Click here to switch to the map view.

The map label for this gene is walR [H]

Identifier: 153935783

GI number: 153935783

Start: 861350

End: 862063

Strand: Direct

Name: walR [H]

Synonym: CLC_0842

Alternate gene names: 153935783

Gene position: 861350-862063 (Clockwise)

Preceding gene: 153935093

Following gene: 153934959

Centisome position: 22.9

GC content: 26.89

Gene sequence:

>714_bases
GTGACAAAAATATTATTAGTAGAAGATGATATGGCTTTAGCCATTGGAGTGGAATATACATTAAAACAAGAAAATTATGA
AGTTAAAAGAGCTAAAAATTTAAAAGAGGCTAGAGATATTTTAAGAGAAGAAGAATTAGATTTAATTTTATTAGATTTAA
TGTTACCAGATGGAAGTGGATATGATTTTTGTAGTGAAGTAAGAAAAGAAAGTCTAATTCCAGTAATATTTATGACTGCC
TGTGATGAAGAAGCTAATGTGGTTTTAGGATTAGACATGGGAGGCGATGACTATATAACAAAACCTGTTAGAATAAAAGA
ACTTTTATCTAGAATAAAGGCAGTTTTAAGAAGAAGAAGTAAAGAAACAGAATCAAAAAATAATAATATAAAAGAAGATA
ATATAAAAAATAATAAAATAATTTCCAAGGACATAATAATAGAGCCTTTAAAGGCAAAAGTTTTCAAAGGAGAGGAAGAA
ATTTTATTAACAGCAGGGGAATATAAATTACTTTTAATATTATTAGAAAACAAAGGGAATGTGTTATCTAGGAATATTTT
ATTAGAAAAAATTTGGGATGTGGATGGAAGTTTTGTAGATGGAAACACATTAAATGTTTATATAAAAAGGTTAAGAGAAA
AAATAGAAAAAGATCCTAAAAAGCCTAAATATATAGAAACTGTAAGGGGAATAGGCTATAGGTGGAGTGAGTAA

Upstream 100 bases:

>100_bases
AGAAATAGGTTCTTTTTTTATACTAAAATGTTAAATTATTTTTATTTTAAATAACTATAGTATAAATTATAATTAAATAA
GTAATGTTAGGGGGGATTTT

Downstream 100 bases:

>100_bases
AATTGGTTTATGAGAGTGTAAAGCAATCTGTGTAAACTCCACTTAAAATCTTAACTCAGTGCAAAGTAGATTGTGGAATT
TTCAGTAGATAGTTACTACA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEARDILREEELDLILLDLMLPDGSGYDFCSEVRKESLIPVIFMTA
CDEEANVVLGLDMGGDDYITKPVRIKELLSRIKAVLRRRSKETESKNNNIKEDNIKNNKIISKDIIIEPLKAKVFKGEEE
ILLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEKDPKKPKYIETVRGIGYRWSE

Sequences:

>Translated_237_residues
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEARDILREEELDLILLDLMLPDGSGYDFCSEVRKESLIPVIFMTA
CDEEANVVLGLDMGGDDYITKPVRIKELLSRIKAVLRRRSKETESKNNNIKEDNIKNNKIISKDIIIEPLKAKVFKGEEE
ILLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEKDPKKPKYIETVRGIGYRWSE
>Mature_236_residues
TKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEARDILREEELDLILLDLMLPDGSGYDFCSEVRKESLIPVIFMTAC
DEEANVVLGLDMGGDDYITKPVRIKELLSRIKAVLRRRSKETESKNNNIKEDNIKNNKIISKDIIIEPLKAKVFKGEEEI
LLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEKDPKKPKYIETVRGIGYRWSE

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=34.8936170212766, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=36.9747899159664, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=35.3448275862069, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=33.9055793991416, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=35.3448275862069, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=32.7586206896552, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=31.4655172413793, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=32.034632034632, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789402, Length=236, Percent_Identity=31.7796610169492, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790863, Length=242, Percent_Identity=30.5785123966942, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=237, Percent_Identity=29.957805907173, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.3030303030303, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=30.4721030042918, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=29.535864978903, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27317; Mature: 27186

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEARDILREEELDLILLDLMLPDGSG
CCEEEEEECCCEEEEEEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCC
YDFCSEVRKESLIPVIFMTACDEEANVVLGLDMGGDDYITKPVRIKELLSRIKAVLRRRS
CHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KETESKNNNIKEDNIKNNKIISKDIIIEPLKAKVFKGEEEILLTAGEYKLLLILLENKGN
HHHHHCCCCCCCCCCCCCEEECHHHEEECHHHHHCCCCCEEEEEECCEEEEEEEEECCCC
VLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEKDPKKPKYIETVRGIGYRWSE
EEHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEARDILREEELDLILLDLMLPDGSG
CEEEEEECCCEEEEEEEEEEECCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCC
YDFCSEVRKESLIPVIFMTACDEEANVVLGLDMGGDDYITKPVRIKELLSRIKAVLRRRS
CHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KETESKNNNIKEDNIKNNKIISKDIIIEPLKAKVFKGEEEILLTAGEYKLLLILLENKGN
HHHHHCCCCCCCCCCCCCEEECHHHEEECHHHHHCCCCCEEEEEECCEEEEEEEEECCCC
VLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEKDPKKPKYIETVRGIGYRWSE
EEHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA