Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 153933291

GI number: 153933291

Start: 3468131

End: 3469327

Strand: Reverse

Name: etfA [H]

Synonym: CLB_3342

Alternate gene names: 153933291

Gene position: 3469327-3468131 (Counterclockwise)

Preceding gene: 153933810

Following gene: 153931813

Centisome position: 89.8

GC content: 32.33

Gene sequence:

>1197_bases
ATGGCTATCAAAATTATTAAAGAAAAATGTAAAGCATGTGGTATATGTGAAAAGCAATGCCCATTTGATGCTATTCATGT
AGTTAACGGATTAGCAGAAGTAAATGAAAAATGTACAATATGTGGAGCCTGCGTAGAAGCTTGCCCATTTGATGCAATAG
AAAAAGAAGAGAAGAAAGTTGTAAAAAAGGATATTAGTAAATATAAAGGTGTATGGGTATACGCTGAACAAAGACAAGGA
GAACTTACTCCAGTAGTAATAGAATTATTAGGAGAAGGTAAAAAATTAGCTAATGAAATAGGAACAGATTTATCTGCAAT
TTTATTAGGAGATAATGTAGGATCACTAGCAGAAGAATTAATAAAGTATGGAGCAAATAAAGTATATGTAGCGGATGATA
AAAAATTAGAAAATTATACAACAGATGCTTATACTACAGTGATTTCAAATGCTATAGATCAATATAAGCCAGAATCAGTT
TTATTTGGTGCAACTCATATTGGAAGAGACTTAGCGCCTAGAATTGCAGCAAGAGTTGATACTGGACTTACAGCTGATTG
TACAAAATTAGAGATAGATCCTGAAGCGAAAAACGTAAAACAAACTAGACCTGCATTTGGTGGAAACTTAATGGCAACTA
TAGTATGTAAGAACCATAGACCACAAATGTCTACAGTAAGACCTGGTGTTATGGAGAAAGCAAAATACAATGAAGACAAT
AAAGGTGAAATAATAGATATAAAAGTAGCATTAAGTGAAGATGAGATTAGAACTAAAGTTTTAGAGATAATCAAGTCTTC
TAAAAAACAAGTTTCTTTAGTTGATGCAGACTTTATCGTATCTGGTGGTAAGGGACTTGGAAATCCAGATGGATTTAAGT
TATTAAAAGAGTTAGCTGATTTATTAGGTGGAGTAGTTGGTAGTAGCCGTGCTGCAGTTGATATAGGATGGATAGAACAT
TCACATCAAGTTGGACAAACTGGAACAACTGTAAAACCTGTTATTTATATTGCATGTGGTATATCAGGAGCTATCCAACA
CGTTGCTGGTATGTCAAATTCTGATATAATAATTGCTATAAATAAAGATGAAAATGCACCTATATTTGAAATAGCTGATT
ACGGAATTGTTGGAGACTTATATGAAATAGTTCCAATACTAATAGAAGAAGTGAAAAAAATTAAACAAGAAGACTAA

Upstream 100 bases:

>100_bases
CACAAGGTGTTATATTAGAAGGAACAGCTAAAGAAAAGGTAGAAAAATTAGTATCAGCACTTCAATCTAAACACTATATT
TAAGTTTTGGGAGGTTTATT

Downstream 100 bases:

>100_bases
GAAGGTTAATTAATTTACTTGCAAGAAACAAAATGAGGTTTTCCTCCTTTTGTTTCTTGTATATATTTTTAATAAATAGT
TAAAAAAATAACAATCTAAG

Product: electron transfer flavoprotein, alpha subunit/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQG
ELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESV
LFGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
KGEIIDIKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEH
SHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPILIEEVKKIKQED

Sequences:

>Translated_398_residues
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQG
ELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESV
LFGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
KGEIIDIKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEH
SHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPILIEEVKKIKQED
>Mature_397_residues
AIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQGE
LTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVL
FGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDNK
GEIIDIKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEHS
HQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPILIEEVKKIKQED

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=334, Percent_Identity=34.4311377245509, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI189181759, Length=286, Percent_Identity=37.0629370629371, Blast_Score=165, Evalue=6e-41,
Organism=Escherichia coli, GI1787990, Length=332, Percent_Identity=30.421686746988, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786226, Length=333, Percent_Identity=30.6306306306306, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082157, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=331, Percent_Identity=38.368580060423, Blast_Score=191, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6325261, Length=311, Percent_Identity=31.5112540192926, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17136898, Length=335, Percent_Identity=36.4179104477612, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24652801, Length=335, Percent_Identity=36.4179104477612, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 43118; Mature: 42987

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VKKDISKYKGVWVYAEQRQGELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEEL
HHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
IKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVLFGATHIGRDLAPRIAARVD
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHC
TGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
CCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCCC
KGEIIDIKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELAD
CCCEEEEEEEECHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHH
LLGGVVGSSRAAVDIGWIEHSHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAI
HHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEE
NKDENAPIFEIADYGIVGDLYEIVPILIEEVKKIKQED
ECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKV
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VKKDISKYKGVWVYAEQRQGELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEEL
HHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
IKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVLFGATHIGRDLAPRIAARVD
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHC
TGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
CCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCCC
KGEIIDIKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELAD
CCCEEEEEEEECHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHH
LLGGVVGSSRAAVDIGWIEHSHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAI
HHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEE
NKDENAPIFEIADYGIVGDLYEIVPILIEEVKKIKQED
ECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA