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The map label for this gene is paaK [H]

Identifier: 153002918

GI number: 153002918

Start: 52652

End: 53977

Strand: Reverse

Name: paaK [H]

Synonym: Anae109_0039

Alternate gene names: 153002918

Gene position: 53977-52652 (Counterclockwise)

Preceding gene: 153002919

Following gene: 153002914

Centisome position: 1.02

GC content: 74.06

Gene sequence:

>1326_bases
GTGTCCACGCCCCTGCTCGAGAGCGCGATCTTCGATCCCGCCGAGACCCTGCCCGTCCCCGAGCGGCGCGCGCTGCAGGC
GCGCCGCCTCGCCGAGACCGTCCGCCGCGCGGCGGCGGTGCCGTTCTACCGCGACGCGCTCGGGCGCGCCGGCGCCGGCG
CGGACGCGATCCGCTCGGCGGACGACGTCCGGCGCCTCCCCTTCACGACGAAGGACGATCTCCGCCAGAGCTATCCGCTC
GGCCTGCTCGCCGTCCCTCGCGCCGAGCTGGCCCGGGTGCACGGCTCGTCCGGCACGACGGGCAAGCCCACCTTCGTCGC
GTACACGCGGGCCGACCTCGACACCTGGTCCGGCCTGGTGGCGCGCTTCCTGGTGGCCGGCGGGCTGCGCCCCGAGCACC
TCGTCCACGTCGCCTTCGGCTACGGGCTCTTCACCGGCGGCTTCGGCCTGCACTACGGCATCGAGCGGGTCGGCGCCGCG
GTGGTCCCCGCCGCCGGCGGGAACACGCCGCGCCAGGTGATGCTCATCCGCGACCTCGGCGCGGAGGTGCTCGTCTGCAC
CCCCTCGTACGCGCTGCACATCGCGGAGGTGGCGCGCGCGGAGGGCTACCGGCCGGGCGAGCTGCCGCTCAGGTTCGGCC
ACTTCGGCGGCGAGCCCTGGACGGAGGAGATGCGCATCACCCTCGAGCGCGAGCTCGGCATCCTGGCCTTCAACAACTAC
GGCCTCTCCGAGGTGGTCGGCCCGGGGGTCGCCGGCGAGTGCTCCCACCGCACCGGCATGCACGTGCAGGAGGACCACTT
CCTCGTGGAGTGCGTGGATCCCGACACCCTCGCGCACGTCCCGGACGGCGAGGTGGGCGAGCTGGTGTTCACGACCCTCA
CCAAGCAGGCGATGCCGGTGCTCCGCTACCGCACCCGCGATCTCGCGGCGCTCGACCGCTCCCCGTGCCCGTGCGGGCGC
ACCGGCGTGCGCATGAGCCGGGTGGTCGGCCGCTCCGACGACATGCTCATCATCCGCGGCGTGAACGTCTTCCCGTCGCA
GGTCGAGGAGGCGCTGCTGCGCGTCGAGGGGACCGCGCCGCACTACCTCATCGAGGTCTCGCGCCCCGGCTCGCTCGACG
AGGCGGTGGTGAAGGTGGAGATGCGCCCCGCGGACTTCCGCGACGAGATGCGGCAGCTCCAGGAGCTGCACGACCGCATC
GACCGGGAGATCCACGCCGTCACCGGCGTGCGCATGACGGTGGAGCTCGTCGCGCCCAACACCCTCGAGCGCTCCGCCGG
CAAGGCGCAGCGCGTGCTCGATCACCGGCGGACCGGCCGCGCCTGA

Upstream 100 bases:

>100_bases
GAGGACCCCGACCGCGCCGCGAAGCTCCTCGAGGCGGCGGGCGTGAAGCTCGTCCCCTCCGACGAGCTCTTCGCCCGCTC
GGGCGCGTAGGGGAGCGACC

Downstream 100 bases:

>100_bases
GGTCGCGGCGTCCGCCGCGCCGGCTAGGGCGCCCCGGCGGGCGCCCGCGCCGGCGCGAGGGCCCTCGCCGCGACCGGGAG
GCTCTCCCCGAAGCGCGTCA

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSTPLLESAIFDPAETLPVPERRALQARRLAETVRRAAAVPFYRDALGRAGAGADAIRSADDVRRLPFTTKDDLRQSYPL
GLLAVPRAELARVHGSSGTTGKPTFVAYTRADLDTWSGLVARFLVAGGLRPEHLVHVAFGYGLFTGGFGLHYGIERVGAA
VVPAAGGNTPRQVMLIRDLGAEVLVCTPSYALHIAEVARAEGYRPGELPLRFGHFGGEPWTEEMRITLERELGILAFNNY
GLSEVVGPGVAGECSHRTGMHVQEDHFLVECVDPDTLAHVPDGEVGELVFTTLTKQAMPVLRYRTRDLAALDRSPCPCGR
TGVRMSRVVGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGSLDEAVVKVEMRPADFRDEMRQLQELHDRI
DREIHAVTGVRMTVELVAPNTLERSAGKAQRVLDHRRTGRA

