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The map label for this gene is degQ [H]

Identifier: 153002952

GI number: 153002952

Start: 91139

End: 92518

Strand: Reverse

Name: degQ [H]

Synonym: Anae109_0073

Alternate gene names: 153002952

Gene position: 92518-91139 (Counterclockwise)

Preceding gene: 153002953

Following gene: 153002951

Centisome position: 1.75

GC content: 74.13

Gene sequence:

>1380_bases
GTGCGCGCGCACCGCGCGATCCTCGCCTCGCTCGCGCTCGGGGCCTCCGTGCTCGCCGCGAGCGCTTCCGCCCGACCGAA
CGCCCTCCCCCGCCCCGACGAGCGTCCCTCGCCGAGCCGGCGCACGCCGGTGGTGCAGGCGGTGGAGAAGGTGCGCGGCG
CGGTGGTCAACGTCTCCGCCGAGGAGCTCGTCCGCATCCGCGTGCCGTCGCGGGCGAGCTCGATGGCGGAGCTGCTCTTC
GGCGACTTCTTCGAGAAGCCCCGCTTCCGCAAGGGCTACGCGGTGAGCTCGCTCGGCTCGGGCGTCATCGTCTCGCCCGA
CGGGTACGTGCTCACGAACAACCACGTGGTCGAGCGCGGCGCCCGCTTCCGCGTGGGCCTGCTCGACGGGCGCGAGATCA
ACGCCAAGGTGGTGGGGACCGATCCGTCGAGCGACCTCGCCGTGCTGAAGCTGGAGACGAAGGAGCGGCTCCCCTTCGCC
ACCCTGGGCCGCTCGGACGACCTCCTCATCGGCGAGACGCTCATCGCCATCGGGAACCCGTTCGGCCTCTCGCACACCGT
CACGACGGGCGTGGTCTCCGCGGTGCACCGGAACTTCCGGGCCGGCGACCGGATGCTCTTCGACTTCGTCCAGACGGACG
CCTCCATCAACCCGGGCAACTCCGGCGGCGCGCTCCTCGACATCGAGGGGCGGCTCGTCGGCATCAACACCGCCATCCTG
GGCGACCGGAACGCCGGCATCGGCTTCGCCATCCCCATCGACCGCGCGCGGCGCATCGCCGAGGACCTCATCGCGCACGG
CGAGGTGCGCGAGGGCTACGTGGGCGTGGCGGTGGACGACCTGCCCGCGAAGGACGGCGCGGCGGAGGGGGCGTCCGGCG
GGGTGGTGGTGACCGGCGTGGATCCCGGCTCACCCGCCGCGAAGGCCGGCGTGAAGAAGGGCGACGTCGTGGAGGCGGTG
CAGGGCTTCGCGGCCCGCAGCGCCGAGGAGTTCCGCTTCCGGATGCGCGATCTCCCCATCGGCCAGGCCGCGCGCCTCGA
GCTCGTCCGGGGCGGGAAGCGGATCGCCCTGTCGGTGCCGTCGGTGGAGCTCTCCCCGGAGGCCGCCGCGCAGCTCGCCA
CGCGCTCGACGGGGCTCACGCTCGCCGAGGAGCGCCTGCACCGCGGCTCGGTGCTCATCGTGAAGACCGTCGCGCCCGCC
TCGCCCGCCGCCCGGGTGGGGATCCGCCAGGGCGACCTCGTGCGCGAGGTGAACTCGACCGAGGTCGCGACGCTCGCCGA
CTTCCGCCGGGCCGCCGCCCGCGCGCGCCGGAGCGGCCAGCTCGTGCTGCTCGTGCAGCGCGGCTACGCGGCCGAGCGGA
TCGCCTTCGACTTCCAGTAG

Upstream 100 bases:

>100_bases
CGAAGCCTCGATGGACTCCGACGATCGCGACGACCTCGACGACGTCGACGACGAGCCCGAGTCGCCCGCCGACACCGGCG
AGGCCCCCCAGACCTGAGCC

Downstream 100 bases:

>100_bases
ACTCCGGGGCACAGGCCGCGTCGCGGCCCGCGCTGCGGGGAGGTCGCCATGGACGAGAAGAGCGCCGGCGGGATCGACTT
CTACACCTTCGTGCTGTCGC

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRAHRAILASLALGASVLAASASARPNALPRPDERPSPSRRTPVVQAVEKVRGAVVNVSAEELVRIRVPSRASSMAELLF
GDFFEKPRFRKGYAVSSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGREINAKVVGTDPSSDLAVLKLETKERLPFA
TLGRSDDLLIGETLIAIGNPFGLSHTVTTGVVSAVHRNFRAGDRMLFDFVQTDASINPGNSGGALLDIEGRLVGINTAIL
GDRNAGIGFAIPIDRARRIAEDLIAHGEVREGYVGVAVDDLPAKDGAAEGASGGVVVTGVDPGSPAAKAGVKKGDVVEAV
QGFAARSAEEFRFRMRDLPIGQAARLELVRGGKRIALSVPSVELSPEAAAQLATRSTGLTLAEERLHRGSVLIVKTVAPA
SPAARVGIRQGDLVREVNSTEVATLADFRRAAARARRSGQLVLLVQRGYAAERIAFDFQ

