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The map label for this gene is cobO [H]

Identifier: 153935290

GI number: 153935290

Start: 1027537

End: 1028058

Strand: Direct

Name: cobO [H]

Synonym: CLC_1010

Alternate gene names: 153935290

Gene position: 1027537-1028058 (Clockwise)

Preceding gene: 153936017

Following gene: 153937427

Centisome position: 27.32

GC content: 29.31

Gene sequence:

>522_bases
ATGAAAGAAGAAAAAGGATACATACAAGTTTATACAGGAAACGGTAAAGGCAAAACCACAGCAGCTTTAGGAATTTCTTT
AAGAGCAATTTGTTCTGGAAAAAAAGTTTTTTTCGGACAATTTACAAAGGGGATGAAATATAGCGAATTAAAAGCTCCAA
CAATATTACCTAATTTTACGATGGAACAGTTTGGACGAGATAAGTTTATATTTGGGAACCCAGAAGAAGAAGATATAAAA
TTAGCAAAAGAAGGACTAAAAAAAATAGAAAAAATATTAACTTCTGGTGATTATGATTTAGTTGTTATGGATGAAATTAA
TATAGCTTTATATTATGGCTTATTTACAGTAGAAGAAGTAATAGAAGTAATAGATAAAAGAAATCCAAAGATAGAGGTTA
TATTAACGGGAAGATATGCAAAAGAAGAGATAATGGAAAAAGCAGATTTAGTAACAGAAATGAAAGAAATAAAACATTAC
TACGAAAAAGGAGTTCCTGCAAGAGTAGGAATAGAAAGTTAG

Upstream 100 bases:

>100_bases
CTAATTCGTTTCGCTAAAAAGTTCTAAATATATATAGTTAGCAATAACAAGGGAAGAGCTACATTGTATAAGGAAGATAA
CGAAAAAGGCAGGTGTAATT

Downstream 100 bases:

>100_bases
AAAATATGCAAACTTATATTTTAGCACAAGGAGACACCTTTAAAATAATAACGGATATAGGTAGTGGAATTAACCATAAT
AAAAGGAATTAATTGAAGAA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKEEKGYIQVYTGNGKGKTTAALGISLRAICSGKKVFFGQFTKGMKYSELKAPTILPNFTMEQFGRDKFIFGNPEEEDIK
LAKEGLKKIEKILTSGDYDLVVMDEINIALYYGLFTVEEVIEVIDKRNPKIEVILTGRYAKEEIMEKADLVTEMKEIKHY
YEKGVPARVGIES

Sequences:

>Translated_173_residues
MKEEKGYIQVYTGNGKGKTTAALGISLRAICSGKKVFFGQFTKGMKYSELKAPTILPNFTMEQFGRDKFIFGNPEEEDIK
LAKEGLKKIEKILTSGDYDLVVMDEINIALYYGLFTVEEVIEVIDKRNPKIEVILTGRYAKEEIMEKADLVTEMKEIKHY
YEKGVPARVGIES
>Mature_173_residues
MKEEKGYIQVYTGNGKGKTTAALGISLRAICSGKKVFFGQFTKGMKYSELKAPTILPNFTMEQFGRDKFIFGNPEEEDIK
LAKEGLKKIEKILTSGDYDLVVMDEINIALYYGLFTVEEVIEVIDKRNPKIEVILTGRYAKEEIMEKADLVTEMKEIKHY
YEKGVPARVGIES

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=172, Percent_Identity=34.8837209302326, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19621; Mature: 19621

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEKGYIQVYTGNGKGKTTAALGISLRAICSGKKVFFGQFTKGMKYSELKAPTILPNFT
CCCCCCEEEEEECCCCCCEEHHHHHEEEEHHCCCEEEEEHHHCCCCCCCCCCCCCCCCCC
MEQFGRDKFIFGNPEEEDIKLAKEGLKKIEKILTSGDYDLVVMDEINIALYYGLFTVEEV
HHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHHHHHHHHH
IEVIDKRNPKIEVILTGRYAKEEIMEKADLVTEMKEIKHYYEKGVPARVGIES
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKEEKGYIQVYTGNGKGKTTAALGISLRAICSGKKVFFGQFTKGMKYSELKAPTILPNFT
CCCCCCEEEEEECCCCCCEEHHHHHEEEEHHCCCEEEEEHHHCCCCCCCCCCCCCCCCCC
MEQFGRDKFIFGNPEEEDIKLAKEGLKKIEKILTSGDYDLVVMDEINIALYYGLFTVEEV
HHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHHHHHHHHH
IEVIDKRNPKIEVILTGRYAKEEIMEKADLVTEMKEIKHYYEKGVPARVGIES
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]