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The map label for this gene is fhuG [H]

Identifier: 153937093

GI number: 153937093

Start: 764198

End: 765238

Strand: Direct

Name: fhuG [H]

Synonym: CLC_0742

Alternate gene names: 153937093

Gene position: 764198-765238 (Clockwise)

Preceding gene: 153936499

Following gene: 153935946

Centisome position: 20.32

GC content: 35.73

Gene sequence:

>1041_bases
ATGAAAGAACAACAACAAATAATTGAAGCATATAAACGTAAGATAGCTATTAGAAATACATTAATTGTAATTGGATGCAT
TTTATTACTAGTAATTTCTTTAATTATAAGTATGGATACAGGATATATTAAAATGTCTCCATTGGATGTTTTAAGGACAC
TATTTGGTAGAGGGACAGATAAAGAAAAGCTGATTTTATTTGATTTTAGATTGCCTCGTATAATTATTTCAATGCTGGTA
GGATCAGGTCTTGCTTTATCAGGATGCATAATACAGAGTATATCTAGAAATCCTCTAGCTGATCCAGGAATTTTAGGTAT
CAACGCGGGTGCTAGTTTAATGGTGATTTTATATGTATTGATCTTTAGTGCAGAATCTTTCCTATCCGTGTTTACTCTTC
CATTTTTAGCCTTAATAGGAGCCGGTGCTACAGCAGTTATAGTTTATCTTTTTTCTTATAAGCGAGATGAAGGTATCTCA
ACTATGAGACTTGTTTTAACTGGTGTGGCAGTACAGGCAGGAATTTCAGCATTAACCACTTTACTAGTGGTGAAATTGGA
TGATACACAGTATAACTTTGTGGTTGCTTGGCAGGCAGGAAGTATTTGGGGGTCCAACTGGAAGTTTGTGATGACGCTGC
TACCTTGGCTAGCTATATTAATTCCATATATACTAACAAAATCTTCTGTTATGGATATACTGACTCTTAGTGATGATATA
GCCTATGGTCTTGGTGCTTCAGTAGAAAAGGAACGTCGTAAATTACTTGCAGCGGCAGTAGCTCTTGCTGCTTCATGTGT
AGCAGTTAGTGGAAGCATTAGTTTTGTAGGTTTAATAGCACCACATTTATCAAGACGACTTGTGGGACCACGACATGGTG
TGCTTTTATCCACTAGTATACTGATTGGTGCTGTATTAGTATCTTTGGCAGATACTATTGGACGTGTTATTATTCAGCCT
TCTGAGATTCCAACAGGAATTGTAGTAGCTATTATTGGAGCACCATATTTTCTTTATCTTATTTCTAATAGTAAGAGTTG
A

Upstream 100 bases:

>100_bases
TTTTAAGTCCACCCTTTGAAACTCCTATAGGAGCTATAATTTCTCTTATTGGTGTACCATTATTTTTAAATTTGGCTCGT
AGACAAAGGAGTGGAATATG

Downstream 100 bases:

>100_bases
TTATAGGATTGTTAATAAAAATAAATATAATATATAAAAATTGTAATGGTATTAAATGCATTCTGAGTAAATCAAGTTTG
CAAATATTTTAATAATATTA

Product: ferrichrome ABC transporter, permease protein FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKEQQQIIEAYKRKIAIRNTLIVIGCILLLVISLIISMDTGYIKMSPLDVLRTLFGRGTDKEKLILFDFRLPRIIISMLV
GSGLALSGCIIQSISRNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDILTLSDDI
AYGLGASVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLISNSKS

Sequences:

>Translated_346_residues
MKEQQQIIEAYKRKIAIRNTLIVIGCILLLVISLIISMDTGYIKMSPLDVLRTLFGRGTDKEKLILFDFRLPRIIISMLV
GSGLALSGCIIQSISRNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDILTLSDDI
AYGLGASVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLISNSKS
>Mature_346_residues
MKEQQQIIEAYKRKIAIRNTLIVIGCILLLVISLIISMDTGYIKMSPLDVLRTLFGRGTDKEKLILFDFRLPRIIISMLV
GSGLALSGCIIQSISRNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDILTLSDDI
AYGLGASVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLISNSKS

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=326, Percent_Identity=37.4233128834356, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790741, Length=304, Percent_Identity=31.9078947368421, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786804, Length=331, Percent_Identity=31.1178247734139, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786805, Length=292, Percent_Identity=35.2739726027397, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=33.9222614840989, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=32.0422535211268, Blast_Score=120, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37153; Mature: 37153

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQQQIIEAYKRKIAIRNTLIVIGCILLLVISLIISMDTGYIKMSPLDVLRTLFGRGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIIISMLVGSGLALSGCIIQSISRNPLADPGILGINAGASLMVILYVL
CCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDILTLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AYGLGASVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLSRRLVGPRHGVLLSTSI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LIGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLISNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCEEEEEEECCCC
>Mature Secondary Structure
MKEQQQIIEAYKRKIAIRNTLIVIGCILLLVISLIISMDTGYIKMSPLDVLRTLFGRGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIIISMLVGSGLALSGCIIQSISRNPLADPGILGINAGASLMVILYVL
CCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDILTLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AYGLGASVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLSRRLVGPRHGVLLSTSI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LIGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLISNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]