Sequences:

>Translated_459_residues
MRAHRAILASLALGASVLAASASARPNALPRPDERPSPSRRTPVVQAVEKVRGAVVNVSAEELVRIRVPSRASSMAELLF
GDFFEKPRFRKGYAVSSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGREINAKVVGTDPSSDLAVLKLETKERLPFA
TLGRSDDLLIGETLIAIGNPFGLSHTVTTGVVSAVHRNFRAGDRMLFDFVQTDASINPGNSGGALLDIEGRLVGINTAIL
GDRNAGIGFAIPIDRARRIAEDLIAHGEVREGYVGVAVDDLPAKDGAAEGASGGVVVTGVDPGSPAAKAGVKKGDVVEAV
QGFAARSAEEFRFRMRDLPIGQAARLELVRGGKRIALSVPSVELSPEAAAQLATRSTGLTLAEERLHRGSVLIVKTVAPA
SPAARVGIRQGDLVREVNSTEVATLADFRRAAARARRSGQLVLLVQRGYAAERIAFDFQ
>Mature_459_residues
MRAHRAILASLALGASVLAASASARPNALPRPDERPSPSRRTPVVQAVEKVRGAVVNVSAEELVRIRVPSRASSMAELLF
GDFFEKPRFRKGYAVSSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGREINAKVVGTDPSSDLAVLKLETKERLPFA
TLGRSDDLLIGETLIAIGNPFGLSHTVTTGVVSAVHRNFRAGDRMLFDFVQTDASINPGNSGGALLDIEGRLVGINTAIL
GDRNAGIGFAIPIDRARRIAEDLIAHGEVREGYVGVAVDDLPAKDGAAEGASGGVVVTGVDPGSPAAKAGVKKGDVVEAV
QGFAARSAEEFRFRMRDLPIGQAARLELVRGGKRIALSVPSVELSPEAAAQLATRSTGLTLAEERLHRGSVLIVKTVAPA
SPAARVGIRQGDLVREVNSTEVATLADFRRAAARARRSGQLVLLVQRGYAAERIAFDFQ

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=305, Percent_Identity=34.7540983606557, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI22129776, Length=261, Percent_Identity=36.7816091954023, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI7019477, Length=254, Percent_Identity=37.4015748031496, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI24308541, Length=262, Percent_Identity=35.4961832061069, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786356, Length=430, Percent_Identity=35.1162790697674, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789629, Length=446, Percent_Identity=35.8744394618834, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789630, Length=370, Percent_Identity=35.1351351351351, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24646839, Length=291, Percent_Identity=31.9587628865979, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48442; Mature: 48442

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAHRAILASLALGASVLAASASARPNALPRPDERPSPSRRTPVVQAVEKVRGAVVNVSA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECH
EELVRIRVPSRASSMAELLFGDFFEKPRFRKGYAVSSLGSGVIVSPDGYVLTNNHVVERG
HHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCCEEEECCHHHHCC
ARFRVGLLDGREINAKVVGTDPSSDLAVLKLETKERLPFATLGRSDDLLIGETLIAIGNP
CEEEEEEECCCEECEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCEEECCEEEEECCC
FGLSHTVTTGVVSAVHRNFRAGDRMLFDFVQTDASINPGNSGGALLDIEGRLVGINTAIL
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEE
GDRNAGIGFAIPIDRARRIAEDLIAHGEVREGYVGVAVDDLPAKDGAAEGASGGVVVTGV
CCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEC
DPGSPAAKAGVKKGDVVEAVQGFAARSAEEFRFRMRDLPIGQAARLELVRGGKRIALSVP
CCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECC
SVELSPEAAAQLATRSTGLTLAEERLHRGSVLIVKTVAPASPAARVGIRQGDLVREVNST
CEEECHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCHHHHCCCC
EVATLADFRRAAARARRSGQLVLLVQRGYAAERIAFDFQ
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MRAHRAILASLALGASVLAASASARPNALPRPDERPSPSRRTPVVQAVEKVRGAVVNVSA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECH
EELVRIRVPSRASSMAELLFGDFFEKPRFRKGYAVSSLGSGVIVSPDGYVLTNNHVVERG
HHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCCEEEECCHHHHCC
ARFRVGLLDGREINAKVVGTDPSSDLAVLKLETKERLPFATLGRSDDLLIGETLIAIGNP
CEEEEEEECCCEECEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCEEECCEEEEECCC
FGLSHTVTTGVVSAVHRNFRAGDRMLFDFVQTDASINPGNSGGALLDIEGRLVGINTAIL
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEE
GDRNAGIGFAIPIDRARRIAEDLIAHGEVREGYVGVAVDDLPAKDGAAEGASGGVVVTGV
CCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEC
DPGSPAAKAGVKKGDVVEAVQGFAARSAEEFRFRMRDLPIGQAARLELVRGGKRIALSVP
CCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECC
SVELSPEAAAQLATRSTGLTLAEERLHRGSVLIVKTVAPASPAARVGIRQGDLVREVNST
CEEECHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCHHHHCCCC
EVATLADFRRAAARARRSGQLVLLVQRGYAAERIAFDFQ
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]