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The map label for this gene is etfA [H]

Identifier: 153936942

GI number: 153936942

Start: 2272874

End: 2273923

Strand: Reverse

Name: etfA [H]

Synonym: CLC_2137

Alternate gene names: 153936942

Gene position: 2273923-2272874 (Counterclockwise)

Preceding gene: 153935221

Following gene: 153937678

Centisome position: 60.47

GC content: 33.81

Gene sequence:

>1050_bases
ATGGATATAAAAAAAGATTTAAGTAGTTATAAAAATGTCTGGGTAATTGCAGAACAAAGACAGGGAAAAATAACTCCTGT
AGTTATAGAGTTATTAGGAGAAGGTAGAAAAATAGCTAATGATATTGGAGTAGAATTGTGCGCAGTTTTACTTGGATATA
ATGTTGATAATTTAGCAGATGAATTAATAAAGTTTGGAGCAGACAAAGTTTATTATGCAAATGATCCATTATTAGAGAAA
TATACTACTGACGGATATGCAAAGGTCATAGTTGATGCAGTAAATGATATTAAACCAGAAATCGTGCTAATTGGTGCAAC
TCATATAGGAAGAGATTTAGCTCCTAGAATAGCATCAAATTTGGATACTGGGTTAACAGCTGACTGCACTAAGTTAGAAG
TAGATCCAGAGGATAAAAAACTTAAACAAACTCGTCCAGCCTTCGGAGGAAATATCATGGCTACAATAATATGCCCTGAT
AATAGACCTCAAATGTCTACAGTAAGACCAGGAGTTATGGATAAAGCTGTAAAGGATGAAAGTAGAAAGGGTCAAATTTT
AAAATTAAGTGCAGATTTAATTAAGGATGATATAAGAACAGAGGTTATTGAAATAGTTAAATCTAAAAAAGAGTTAGTAT
CCTTAACAGATGCCAACTTTATTGTATCCGGTGGACTTGGACTTGGAAATCCTGATGGATTTAAATTGTTAAAACAGTTA
GCCGATAGATTAGGCGGTGTAGTTGGATCCTCCCGTGCAGCTGTAGATGCCGGTTGGATTGAAAATTCCCATCAAGTAGG
TCAAACAGGAACAACTGTAAAGCCAACAGTTTATATAGCTTGCGGCATTTCAGGAGCTATACAACATTTAGCTGGTATGC
AAGAATCAGATGTTATAATTGCTATAAACAAAAATGAATCAGCTCCAATATTTGAAGTAGCAGATTACGGAATAGTAGGA
GACTTATATGATGTAGTACCTAAGTTATTGGAATTGTTAGATGATGATGATCGTATTAATAGGTTATTTGAAGAAAGCAA
AATAGTTTAA

Upstream 100 bases:

>100_bases
TAAGGGTGTTATGCTAGAAGGATCAACAGAAGAGATGGTTGAAAAACTGGTTGTAAGTTTGAAACAAAAGCATATTATAT
AAAAATGATCGGAGGGTAAT

Downstream 100 bases:

>100_bases
AATAAAATTATTTTATAAAATTATGTATTCGATACTATTTATTTTATAGTATTTTATTATAAACCTCCCTATTCTAATTT
AAAGATATTAGAATCAGGGA

Product: electron transfer flavoprotein, alpha subunit/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLADELIKFGADKVYYANDPLLEK
YTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASNLDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPD
NRPQMSTVRPGVMDKAVKDESRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQL
ADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDVIIAINKNESAPIFEVADYGIVG
DLYDVVPKLLELLDDDDRINRLFEESKIV

Sequences:

>Translated_349_residues
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLADELIKFGADKVYYANDPLLEK
YTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASNLDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPD
NRPQMSTVRPGVMDKAVKDESRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQL
ADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDVIIAINKNESAPIFEVADYGIVG
DLYDVVPKLLELLDDDDRINRLFEESKIV
>Mature_349_residues
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLADELIKFGADKVYYANDPLLEK
YTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASNLDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPD
NRPQMSTVRPGVMDKAVKDESRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQL
ADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDVIIAINKNESAPIFEVADYGIVG
DLYDVVPKLLELLDDDDRINRLFEESKIV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=329, Percent_Identity=35.8662613981763, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI189181759, Length=232, Percent_Identity=42.6724137931034, Blast_Score=169, Evalue=5e-42,
Organism=Escherichia coli, GI1787990, Length=343, Percent_Identity=30.6122448979592, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786226, Length=334, Percent_Identity=29.940119760479, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082157, Length=248, Percent_Identity=27.0161290322581, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=330, Percent_Identity=37.2727272727273, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6325261, Length=232, Percent_Identity=38.3620689655172, Blast_Score=156, Evalue=5e-39,
Organism=Drosophila melanogaster, GI17136898, Length=327, Percent_Identity=36.085626911315, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24652801, Length=327, Percent_Identity=36.085626911315, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 37873; Mature: 37873

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLAD
CCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ELIKFGADKVYYANDPLLEKYTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASN
HHHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECHHHCHHHHHHHHHC
LDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPDNRPQMSTVRPGVMDKAVKDE
CCCCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCC
SRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
ADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDVII
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEECCEEEEEECCHHHHHHHCCCCCCCEEE
AINKNESAPIFEVADYGIVGDLYDVVPKLLELLDDDDRINRLFEESKIV
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLAD
CCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ELIKFGADKVYYANDPLLEKYTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASN
HHHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECHHHCHHHHHHHHHC
LDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPDNRPQMSTVRPGVMDKAVKDE
CCCCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCC
SRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
ADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDVII
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCEECCEEEEEECCHHHHHHHCCCCCCCEEE
AINKNESAPIFEVADYGIVGDLYDVVPKLLELLDDDDRINRLFEESKIV
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA