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The map label for this gene is aspB-3 [H]

Identifier: 153935455

GI number: 153935455

Start: 2370798

End: 2371991

Strand: Reverse

Name: aspB-3 [H]

Synonym: CLC_2245

Alternate gene names: 153935455

Gene position: 2371991-2370798 (Counterclockwise)

Preceding gene: 153936912

Following gene: 153935791

Centisome position: 63.08

GC content: 29.65

Gene sequence:

>1194_bases
ATGAAATTATCTAAAAAAGCAATAGAAATACAACCATCTTTAACATTAGAAATAACTGCGAAAGCTAAAAAAATGAAAGC
AGAAGGTATAGATGTTATAGGTTTTGGAGCGGGAGAGCCGGATTTTAACACACCAGAGAATATACAAAAAGCAGCTATGT
TAGCCATAGAAGAAGGATATACTAAATATACCGCAGCTTCAGGTATATTAGAATTAAAACAGGCTATAGTAGATAAATTT
AAAAAAGACAATGGTTTAAACTATGAAACTAGTGAAATAATAGTAAGTAATGGAGCAAAGCAATGTCTTTCAAATTTATT
TGAAGCCATATTAAATGAAGGAGATGAGATTTTAATAGCTAAACCTTATTGGGTAAGCTATCCAGAACTTATAAAACTAT
ATGGTGGAGTACCTATTTTTGTAGATACAAAAGAAGAAAATCATTTTAAATATGAAATAGAAGAATTAGAAAATAAAGTA
ACAGATAAAACAAAGGCCATCATAATAAACAGCCCTAACAATCCTACAGGAACAGTATATAGCAAAGAAGATTTAGAAGG
CTTAGCTATTTTTGCCAAAAAACATGATTTATTAATAATAGCAGATGAAATATACGAAATGTTAATGTATGGAGAAGAAA
ATCATATAAGTATAGCAAGTTTATCAGAGGATGCTTTTAAAAGGACTGTAGTAATAAATGGTATGTCTAAATCCTATTCC
ATGACCGGCTGGAGAATAGGATATGCAGCGGGTCCTTTGGATATAATAAAAGTGATGAGTAATATACAAAGCCATACCAC
ATCTAATCCAAACTCTATAGCTCAATATGCATCCTTAGAAGCTCTTAAAGGAGATAAAACTCAGGTTAAAAATATGATAG
TGGAGTTTAAAAAGAGAAGAGATTATATGGTGAATAAAGTAAATTCTATAGGAAATTTGTCATCTACAAATCCTAAAGGA
GCTTTTTATGTAATGGTTAATATATCAAAAGCTATGGGAAAAACTATAAAAGGCAATACCATAAAGGATTCTATAAGTTT
TTCAAAAATTTTATTAGAAGAAGAAAAGGTAGCGGTAGTGCCAGGTATAGCCTTTGGTGATGATAATTTTATAAGATTAT
CCTATGCTACATCTATGGAAAATATAGAAAGAGGATTAGATAGAATAGAAAAATTCATGAAAAAATTGGATTAA

Upstream 100 bases:

>100_bases
TACTGGAAGCTATTTTAAGTAATTATTAAAATTAAACTTATGAGCAATAAATTTAGTAATAATTTATTTTAAATTTAGAA
TAAAAAGTGGAGGCAAAAAT

Downstream 100 bases:

>100_bases
TAATATCATGTAATGGTTTATAAAAACTGTTGAAATCTGTAGAAAAAAATGGTATAATATTACGTATATGTTTTTTAAGA
AACAGATAGATTATAAAAGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEGLAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRRDYMVNKVNSIGNLSSTNPKG
AFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD

Sequences:

>Translated_397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEGLAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRRDYMVNKVNSIGNLSSTNPKG
AFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
>Mature_397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEGLAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRRDYMVNKVNSIGNLSSTNPKG
AFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=319, Percent_Identity=30.0940438871473, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI169881279, Length=319, Percent_Identity=30.0940438871473, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI56713254, Length=371, Percent_Identity=27.7628032345013, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI56713256, Length=371, Percent_Identity=27.7628032345013, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI169881281, Length=230, Percent_Identity=30.8695652173913, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=23.7113402061856, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI187936925, Length=375, Percent_Identity=22.6666666666667, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI14211921, Length=375, Percent_Identity=22.6666666666667, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI149944424, Length=322, Percent_Identity=19.8757763975155, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI215599424, Length=407, Percent_Identity=21.8673218673219, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI19263340, Length=407, Percent_Identity=21.8673218673219, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7705897, Length=259, Percent_Identity=28.1853281853282, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI33469970, Length=259, Percent_Identity=28.1853281853282, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4885351, Length=372, Percent_Identity=23.6559139784946, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=25.9162303664921, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=30.5, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=27.5252525252525, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787909, Length=373, Percent_Identity=21.4477211796247, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=427, Percent_Identity=27.8688524590164, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71994472, Length=427, Percent_Identity=27.8688524590164, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=28.25, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=28.9473684210526, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71981209, Length=375, Percent_Identity=22.9333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=160, Percent_Identity=24.375, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=324, Percent_Identity=27.4691358024691, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=339, Percent_Identity=21.5339233038348, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573069, Length=421, Percent_Identity=26.8408551068884, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24646114, Length=421, Percent_Identity=26.8408551068884, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573067, Length=421, Percent_Identity=26.8408551068884, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573065, Length=421, Percent_Identity=26.8408551068884, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=23.0366492146597, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45551451, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641770, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641760, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641768, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641766, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641764, Length=365, Percent_Identity=22.4657534246575, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356535, Length=345, Percent_Identity=23.1884057971014, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44183; Mature: 44183

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGY
CCCCCCEEEECCCEEEEEECCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTAASGILELKQAIVDKFKKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHCCCCEEEEE
KPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKVTDKTKAIIINSPNNPTGTVY
CCCCCCCHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCCEE
SKEDLEGLAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
ECCCCCEEEEEEECCCEEEEHHHHHHHHHCCCCCCEEEEECCHHHHEEEEEEECCCCCCC
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRR
CCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DYMVNKVNSIGNLSSTNPKGAFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVV
HHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEE
PGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
CCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGY
CCCCCCEEEECCCEEEEEECCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTAASGILELKQAIVDKFKKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHCCCCEEEEE
KPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKVTDKTKAIIINSPNNPTGTVY
CCCCCCCHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCCCEE
SKEDLEGLAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
ECCCCCEEEEEEECCCEEEEHHHHHHHHHCCCCCCEEEEECCHHHHEEEEEEECCCCCCC
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRR
CCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DYMVNKVNSIGNLSSTNPKGAFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVV
HHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEE
PGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
CCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]