGGTATCAGGACCAGGAGCTACTATGGCAGCTTGGATTATAACTGGTA
TAGGTTCTATATTTTTAGCATTGTCCTTTGCACGATTAGGATCTAAAATTCCAAAAACGGGAGGTCCTTATCAATATGCT
AAAATAGCTTTTGGAGATTTTGTAGGCTTTACTAATGCATGGCTTTACTGGAGTGCTACATGCATATCCAACGCGGCTAT
AATAACGGCTATAGCAAGCTATTCTTCAAGTTTAGTTCCAGTTTTAAAAACTAATGGATTATACGCTTTTTTATATACCT
CTGCTATATTGTGGGCATTTAATATATTGAACATTATAGGGGTAAAACAAGCCAGTGCCTTTGAAACGGTTATAACTATA
TTTAAATTAGGAGTATTTTTAGTTTTTGTAATAATAGGTTTTGCCAATTTTAATCCACAATACATTACTCCTGCTTTTCC
AAAGGGTAAAGGGTTTAGTACAGTGCCCTTAGCAGCAGCAACTACATTATGGGCATTCTCTGGATTTGAATCCGCTAGTA
TAGCAGCAGGAGAGATAAAAAGTGCTGAAAAAAATGTTAAATTGAGTACTATTTATGGACTTCTAATAGCAGTGCTTGTA
TATTTAGTAATAAGCTTTGTTGCTATGGGCGGATTACCACAGGATATGTTAGCAAAAAGCAATTCTCCTATGAGTGATAT
ATTAGCTCTACATTTAAGTAGTAATGCTGTAAATCTATTTTTATTAGCTATTGTTATAACCATTTTTGGAACTATAGCAG
GATGGATAATGTTAACGGCTAGAATCTCTTATGCAGCAGCTGTAGATGGAATGTTTCCACAAGCTTTTGCTAAGATTCAT
CCTAAATATAGAACTCCTCATGTAGGGATTATAATAAATGGAATATTAACTAATATTGTTCTTTTGATGAACTATACAGG
TTCTATGACTTCTGCTTATAACTTTATGATTTTATTGGCTACGCTAGCATATTTACCTGTATATGCTATAACTAATGCTG
CAGATATATTACTTTTATCTAAAAGAGAAGAAAAATTTAATGTGGGAAATTTTATTATAAATTCTGTTGTTCCATTAATA
GGATTTATTTATGCTATTTGGGCAGTTTATGGAACAGGTGCCGAATCTGCCTTATATGGGTTATTATTAGGTTTAATGGG
CATACCATTTTATATCTATATGAAGATGAAAGACAAAAAACAGATGGAAAAGATAAGAAAACAACAATAA

Upstream 100 bases:

>100_bases
AAATAATAGTATTAATACAATTCAAATAATTATATGAAAATTTTTTATTATAGTATAGTTTATAGATTTTTACTAAAGAT
GAAATGAAAGGAGTATTAAT

Downstream 100 bases:

>100_bases
ATTTTGTAATATAATAATATTTTTAATAAAAAAGTGTCATATACTTTATTGTAATGATATAATAGACTTGTTGAAAGCCC
TGTGCAAATGTACAGGGTTT

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEENNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ

Sequences:

>Translated_449_residues
MEENNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
>Mature_449_residues
MEENNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=461, Percent_Identity=27.765726681128, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI186910308, Length=462, Percent_Identity=24.8917748917749, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI186910306, Length=462, Percent_Identity=24.8917748917749, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI186910304, Length=462, Percent_Identity=24.8917748917749, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI115648063, Length=448, Percent_Identity=24.5535714285714, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI115648022, Length=448, Percent_Identity=24.5535714285714, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI71979932, Length=367, Percent_Identity=25.6130790190736, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657683, Length=371, Percent_Identity=25.0673854447439, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI187423910, Length=369, Percent_Identity=24.6612466124661, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI7657591, Length=369, Percent_Identity=24.6612466124661, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI181337167, Length=331, Percent_Identity=25.9818731117825, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI9790235, Length=386, Percent_Identity=26.9430051813472, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4507047, Length=429, Percent_Identity=22.1445221445221, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI110347453, Length=364, Percent_Identity=25, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI258614005, Length=371, Percent_Identity=20.7547169811321, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI258614003, Length=371, Percent_Identity=20.7547169811321, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI71999149, Length=380, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367353, Length=419, Percent_Identity=32.9355608591885, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1786908, Length=430, Percent_Identity=28.6046511627907, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787890, Length=464, Percent_Identity=24.7844827586207, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790575, Length=447, Percent_Identity=28.6353467561521, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082250, Length=341, Percent_Identity=29.3255131964809, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786302, Length=408, Percent_Identity=22.3039215686275, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788480, Length=370, Percent_Identity=23.2432432432432, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789017, Length=343, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790584, Length=321, Percent_Identity=26.791277258567, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=346, Percent_Identity=21.6763005780347, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082023, Length=344, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=336, Percent_Identity=22.6190476190476, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=361, Percent_Identity=24.6537396121884, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17532491, Length=430, Percent_Identity=22.3255813953488, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982612, Length=366, Percent_Identity=24.5901639344262, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71982608, Length=374, Percent_Identity=24.5989304812834, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=344, Percent_Identity=23.8372093023256, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71990446, Length=376, Percent_Identity=23.6702127659574, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71995382, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995388, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=367, Percent_Identity=22.6158038147139, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=367, Percent_Identity=25.0681198910082, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17533459, Length=462, Percent_Identity=22.7272727272727, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531343, Length=362, Percent_Identity=20.7182320441989, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71982623, Length=279, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=361, Percent_Identity=23.2686980609418, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=361, Percent_Identity=23.2686980609418, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321492, Length=361, Percent_Identity=20.7756232686981, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=24.1545893719807, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=24.1545893719807, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667468, Length=407, Percent_Identity=24.3243243243243, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24641993, Length=367, Percent_Identity=25.3405994550409, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641995, Length=367, Percent_Identity=25.3405994550409, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221331183, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17647653, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24664379, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357367, Length=459, Percent_Identity=24.8366013071895, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24668806, Length=418, Percent_Identity=22.9665071770335, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356285, Length=418, Percent_Identity=22.9665071770335, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24668802, Length=418, Percent_Identity=22.9665071770335, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550968, Length=461, Percent_Identity=23.644251626898, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19921172, Length=461, Percent_Identity=23.644251626898, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24651635, Length=364, Percent_Identity=23.9010989010989, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651633, Length=364, Percent_Identity=23.9010989010989, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281366235, Length=375, Percent_Identity=24.8, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116007820, Length=375, Percent_Identity=24.8, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116007818, Length=376, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI85725152, Length=376, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48452; Mature: 48452

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LSFARLGSKIPKTGGPYQYAKIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCE
VLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITIFKLGVFLVFVIIGFANFNPQ
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTA
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RISYAAAVDGMFPQAFAKIHPKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLA
HHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLIGFIYAIWAVYGTGAESALYG
HHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
HHHHHHCCCEEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure
MEENNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LSFARLGSKIPKTGGPYQYAKIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCE
VLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITIFKLGVFLVFVIIGFANFNPQ
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTA
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RISYAAAVDGMFPQAFAKIHPKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLA
HHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLIGFIYAIWAVYGTGAESALYG
HHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
HHHHHHCCCEEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]