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The map label for this gene is yisY [H]

Identifier: 153936272

GI number: 153936272

Start: 920616

End: 921428

Strand: Direct

Name: yisY [H]

Synonym: CLC_0894

Alternate gene names: 153936272

Gene position: 920616-921428 (Clockwise)

Preceding gene: 153935625

Following gene: 153935006

Centisome position: 24.48

GC content: 37.64

Gene sequence:

>813_bases
ATGGGTTACTATATTAGAGTAGAACCTAATGTAAAAATTTATGTAGAGGATCTTAATCCTGAGGGCAATAAGACAATCGT
GTTTCTACACGGTTGGCCTGGAAGTCATAACCTGTTTGAATATCAATTTAATCAGCTTCCGAAGATGGGATATAGGTGCG
TGGGAATAGACACAAGAGGATTCGGTAATTCAGATAAGCCTTGGAGTGGATACGGCTACGATAGATTGTCAGATGATGTT
AGGTGTGTGGTTGAAGCACTCAAGCTACATGATTTTACACTCCTAGGACATTCAACAGGAGGAGCTATGGCTATTCGATA
TATGGCTCGCCATAAAGGTCACGGAGTATCTAAACTTGCTCTTATTGATGCAGCAGCTCCTAGTCTTATCAAGCGTCCCA
ATTTCCCATATGGTTTAGAAAAAGAAGATGTAATCAAAATTATTCAGGGAACATATAATGATCGTCCTAAAATGCTGAGA
GATTTTGGCGACACATTTTTCTTTCAGCATATAACTGAACCATTCTCAGATTGGTTCTTTCAATTGGGATTGCAGGCAGC
CAGCTGGGCAACTGCGGCCATTGCAAATACTTGGATAAATGAAGTGCTGTTTTCTGATCTAGAAACAATAAATGTTCCAA
CTTTAATTATTCATGGTATTCATGATAAGGTTGTTCCATTTGAGCTTGGTGAAATACAAAATAAAATGATTAAACATTCA
AAACTTATACCATTTAAATATAGCGGTCATGGGTCCTTCTATGACCAGCGTGACAAATTTAACAAAGAACTGGTGAAATT
TATTGAAGAGTAA

Upstream 100 bases:

>100_bases
ATCGAATAATAAGGTATTTAAAAGTCGGTTCAATCATTCACAAATTATTGCTCCAGTAAATAATCTATTAATATAGCGAT
TTAATTGTTGGAGGTTATCA

Downstream 100 bases:

>100_bases
AGTTTTCGCAATGTAGAGCGTCTTAATAAAAATATTAAAAGCGAATAATTAATTTAAATACCGTATTATTCAGAAGAAGC
AGATTTTACGGTATTTTTAT

Product: non-haem haloperoxidase family protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MGYYIRVEPNVKIYVEDLNPEGNKTIVFLHGWPGSHNLFEYQFNQLPKMGYRCVGIDTRGFGNSDKPWSGYGYDRLSDDV
RCVVEALKLHDFTLLGHSTGGAMAIRYMARHKGHGVSKLALIDAAAPSLIKRPNFPYGLEKEDVIKIIQGTYNDRPKMLR
DFGDTFFFQHITEPFSDWFFQLGLQAASWATAAIANTWINEVLFSDLETINVPTLIIHGIHDKVVPFELGEIQNKMIKHS
KLIPFKYSGHGSFYDQRDKFNKELVKFIEE

Sequences:

>Translated_270_residues
MGYYIRVEPNVKIYVEDLNPEGNKTIVFLHGWPGSHNLFEYQFNQLPKMGYRCVGIDTRGFGNSDKPWSGYGYDRLSDDV
RCVVEALKLHDFTLLGHSTGGAMAIRYMARHKGHGVSKLALIDAAAPSLIKRPNFPYGLEKEDVIKIIQGTYNDRPKMLR
DFGDTFFFQHITEPFSDWFFQLGLQAASWATAAIANTWINEVLFSDLETINVPTLIIHGIHDKVVPFELGEIQNKMIKHS
KLIPFKYSGHGSFYDQRDKFNKELVKFIEE
>Mature_269_residues
GYYIRVEPNVKIYVEDLNPEGNKTIVFLHGWPGSHNLFEYQFNQLPKMGYRCVGIDTRGFGNSDKPWSGYGYDRLSDDVR
CVVEALKLHDFTLLGHSTGGAMAIRYMARHKGHGVSKLALIDAAAPSLIKRPNFPYGLEKEDVIKIIQGTYNDRPKMLRD
FGDTFFFQHITEPFSDWFFQLGLQAASWATAAIANTWINEVLFSDLETINVPTLIIHGIHDKVVPFELGEIQNKMIKHSK
LIPFKYSGHGSFYDQRDKFNKELVKFIEE

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Drosophila melanogaster, GI24649021, Length=273, Percent_Identity=22.7106227106227, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 30928; Mature: 30796

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYYIRVEPNVKIYVEDLNPEGNKTIVFLHGWPGSHNLFEYQFNQLPKMGYRCVGIDTRG
CCEEEEECCCEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCEEEEEECCC
FGNSDKPWSGYGYDRLSDDVRCVVEALKLHDFTLLGHSTGGAMAIRYMARHKGHGVSKLA
CCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCCCCCCEE
LIDAAAPSLIKRPNFPYGLEKEDVIKIIQGTYNDRPKMLRDFGDTFFFQHITEPFSDWFF
EEHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLGLQAASWATAAIANTWINEVLFSDLETINVPTLIIHGIHDKVVPFELGEIQNKMIKHS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
KLIPFKYSGHGSFYDQRDKFNKELVKFIEE
CCCCEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYYIRVEPNVKIYVEDLNPEGNKTIVFLHGWPGSHNLFEYQFNQLPKMGYRCVGIDTRG
CEEEEECCCEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCEEEEEECCC
FGNSDKPWSGYGYDRLSDDVRCVVEALKLHDFTLLGHSTGGAMAIRYMARHKGHGVSKLA
CCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCCCCCCEE
LIDAAAPSLIKRPNFPYGLEKEDVIKIIQGTYNDRPKMLRDFGDTFFFQHITEPFSDWFF
EEHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLGLQAASWATAAIANTWINEVLFSDLETINVPTLIIHGIHDKVVPFELGEIQNKMIKHS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
KLIPFKYSGHGSFYDQRDKFNKELVKFIEE
CCCCEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]