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The map label for this gene is pepQ [C]

Identifier: 153937353

GI number: 153937353

Start: 2096994

End: 2098082

Strand: Direct

Name: pepQ [C]

Synonym: CLC_1976

Alternate gene names: 153937353

Gene position: 2096994-2098082 (Clockwise)

Preceding gene: 153937345

Following gene: 153934855

Centisome position: 55.76

GC content: 33.15

Gene sequence:

>1089_bases
ATGGATATAAATAAACTGAACAGAGTATTAAAATCTATGAAAGAACATGACATTCCACAAATGATTATCTCTGATCCCAC
AGCTATTTTTTATTTAACAGGAAAATGGATTATTCCGGGAGAAAGATTATTAGCATTATACTTAAATGTTAATGGAAACC
ACAAAATTGTTATTAATGAACTGTTCCCACAGGAAGAAGATCTTGGTGTAGAAATCGTATGGTACAACGATATTCAAGAT
GGAGTTGAAATTTTATCTAAATTTGTAGAGAAAAATAAAGTTATAGGTATCGATAAAGTATGGCCATCTAAATTCTTATT
AAGATTACAAGAACTTGGGGGCGGAAGCAAATTTGTAAACGGTTCCTTTATTGTTGACTATGTAAGAATGATTAAAGATG
AAGAAGAAATCGCTATTTTGAGAGAATCATCAAGATTAAATGACCTTGTAATTGATGAATTGATTCCATGGGTAGGAAAA
GGTTTATCTGAAAAAGAATTAAATACTAAGGTTCGTGAAATTTACAAAAAACATGGTATTAATGAAGTATCTTTCGACCC
TATTACAGCATATGCTAAGGGAGCAGCAGATCCACACCATGTAACAGATGATACAAAAGGAAAATATGGTGACTGCGTTA
TCCTTGATATTGGAGGATTCTACAAAAACTATGCTTCTGATATGACAAGAACTGTATTTATCGGTGAAGTTTCTGAAAGA
CAAAAAGAAATCTATGACATAGTTGTAGAAGCAAACTTAAGAGGTATTGCTGCTGCAAAGCCTGGAAATAGAATGTGTGA
CGTAGACTTAGCTGCAAGAAACTATATTGAAGAAAAAGGATACGGAAAATATTTCACACACAGAACAGGACATTCCTGCG
GCTTAGAAGATCATGAATTCGGTGATGTTTCTTCTGTAAATGAAGATATCATCAAGCCAGGACAATGTTTCTCTGTTGAA
CCAGGAATTTATCTTCCAGAAGAAGGAATAGGTGTTCGTATTGAAGACCTTGTTATCACAACTGAAGATGGTTGCGAGGT
ATTAAATAAATATACAAAGGACTTAATTGTTGTTCCTGAATCCAAATAA

Upstream 100 bases:

>100_bases
AAAATAATTTATTGCAATAATTCTAGTATCTTCATTGACATTTGTAGACAAGCATATTATTATATTAGTATTTAATAACT
AAATATAGGAGGGAATACCT

Downstream 100 bases:

>100_bases
AGATAAAGAAATTGGTTAAAAATTTCTATGAAACTTTTAACAACTAAAACTTATTACAAAATATAGATAAGGAGATTGAT
TATGAAAATTACCGAAGGTT

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKNKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNKYTKDLIVVPESK

Sequences:

>Translated_362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKNKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNKYTKDLIVVPESK
>Mature_362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKNKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNKYTKDLIVVPESK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI149589008, Length=313, Percent_Identity=25.2396166134185, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI260593665, Length=313, Percent_Identity=25.2396166134185, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI93141226, Length=303, Percent_Identity=26.4026402640264, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788728, Length=241, Percent_Identity=38.5892116182573, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789275, Length=282, Percent_Identity=28.0141843971631, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17508215, Length=371, Percent_Identity=25.3369272237197, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320922, Length=238, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=21.3559322033898, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920384, Length=260, Percent_Identity=27.3076923076923, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=25.4032258064516, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40850; Mature: 40850

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINE
CCHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECCEECCCCEEEEEEEEECCCCEEEEEE
LFPQEEDLGVEIVWYNDIQDGVEILSKFVEKNKVIGIDKVWPSKFLLRLQELGGGSKFVN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEC
GSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGKGLSEKELNTKVREIYKKHGI
CHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
NEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEECHHHH
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEF
HHHHHHEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GDVSSVNEDIIKPGQCFSVEPGIYLPEEGIGVRIEDLVITTEDGCEVLNKYTKDLIVVPE
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCEEEEEC
SK
CC
>Mature Secondary Structure
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINE
CCHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECCEECCCCEEEEEEEEECCCCEEEEEE
LFPQEEDLGVEIVWYNDIQDGVEILSKFVEKNKVIGIDKVWPSKFLLRLQELGGGSKFVN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEC
GSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGKGLSEKELNTKVREIYKKHGI
CHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
NEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEECHHHH
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEF
HHHHHHEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GDVSSVNEDIIKPGQCFSVEPGIYLPEEGIGVRIEDLVITTEDGCEVLNKYTKDLIVVPE
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCEEEEEC
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]