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The map label for this gene is cssR [H]

Identifier: 153935658

GI number: 153935658

Start: 340264

End: 340941

Strand: Direct

Name: cssR [H]

Synonym: CLC_0354

Alternate gene names: 153935658

Gene position: 340264-340941 (Clockwise)

Preceding gene: 153934789

Following gene: 153936434

Centisome position: 9.05

GC content: 28.17

Gene sequence:

>678_bases
ATGGGAAGAAAAGTCTATCTTGTTGAAGATGAAAAAAGTCTGAATATATTATTAGAAAAGTATCTACAACGTGAAGGGTA
TGAAGTAACTACTTTTTTTAATGGAAGTTCTGCAATAGAGAAAATAAAAGATGTTCCAGATATTTGGATATTAGATATAA
TGTTACCTGATATAGATGGATATCAAATAATTAAAGCTGTAAAAGAAAACAATAAAAGTACTCCAGTTATCTTTATGTCT
GCGAGGAATGAGGAACTGGATAGAGTAGTGGGATTAGAATTAGGAAGTGATGATTATTTATCAAAGCCATTCTTACCTAG
AGAGCTTATAATAAGAACTAATAAGCTTATGGAAAGAATTTATGGGAAAAGTAATAATAGTACTGTAGATATAATTACAA
ATATTGGGCAGTACAAAATAAGTAAAAAGCAAAGAACTGTTTTTTTCGAAGAAAAAGAAATTCAACTAACAAATAAAGAG
TTTGAACTATTAAATTTTTTTATAGAGAATAAAAACAATGTTATATCTAGAGAGCAAATTTTAATTAGTATTTGGGGAGA
GGATTATTTCGGATCCGATAGAGTTATTGATGATACAATTAGGAGATTGCGCAAAAAGATGGATAAGTTAGATCTTGAAA
CTGTATATGGATATGGTTATAAATTGGTGGTTAAATGA

Upstream 100 bases:

>100_bases
TTACTAATGTCATAGATGTAAAGCAAATGGCGACTGTAAAATTAAAAATAGGGTTTAATGGATAAACTAAAATACTGGAT
TATATTTTGAGGTGATAAAG

Downstream 100 bases:

>100_bases
TGAAGAGATTAAGATTTAAATCATTAACAATGAGGATATGGACAACATTCACTGCTATAATTTTAATAATAATATGTAGT
ATTTCATTTTTATATTTAGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIEKIKDVPDIWILDIMLPDIDGYQIIKAVKENNKSTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKE
FELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Sequences:

>Translated_225_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIEKIKDVPDIWILDIMLPDIDGYQIIKAVKENNKSTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKE
FELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
>Mature_224_residues
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIEKIKDVPDIWILDIMLPDIDGYQIIKAVKENNKSTPVIFMSA
RNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEF
ELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=36.6071428571429, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=34.3347639484979, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=31.5789473684211, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.0175438596491, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.8947368421053, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.7826086956522, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.920704845815, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=30.4545454545455, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=30.7017543859649, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=29.6137339055794, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=30.1801801801802, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=28.3783783783784, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=211, Percent_Identity=29.3838862559242, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26415; Mature: 26284

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIEKIKDVPDIWILDIMLPDIDG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKSTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEFELLNFFIENKNNVISREQI
HCCCCCCEEEEEECCCCEEECCCCEEEEEECCEEEECCHHHHHHHHHHHCCCCEECCEEE
LISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC
>Mature Secondary Structure 
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIEKIKDVPDIWILDIMLPDIDG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKSTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEFELLNFFIENKNNVISREQI
HCCCCCCEEEEEECCCCEEECCCCEEEEEECCEEEECCHHHHHHHHHHHCCCCEECCEEE
LISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]