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The map label for this gene is stc [H]

Identifier: 153934967

GI number: 153934967

Start: 2017920

End: 2020010

Strand: Reverse

Name: stc [H]

Synonym: CLC_1904

Alternate gene names: 153934967

Gene position: 2020010-2017920 (Counterclockwise)

Preceding gene: 153935720

Following gene: 153935809

Centisome position: 53.72

GC content: 44.0

Gene sequence:

>2091_bases
ATGAGAAAATTATGGAGGAATCATGAAGGAATCATGAAAAAAACGATGTCTGTAGTGGCTTTGGATGCCAGAGCCGGAGA
GTTTTATGCAAAAGAAATCAATGAACTGTTTGGGGAATATGTGGAGATAGCATCCTACAATGTGAGTGACGGGTCTGCCG
TGGGAACGTTGCCAAAGGCAGATTTATTTGTGATTTCAACAGATGCATATGGTTCCGCAGAAGAGGTGGCCCGCCATGTT
CCTATAGACAGCCTTACCATGGGAATTGAAGTTTCCTACCGGTGGAGTACGTTGCAAAACCTTAGTATGATACCAAAGGG
AACCCGAGCTCTTTTTGTAAATATGACAGATACCATGGCTCGAGAGGCTATTGCACAGCTGCAACAGCTGGGGGTAAACC
ATATTCGTTTTATTCCATTTTACCCAGGTGCTGTTTTGGAAGAGCCGGTGGATATGGCTGTAACGCCAGAGGAGGAGAGA
TATGTACCTCAGAGCGTAAAGAAAGTTTTAAATATCGGACACCGTTCCTGTACCTCGGGAATGATGATCGAGATTGCCTT
GCGTATGGGACTTGAACAGTTGTTAGAGACGAAAAAATTCCAAAATTATTTCCAGGCGATGGCAACGAATAATTACAGCT
TTAATCAGATATATGCCCGCTCTAGAAGACTGGAAAGCCAATTCCATATTTTAATGGAAATATTGGATGAGGGATTGGTA
GGCGTTAATGAAAAGGGGGAGATTTTTGCATGCAATAAGAAAGCCTGCCAGATTGCAAAAATTGCGGAAAATCTTGTTAT
TGGCAGGTGCGGGGAAAAAGTATTTCCCTATATTCCCTTTTACAGTGCATTGAAGGATAAGAAAGAAATTCCGCCTAAAG
TGATTAAGCTGGGTGGCGTAAACGTAAGTATTGAAGTTATACCGGTTCTGCGGCAGAAGAAATGCATCGGTGCATTTGCT
ACCCTACAGGAATTTAGTGAGCTGGAATCCAAACAGAATGAGTTAAGAAGCCAGCTTCTAAAAAAGGGTTATTGTGCCAA
GTATACCTTTAATGATGTAATCGGAGAATCAGATTGTATCTGCCATACAAAGAGTATTTTGAAACGGATGGCGGCTACCG
AAAGTCCAGTTTTAATTGTAGGTGAAACAGGAACGGGAAAAGAACTGCTGGCTCATGCGGTGCATTGTGCATCTAAGCGA
AGCAAAGGTCCTTTTATTGCCATTAATGTGGCAGCCATGCCGGAAAATCTTCTGGAAAGCGAGCTTTTCGGCTATGAAGA
GGGCGCATTTACCGGTGCGAAAAAAGGCGGACGCCCTGGGCTGTTTGAATTTGCCCATGGTGGTACCTTATTCCTCGATG
AAGTAGAAGGTATGAGCCAGGCTATGCAGGTAAAGCTTCTGAGAGTTCTGCAGGAAGGCGAAGTCATGCGTGTAGGTGGC
AGCAGAATCCTAAGTGTTGATGTTAGAATTGTTGCAGCAACCAATGAATCTTTGGAGCAGAAGGTGGAGGAAGGAAGCTT
CCGAAAGGATCTGTATTATCGTCTGAATACTTTGACGGTTGTAGTACCGCTGTTACAGGAACGGGGAGAGGATGTCTTTC
TTTTGATGGAGCATTTTAAAGAGGAGCTCCGGGGTGACTTTAAGTTATCGGAGGAAGTGAAAGACTTTCTGCGTCAGTAT
TCCTGGCCGGGAAATATCCGGGAACTGCATAACACAGTGGAATATTTTGTTTATACCGGGAAACAGGTGATTGATATGGA
TGATTTACCGCCTACTATTTTCCATGACCGGACATCCAGACCGGTGAATGTGGAGAAGAAGGAGAGACTGCAGGAGGTGG
TTTCGCCCTTCTGGTTTGTTCTGGAACAGCTTTATATGGCAGCAGAGAGGAATGAGTTTATCGGAAGGGATAAGTTGCTG
TTGAAGGCGAAGAAGCAGTATCTTCTATTGTCCCAAAAGGAGATTCGGGATATTTTAAAGGATATGGAGAAAAAAGGTTT
CGTAAAAATCGGAAAAGGAAGAGGCGGCAGCAGGATTACCTTGAAGGGGAAGGAATACTGTCAGAGTCGGGATAAGTCTT
TGGATAAGTAG

Upstream 100 bases:

>100_bases
TACATTCTTAAATGATCAAAAAGTTACATTCTAATCTAATCTTGACATTTATACAAAATTGCATTCACTTATTCTTTAAG
CTATAATAAATGTAGGTAAT

Downstream 100 bases:

>100_bases
AAAAACATATAGAAAGAAAGCAGTGCCAAGTTATAATATACTTAGCACTGCCTTTTATGAGTCTTAAATTATAGTGATAA
ATAAATTTTTTATTTATATT

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKSILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRILSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFLLMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKERLQEVVSPFWFVLEQLYMAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK

Sequences:

>Translated_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKSILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRILSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFLLMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKERLQEVVSPFWFVLEQLYMAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
>Mature_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKSILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRILSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFLLMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKERLQEVVSPFWFVLEQLYMAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=278, Percent_Identity=44.6043165467626, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789233, Length=259, Percent_Identity=44.7876447876448, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1790299, Length=250, Percent_Identity=48.8, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1790437, Length=269, Percent_Identity=47.5836431226766, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=266, Percent_Identity=43.984962406015, Blast_Score=218, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=246, Percent_Identity=47.5609756097561, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87082117, Length=266, Percent_Identity=43.984962406015, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=242, Percent_Identity=46.6942148760331, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788905, Length=254, Percent_Identity=44.8818897637795, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1789087, Length=274, Percent_Identity=41.6058394160584, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=405, Percent_Identity=31.8518518518519, Blast_Score=183, Evalue=4e-47,
Organism=Escherichia coli, GI87081858, Length=406, Percent_Identity=26.3546798029557, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789828, Length=302, Percent_Identity=31.7880794701987, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 78731; Mature: 78731

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCH
CHTKSILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRILSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFLLMEHFK
CEEEEEEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
EELRGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEECCCCCCHHCCCCCCC
PVNVEKKERLQEVVSPFWFVLEQLYMAAERNEFIGRDKLLLKAKKQYLLLSQKEIRDILK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC
>Mature Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCH
CHTKSILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRILSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFLLMEHFK
CEEEEEEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
EELRGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEECCCCCCHHCCCCCCC
PVNVEKKERLQEVVSPFWFVLEQLYMAAERNEFIGRDKLLLKAKKQYLLLSQKEIRDILK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA