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The map label for this gene is aspB-2 [H]

Identifier: 153936516

GI number: 153936516

Start: 2083109

End: 2084260

Strand: Reverse

Name: aspB-2 [H]

Synonym: CLC_1961

Alternate gene names: 153936516

Gene position: 2084260-2083109 (Counterclockwise)

Preceding gene: 153935816

Following gene: 153934654

Centisome position: 55.42

GC content: 28.65

Gene sequence:

>1152_bases
ATGAAAAATAAATTTTTAGCCCATAAGTATAAAGAAAATGAAAATAATTTAATGTCAGAAACCGCTAATTTAAAAAAGAA
GTTTAAAGATATAATTGATTTAAGCTTAGGGGATCCAGATATAATAACGGATAAATCTATTATACAGACTGCTTTTAAGG
ATACAAAAAAGGGATATACCAGATATTCAGATCCGACAGGAGATAAAGAATTAATAGAGGGAATTATTAATTTTTATAAA
AAAGATTGCAATATAACTTTTAAAGAAAATGAGATTATGGCAGTGGTAGGAGCTTGTCATGGTATGTATTTAGCTCTGCA
ATCCATTATAAACCCTGGTGAGGAAGTAATAGTACATTCTCCTTATTTTACTCCATACAAAGAACAAATAGAGATGGTAG
GTGGAAAATTTATTGAATTTGAAACTCTAGAGGAGGATGAGTTTAATATAAACCCTAAAAAATTAGAAAAATTAATAAAC
AGTAAAACAAAAGCTATAGTATTAAATTCTCCTAATAATCCTACAGGTGCATTTTTTTCTAAGGAATTGTTAAAAGAAAT
AACTAAAATAGCTATAGAAAATGATTTAGTTATAATATCAGATGAGGTTTATGATGGATTTACTTATTACGAGGATTTTT
GCTCCATAGCTTCTTTAGATGGGATGAAAGAAAGAACCATAACCTTAGGTAGTTTTTCCAAGGATTTTTGTATGACTGGG
TGGAGAATTGGTTACGTAGCTGCTCCAGATTATATAATTAATACTATGAAAAATATTAATGAAGGAATATGTTTTTCTGC
TCCTACAATTTCTCAAAGAGCTGCTATATATGCTTTGAAAAATAGGGATAATATTGTAGATAAAATAAAAAAAGAATTTA
GAGAAAGAATGGAATATGCCTATAGTAGAATAGAGTCTATGCCTAAATTAAGTGCTTTTAAACCTAAAGCAGGTATATAT
ATTTTTGTAAATATAAAGAAAACAGGTAAAAGCTCTGAAGAATTTTGTGATGACTTATTAAACAAAGCTCATATAGTAGC
AATACCGGGAAAGGCCTTTGGTAAGTATGGAGAAGGCTACATAAGAATTGCTTGTACAGTAGGGTTAGAGGAATTACAGC
AAGCTTTTAATAGAATTGAAAAAATACTATAA

Upstream 100 bases:

>100_bases
CTAGAAGAGGGAACACCGGAGGATATATTTAACAATGCTAAAAATTCAAGGACAAAGGACTTTCTAAGTAAAATAATTTA
GTTTAGGGAAGGAGTATGTT

Downstream 100 bases:

>100_bases
ACAGAGTTTTTGGCTTCAGAGGGAGTATTTACTCCTGCTAAAGCTAGGAAATGGTTATCCGATGACTACCAGCTCTTTAC
TCCCACTTTGAAGAAGATGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDCNITFKENEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLDGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLSAFKPKAGIY
IFVNIKKTGKSSEEFCDDLLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELQQAFNRIEKIL

Sequences:

>Translated_383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDCNITFKENEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLDGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLSAFKPKAGIY
IFVNIKKTGKSSEEFCDDLLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELQQAFNRIEKIL
>Mature_383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDCNITFKENEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLDGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLSAFKPKAGIY
IFVNIKKTGKSSEEFCDDLLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELQQAFNRIEKIL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=387, Percent_Identity=28.1653746770026, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=387, Percent_Identity=28.1653746770026, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=317, Percent_Identity=29.3375394321767, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI56713256, Length=317, Percent_Identity=29.3375394321767, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI169881281, Length=297, Percent_Identity=29.96632996633, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=25.4641909814324, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI187936925, Length=377, Percent_Identity=24.4031830238727, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14211921, Length=377, Percent_Identity=24.4031830238727, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI149944424, Length=291, Percent_Identity=24.3986254295533, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=25.5263157894737, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786816, Length=335, Percent_Identity=23.5820895522388, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788627, Length=389, Percent_Identity=24.6786632390745, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787710, Length=303, Percent_Identity=22.4422442244224, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790797, Length=317, Percent_Identity=25.8675078864353, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788332, Length=308, Percent_Identity=21.1038961038961, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=30.0613496932515, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=421, Percent_Identity=25.41567695962, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71994476, Length=228, Percent_Identity=32.0175438596491, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=228, Percent_Identity=32.0175438596491, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=370, Percent_Identity=28.1081081081081, Blast_Score=145, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28573069, Length=283, Percent_Identity=26.5017667844523, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=283, Percent_Identity=26.5017667844523, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=283, Percent_Identity=26.5017667844523, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=283, Percent_Identity=26.5017667844523, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=370, Percent_Identity=22.7027027027027, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641770, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551451, Length=346, Percent_Identity=24.5664739884393, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43578; Mature: 43578

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYT
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEGIINFYKKDCNITFKENEIMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFS
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHH
KELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLDGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCC
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIESMPKLSAFKPKAGIYIFVNIKKTGKSSEEFCDDLLNKAHIVAIPGKAFGKYGEGY
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELQQAFNRIEKIL
EEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYT
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEGIINFYKKDCNITFKENEIMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFS
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHH
KELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLDGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCC
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIESMPKLSAFKPKAGIYIFVNIKKTGKSSEEFCDDLLNKAHIVAIPGKAFGKYGEGY
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELQQAFNRIEKIL
EEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]