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The map label for this gene is glvC [H]

Identifier: 153936922

GI number: 153936922

Start: 320313

End: 321884

Strand: Direct

Name: glvC [H]

Synonym: CLC_0336

Alternate gene names: 153936922

Gene position: 320313-321884 (Clockwise)

Preceding gene: 153935439

Following gene: 153937811

Centisome position: 8.52

GC content: 32.0

Gene sequence:

>1572_bases
GTGAAAGATTTAATAGTAGACAAAATGCAGATGTTCGCCAAAGCTATAATTGTTCCCGTATTATTTTTACCTATTGTAGG
TGTAATTTTGGCTTTATCTTCCATTTTAAGCAATCCATCTATTGTAGGGGAAAGTGGGCTATTAATGAACATAGGTAAAT
TCATTAGTAGTGGACTTTGGCCTATTATGACAAATTTAAGTATTATTTTCTGTGTGGGAATAGCTATGGGGTTGGCAAAA
GAAAAGAAAGCAGAAGCGGCACTAGTAGCAGTATTTTCATATTTAGTATATTTAGGGGCTAATAATCAATGGCTTACTCT
AACAGGAAAGTTAGTAAAATATAAGGTTCCAGCAGATTTATATGGAACTGGACAGACTCTACAACTAGGATTTCAAGTAA
TAGACATGGGAGTTTTTCTAGGAATGATTCTTGGTGTGGTAGTGGCAATTATTCATAATAAATATTGTAATAAGGAATTT
CCTGGAGCCTTTGGATTATATGGAAATACTAAATTAGTATTTATAGTTTTAACTCCTATTACATTAATATTAGCAGTAGT
ATTTAGTTATATTTGGCCTGTAGTAGCTGCTGGTATTAGCGCTTTAACAGGTTTTATAAATGCAGCTGGAGCTATAGGAG
TATTTTTATACGGATTTTTAAATAGATTCTTAATTCCAACTGGATTACATCATTTAATATGGACACCATTTTCTTACTCT
AACATTGGAGGAGAATTGATTATAAATGGACAAAAATACTATGGAGCTTACAATATATTCTTAGCACAGCTAACTGATCC
GGCTATAAAGGTTTTTGATCCATCAGCAAAATATTTACAGTATGGTATGGTTAAAATGTTTGGATTGGCAGGAGCAGCCT
TAGCTTTTTATAAAACATCTAAACCTGAAAACAAAGTTAAATTAAAGTCTATATTGATACCAGCAGTAGCGACATCAATA
TTAGTTGGAATCACAGAACCTCTAGAATTCACATTTTTGTTTGTAGCACCATTTTTATGGGTAGTGCACTCAGTATTGGA
TGGTATATTCGAAGCAGTAGTTTCATTATTAGGAGTTAGAACTTTTGCGGCGAATGGATTTATAGATTTTATAGCTTATA
ATTTACCAGCAGGAATCGCTAAAACTAAATGGCCTATATTCATAGCTGTTGGATTAGTACAATTAGCAGTGTATTTCTTT
GTATTTAAATTCTTAATTAAAAAATTTAATCTTAAAACTCCTGGTAGAGAGGATAAGGAAGTAAAGTTAGTAACTAAAAA
AGATTTTAAAGAAAATTTAGCTAAAGCTTCAGGAGAGGTTGCTGCATCCAAAGATTCAGATTTGGCAGGGATAGTAGTTG
AAGCCTTAGGTGGTAAAGAAAATATAGAAAGTGTTGATAATTGCTTTACACGTTTAAGGTTAAAGCTTAAAAATATAGAC
GTAGTTGATGAGACAGCTTTAAAAGGAACTGGAGCAGTTGGTGTAATAAAGAAAGGTAATAACGTTCAAGTAATATATGG
ACCAAAAGTAAATGGAATCAGAAATATAGTAGATAAATATCTGGGTAATTAA

Upstream 100 bases:

>100_bases
TAATTTTACAATTTTTTCAACTTAAATTCAAGACTTTATGTAAAAATTATAAGTTATATTTAAACAAAATAAAACTATGT
TTAAAAAGGAGATGTTATTA

Downstream 100 bases:

>100_bases
TATTAGAAAAATCCAAAACGAATTACTATTTAACTTAACTTGTTTTTTTATAAGGCTTTTGTATTTAAATAGACTAAAAA
GTTTGCTAAATTATAATCAT

Product: PTS system, glucose/glucoside family, IIBC component

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAVGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN

Sequences:

>Translated_523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAVGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN
>Mature_523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAVGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=36.223506743738, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1787343, Length=522, Percent_Identity=32.7586206896552, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1786894, Length=517, Percent_Identity=33.4622823984526, Blast_Score=218, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 56758; Mature: 56758

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEHHHHCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure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EEHHHHCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]