Sequences:

>Translated_441_residues
MSTPLLESAIFDPAETLPVPERRALQARRLAETVRRAAAVPFYRDALGRAGAGADAIRSADDVRRLPFTTKDDLRQSYPL
GLLAVPRAELARVHGSSGTTGKPTFVAYTRADLDTWSGLVARFLVAGGLRPEHLVHVAFGYGLFTGGFGLHYGIERVGAA
VVPAAGGNTPRQVMLIRDLGAEVLVCTPSYALHIAEVARAEGYRPGELPLRFGHFGGEPWTEEMRITLERELGILAFNNY
GLSEVVGPGVAGECSHRTGMHVQEDHFLVECVDPDTLAHVPDGEVGELVFTTLTKQAMPVLRYRTRDLAALDRSPCPCGR
TGVRMSRVVGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGSLDEAVVKVEMRPADFRDEMRQLQELHDRI
DREIHAVTGVRMTVELVAPNTLERSAGKAQRVLDHRRTGRA
>Mature_440_residues
STPLLESAIFDPAETLPVPERRALQARRLAETVRRAAAVPFYRDALGRAGAGADAIRSADDVRRLPFTTKDDLRQSYPLG
LLAVPRAELARVHGSSGTTGKPTFVAYTRADLDTWSGLVARFLVAGGLRPEHLVHVAFGYGLFTGGFGLHYGIERVGAAV
VPAAGGNTPRQVMLIRDLGAEVLVCTPSYALHIAEVARAEGYRPGELPLRFGHFGGEPWTEEMRITLERELGILAFNNYG
LSEVVGPGVAGECSHRTGMHVQEDHFLVECVDPDTLAHVPDGEVGELVFTTLTKQAMPVLRYRTRDLAALDRSPCPCGRT
GVRMSRVVGRSDDMLIIRGVNVFPSQVEEALLRVEGTAPHYLIEVSRPGSLDEAVVKVEMRPADFRDEMRQLQELHDRID
REIHAVTGVRMTVELVAPNTLERSAGKAQRVLDHRRTGRA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=437, Percent_Identity=48.7414187643021, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48286; Mature: 48155

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLLESAIFDPAETLPVPERRALQARRLAETVRRAAAVPFYRDALGRAGAGADAIRSA
CCCCHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHCH
DDVRRLPFTTKDDLRQSYPLGLLAVPRAELARVHGSSGTTGKPTFVAYTRADLDTWSGLV
HHHHHCCCCCHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHH
ARFLVAGGLRPEHLVHVAFGYGLFTGGFGLHYGIERVGAAVVPAAGGNTPRQVMLIRDLG
HHHHHHCCCCHHHEEEEEEHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCEEEEEEECC
AEVLVCTPSYALHIAEVARAEGYRPGELPLRFGHFGGEPWTEEMRITLERELGILAFNNY
CEEEEECCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHEEEECCCCEEEECCC
GLSEVVGPGVAGECSHRTGMHVQEDHFLVECVDPDTLAHVPDGEVGELVFTTLTKQAMPV
CHHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRYRTRDLAALDRSPCPCGRTGVRMSRVVGRSDDMLIIRGVNVFPSQVEEALLRVEGTAP
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCC
HYLIEVSRPGSLDEAVVKVEMRPADFRDEMRQLQELHDRIDREIHAVTGVRMTVELVAPN
EEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
TLERSAGKAQRVLDHRRTGRA
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STPLLESAIFDPAETLPVPERRALQARRLAETVRRAAAVPFYRDALGRAGAGADAIRSA
CCCHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHCH
DDVRRLPFTTKDDLRQSYPLGLLAVPRAELARVHGSSGTTGKPTFVAYTRADLDTWSGLV
HHHHHCCCCCHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHH
ARFLVAGGLRPEHLVHVAFGYGLFTGGFGLHYGIERVGAAVVPAAGGNTPRQVMLIRDLG
HHHHHHCCCCHHHEEEEEEHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCEEEEEEECC
AEVLVCTPSYALHIAEVARAEGYRPGELPLRFGHFGGEPWTEEMRITLERELGILAFNNY
CEEEEECCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHEEEECCCCEEEECCC
GLSEVVGPGVAGECSHRTGMHVQEDHFLVECVDPDTLAHVPDGEVGELVFTTLTKQAMPV
CHHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRYRTRDLAALDRSPCPCGRTGVRMSRVVGRSDDMLIIRGVNVFPSQVEEALLRVEGTAP
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCC
HYLIEVSRPGSLDEAVVKVEMRPADFRDEMRQLQELHDRIDREIHAVTGVRMTVELVAPN
EEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
TLERSAGKAQRVLDHRRTGRA
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]