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The map label for this gene is fur [H]

Identifier: 153937188

GI number: 153937188

Start: 2852658

End: 2853125

Strand: Direct

Name: fur [H]

Synonym: CLC_2707

Alternate gene names: 153937188

Gene position: 2852658-2853125 (Clockwise)

Preceding gene: 153936220

Following gene: 153936200

Centisome position: 75.86

GC content: 22.01

Gene sequence:

>468_bases
ATGTCAAAAGAATTAGAATTTTATAAACATATTTTTAACTCTAATAATATCAGGCTTACAACTAGACGAATTATAATTTT
AAAAATTTTCTTAAATCATAAAGATAACCATTTAACAGTAAATGAAATTTATTGTTTAGCTAAAGAAACTTACCCATCAA
TTAGTTTAGCTACTGTTTATAGAACTATTAAAACATTACTAAAACTAGATTTATTAGACCATCTCTCACTTGAAGATGGG
GGTAACCGTTATAAATTATTTGTAAATAAGAACATAAATCTCAAAGCTTATAATAAACATCATTCTCATCTTATTTGCCT
TAATTGTAAAAAAATTATAGATTGTCACTATAATTTTATAGATACTATTAAAACTGAGATAAATAAAAATTGTTTATTTA
AAATTACTGGCTTTGAAATGAAGTTTTATGGATATTGCGAAAAATGTTATATTAAAAAGGTTAAGTAA

Upstream 100 bases:

>100_bases
TATAGATGTATCTATTAATATTAAACCATTATTAATAGATAATACACATATTTATATCAAGTTATTTATTACTTAACATT
ACCTTTTAAGGAGAATTTAT

Downstream 100 bases:

>100_bases
TTATTAAATTTAAGATTTATTAAAATCATATATTTTTAGCTATAAAATTATATAATTTATATTTATGTAATATATTTACA
ATTTTATAATAAGAATTTAC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSKELEFYKHIFNSNNIRLTTRRIIILKIFLNHKDNHLTVNEIYCLAKETYPSISLATVYRTIKTLLKLDLLDHLSLEDG
GNRYKLFVNKNINLKAYNKHHSHLICLNCKKIIDCHYNFIDTIKTEINKNCLFKITGFEMKFYGYCEKCYIKKVK

Sequences:

>Translated_155_residues
MSKELEFYKHIFNSNNIRLTTRRIIILKIFLNHKDNHLTVNEIYCLAKETYPSISLATVYRTIKTLLKLDLLDHLSLEDG
GNRYKLFVNKNINLKAYNKHHSHLICLNCKKIIDCHYNFIDTIKTEINKNCLFKITGFEMKFYGYCEKCYIKKVK
>Mature_154_residues
SKELEFYKHIFNSNNIRLTTRRIIILKIFLNHKDNHLTVNEIYCLAKETYPSISLATVYRTIKTLLKLDLLDHLSLEDGG
NRYKLFVNKNINLKAYNKHHSHLICLNCKKIIDCHYNFIDTIKTEINKNCLFKITGFEMKFYGYCEKCYIKKVK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18472; Mature: 18341

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKELEFYKHIFNSNNIRLTTRRIIILKIFLNHKDNHLTVNEIYCLAKETYPSISLATVY
CCCHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCEEEHHHEEEEECCCCCCCHHHHHH
RTIKTLLKLDLLDHLSLEDGGNRYKLFVNKNINLKAYNKHHSHLICLNCKKIIDCHYNFI
HHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCCEEEEEECHHHHHCCCHHH
DTIKTEINKNCLFKITGFEMKFYGYCEKCYIKKVK
HHHHHHCCCCEEEEEECCEEEEEEEEEEEEEEECC
>Mature Secondary Structure 
SKELEFYKHIFNSNNIRLTTRRIIILKIFLNHKDNHLTVNEIYCLAKETYPSISLATVY
CCHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCEEEHHHEEEEECCCCCCCHHHHHH
RTIKTLLKLDLLDHLSLEDGGNRYKLFVNKNINLKAYNKHHSHLICLNCKKIIDCHYNFI
HHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCCEEEEEECHHHHHCCCHHH
DTIKTEINKNCLFKITGFEMKFYGYCEKCYIKKVK
HHHHHHCCCCEEEEEECCEEEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]