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The map label for this gene is fruR [H]

Identifier: 153932251

GI number: 153932251

Start: 2293435

End: 2294193

Strand: Reverse

Name: fruR [H]

Synonym: CLB_2149

Alternate gene names: 153932251

Gene position: 2294193-2293435 (Counterclockwise)

Preceding gene: 153933530

Following gene: 153931304

Centisome position: 59.38

GC content: 27.4

Gene sequence:

>759_bases
ATGCTTCCAGTAGAGAGAGAACAATACATAATTGAAAAGCTAGAAGATCTAGGAACTGTAAAAGTTGAAGATATTGCTAA
TGAACTAAATGTAAGTTTAATGACTATAAGAAGAGATTTTGATAGATTACAGGATAAAGGTATTTTATATAGGAGTCATG
GAGGAGCTGTAAAACGATCTACTTATTTATCAGAACAAGCCTATGATTTAAAGAAGATAAGCAATATATATGTAAAAGAA
AAAATAGCAGAAAAAGCTTTAAGTATAATTAAAGAAGGAGACAGTATATTTTTAGATGCAGGTACTACAACTTTTGAATT
GGCTAAAGTGCTTAACAAAGTAAAAGATATAACAGTTATAACAAACGATCTTAAAATAGCTTTAGAATTGTATCAAAACA
ATGTGAAAGCTTATATAGTAGGTGGGAAAATACAAGAAGAAACAGGATGTATAATAGGTCCTACTGCAGATGAATTTATA
TCTAATATAAAAGTTAATGTAGCTTTCTTAGGAACCTCTGGCATAGATTCTGATTTTAGATTATCTACTCCTACCTTTGA
AAAGGCAAACTTAAAGAAACGTATAGTAAAATCAGCATCTTATTCTGTTCTTTTAACAGATAGTAGTAAGTTTAATAAGG
AATCCTTTGTAAATATATTTTCTATGGAATCAGTAAATTGTGTCATTACAGATAAAAAATTTGATAAAGACGAAGATAAA
TATTTAGAATCATTAAATGTAAAAATAATCAATGTATAA

Upstream 100 bases:

>100_bases
GAACAAATAAAACGAAAAGAAAAACACAAATTAAGTTTCATAAGTAAATTAGATTAATATAGATTAATTTGTTTTTATAC
TGAAAATAAGAGGTGATAGG

Downstream 100 bases:

>100_bases
ATAGGAATTTTATTCAATAAATCCTATGAAGTTTAGCAAATGATTGGTTCGAGGGGGACATTAAATGTTAAATTATGTTA
TTATAGCTGACGATTTGACG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELNVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKESFVNIFSMESVNCVITDKKFDKDEDK
YLESLNVKIINV

Sequences:

>Translated_252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELNVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKESFVNIFSMESVNCVITDKKFDKDEDK
YLESLNVKIINV
>Mature_252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELNVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKESFVNIFSMESVNCVITDKKFDKDEDK
YLESLNVKIINV

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=31.3253012048193, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=32.3275862068966, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI226510968, Length=243, Percent_Identity=30.0411522633745, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082344, Length=228, Percent_Identity=28.9473684210526, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=28.6852589641434, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=30.6382978723404, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=28.8, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790753, Length=201, Percent_Identity=32.3383084577114, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790635, Length=262, Percent_Identity=25.1908396946565, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=22.9249011857708, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28373; Mature: 28373

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVEREQYIIEKLEDLGTVKVEDIANELNVSLMTIRRDFDRLQDKGILYRSHGGAVKRS
CCCCHHHHHHHHHHHHCCCEEHHHHHHHHCEEEEEHHHHHHHHHHCCEEEECCCCCEEHH
TYLSEQAYDLKKISNIYVKEKIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCEEEE
TNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFISNIKVNVAFLGTSGIDSDFR
ECCHHHHEEEHHCCEEEEEECCEEECCCCEEECCCHHHHHHCCEEEEEEEECCCCCCCCE
LSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKESFVNIFSMESVNCVITDKKFDKDEDK
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEEEEECCEEEEEECCCCCCCHHH
YLESLNVKIINV
HHHHCCEEEEEC
>Mature Secondary Structure
MLPVEREQYIIEKLEDLGTVKVEDIANELNVSLMTIRRDFDRLQDKGILYRSHGGAVKRS
CCCCHHHHHHHHHHHHCCCEEHHHHHHHHCEEEEEHHHHHHHHHHCCEEEECCCCCEEHH
TYLSEQAYDLKKISNIYVKEKIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCEEEE
TNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFISNIKVNVAFLGTSGIDSDFR
ECCHHHHEEEHHCCEEEEEECCEEECCCCEEECCCHHHHHHCCEEEEEEEECCCCCCCCE
LSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKESFVNIFSMESVNCVITDKKFDKDEDK
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEEEEECCEEEEEECCCCCCCHHH
YLESLNVKIINV
HHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]