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The map label for this gene is ycbM [H]

Identifier: 153935406

GI number: 153935406

Start: 853103

End: 854008

Strand: Direct

Name: ycbM [H]

Synonym: CLC_0836

Alternate gene names: 153935406

Gene position: 853103-854008 (Clockwise)

Preceding gene: 153936577

Following gene: 153934641

Centisome position: 22.69

GC content: 24.17

Gene sequence:

>906_bases
ATGATTTTCATTATAATAGTACTAATAATTTTTTTGCTCTTTTTACTCTCCTATGTATTTTTTATGAAAAGAGAAATGAA
AAATATTACAATCCAATTAAATGAATATAATGATTTGAAATCATTAAAAAAGATAGATTCTACTCTTTTTGATAAAGAAA
TTGAAAATTTAGCTTATAGTATTAATAAACATATCGATATAAATATACAATCACAAATTAAGCAAAAGAGACTAGAAGAA
GAAATAAGAAAAAATATAGCTAATGTATCCCATGATTTGCGCACCCCCCTTACATCTATCATAGGTTATATACAAATGAT
AAAAAAAGGCAATCTATCAAAGGAAAAGCAAATAGAATATATAGACATAGCTGAAAGAAGAGCAAAGGATTTACAAAATT
TATTAAGTAATTTCTTTGAGCTTTCCATTATAGGATCACCAGATTATTATATTGAGCTTCAAAAGATTAATATAAATAAT
ATACTGTGTGAAGTAATAGCTTCTTTTTATAGTAGTTTTGTAGATAAAGATATAACTCCTAAAATAGATTTGCCAAAGGA
GAATATTATAGTGATTGGGAATGAAGGGGCTATAAAGAGGGTACTACAAAATTTAATAGTAAATATTATAAAACATTCTA
AAAGGGATGTTTATATAAGTTTTAAAAAAGAAAATAATAAAGCTGTATTAGCTACAATTAATAAATGTAATGATATTACA
GAAGATAATATAGAACTAATTTTTAATAGATTCTATAAAAAAGATGATGCCAGAACCAATAAGAATGGAAGCACTGGATT
AGGCTTATCTATTTCTAAAAGTCTTATGGAAAAAATGAATGGAGAAATTTATGCTGAAGTTCATGGGGATTTATTACATA
TTTTTTGTAAATGGAATTTAAAATAA

Upstream 100 bases:

>100_bases
GTAATCAAGATGAAAACTACTACAGTGAAATTTGGATTCCTGTTAAGAAAAAATAACTACGTAAAAGGTCATAATTTTTA
AAAAAGGGGAGAGGAGCAAT

Downstream 100 bases:

>100_bases
GAGGCTGTACTCAAAGTTGAATACAGCCTTTTGACCCTGTGTATGTAAAATATGTCTATCACAAGGTTGAATACAGCCTT
TTGACCCTGTGTATGTAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIFIIIVLIIFLLFLLSYVFFMKREMKNITIQLNEYNDLKSLKKIDSTLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQIEYIDIAERRAKDLQNLLSNFFELSIIGSPDYYIELQKININN
ILCEVIASFYSSFVDKDITPKIDLPKENIIVIGNEGAIKRVLQNLIVNIIKHSKRDVYISFKKENNKAVLATINKCNDIT
EDNIELIFNRFYKKDDARTNKNGSTGLGLSISKSLMEKMNGEIYAEVHGDLLHIFCKWNLK

Sequences:

>Translated_301_residues
MIFIIIVLIIFLLFLLSYVFFMKREMKNITIQLNEYNDLKSLKKIDSTLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQIEYIDIAERRAKDLQNLLSNFFELSIIGSPDYYIELQKININN
ILCEVIASFYSSFVDKDITPKIDLPKENIIVIGNEGAIKRVLQNLIVNIIKHSKRDVYISFKKENNKAVLATINKCNDIT
EDNIELIFNRFYKKDDARTNKNGSTGLGLSISKSLMEKMNGEIYAEVHGDLLHIFCKWNLK
>Mature_301_residues
MIFIIIVLIIFLLFLLSYVFFMKREMKNITIQLNEYNDLKSLKKIDSTLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQIEYIDIAERRAKDLQNLLSNFFELSIIGSPDYYIELQKININN
ILCEVIASFYSSFVDKDITPKIDLPKENIIVIGNEGAIKRVLQNLIVNIIKHSKRDVYISFKKENNKAVLATINKCNDIT
EDNIELIFNRFYKKDDARTNKNGSTGLGLSISKSLMEKMNGEIYAEVHGDLLHIFCKWNLK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=26.7241379310345, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=24.0601503759398, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=23.7068965517241, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=283, Percent_Identity=24.0282685512367, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788393, Length=211, Percent_Identity=26.0663507109005, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=296, Percent_Identity=25.3378378378378, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=285, Percent_Identity=21.7543859649123, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=22.7118644067797, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=205, Percent_Identity=22.4390243902439, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35001; Mature: 35001

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFIIIVLIIFLLFLLSYVFFMKREMKNITIQLNEYNDLKSLKKIDSTLFDKEIENLAYS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
INKHIDINIQSQIKQKRLEEEIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQIEY
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHH
IDIAERRAKDLQNLLSNFFELSIIGSPDYYIELQKININNILCEVIASFYSSFVDKDITP
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
KIDLPKENIIVIGNEGAIKRVLQNLIVNIIKHSKRDVYISFKKENNKAVLATINKCNDIT
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEHHCCCCC
EDNIELIFNRFYKKDDARTNKNGSTGLGLSISKSLMEKMNGEIYAEVHGDLLHIFCKWNL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEEEECC
K
C
>Mature Secondary Structure
MIFIIIVLIIFLLFLLSYVFFMKREMKNITIQLNEYNDLKSLKKIDSTLFDKEIENLAYS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
INKHIDINIQSQIKQKRLEEEIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQIEY
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHH
IDIAERRAKDLQNLLSNFFELSIIGSPDYYIELQKININNILCEVIASFYSSFVDKDITP
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
KIDLPKENIIVIGNEGAIKRVLQNLIVNIIKHSKRDVYISFKKENNKAVLATINKCNDIT
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEHHCCCCC
EDNIELIFNRFYKKDDARTNKNGSTGLGLSISKSLMEKMNGEIYAEVHGDLLHIFCKWNL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCEEEEEEEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]