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The map label for this gene is engD [H]

Identifier: 152977674

GI number: 152977674

Start: 4074346

End: 4075446

Strand: Reverse

Name: engD [H]

Synonym: Bcer98_4015

Alternate gene names: 152977674

Gene position: 4075446-4074346 (Counterclockwise)

Preceding gene: 152977675

Following gene: 152977673

Centisome position: 99.72

GC content: 36.78

Gene sequence:

>1101_bases
ATGGGATTAACGGCTGGAATCGTTGGCTTACCTAACGTAGGGAAATCAACATTATTTAACGCAATTACACAAGCAGGGGC
AGAATCTGCAAACTATCCATTCTGTACAATTGATCCAAACGTAGGAATTGTAGAGGTGCCAGATGATCGTTTAAATAAAC
TAACGGAACTAGTTGAGCCGAAGAAAACTGTTCCAACGGTATTCGAATTTACTGATATTGCTGGTATTGTAAAAGGTGCA
AGTAAAGGTGAAGGATTAGGAAACAAATTCTTATCTCATATTCGCCAAGTAGATGCAATTTGCCAAGTGGTACGTTGTTT
TGAAGATGAAAATATTACACACGTTTCAGGAAAAGTCGATCCAATTGATGATATTGAAACGATTAACCTAGAATTAATTT
TAGCGGATTTAGAATCTGTTGATAAGCGTATTGAACGTGTTGCTAAATTAGCAAGACAAAAAGATAAAGAAGCGGTATTT
GAGCATGAAATTTTAGTTCGTTTAAAAGAAGCGTTTGAAGCAGGGAAACCAGCTCGTACGATCGAGTTTACAGAAGAACA
AATGAAGGTTGTTAAAGGGCTTCATTTACTTACAACGAAAGAAATGCTATACGTAGCAAACGTAAGTGAAGAGGATATTA
TGGATCCTTCTGAGAACCAGTATGTACAGAGGGTAAAAGAATTTGCAGCAAAAGAAAATTCACAAGTTATTGTTGTTTGT
GCAAAAATTGAATCAGAAATTGCTGAATTAGATGAAGAAGAGAAAAAGGTATTCCTTGAAGAATTAGGCATTGAAGAGTC
TGGTTTAGATCAATTAATTCGTGCCGCGTATGATTTGTTAGGACTAGCAACTTACTTTACAGCTGGTGTACAAGAAGTTC
GCGCATGGACATTTAAAAAAGGGATGAAAGCACCACAATGCGCAGGAGTGATTCATACAGATTTCGAACGTGGATTTATT
CGCGCTGAAACAGTTTCATATACTGATTTAATGGAATATGGTTCGATGACAGCGGCGAAAGAAGCAGGAAAAGTACGTTT
AGAAGGTAAAGAGTATATTGTAAAAGACGGGGACATTATGCACTTCCGCTTTAATGTATAA

Upstream 100 bases:

>100_bases
TACATAAGGTAGCTGTTACTTTTTTGAATTTTTAGGTAACTTGTCATTTTATTTGTTACTATCTATAATGATGGAAGATT
GAGACATAGGAGTGAAAAAT

Downstream 100 bases:

>100_bases
TTTGATATTTCCTAGGAAAATAGTGAGAAAAGCTTGGTGAATATATTATATGTTTACCAAGTTTTTTATTTATTGGTTAG
TTGATTCATCTAACTTACTA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLNKLTELVEPKKTVPTVFEFTDIAGIVKGA
SKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVF
EHEILVRLKEAFEAGKPARTIEFTEEQMKVVKGLHLLTTKEMLYVANVSEEDIMDPSENQYVQRVKEFAAKENSQVIVVC
AKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKKGMKAPQCAGVIHTDFERGFI
RAETVSYTDLMEYGSMTAAKEAGKVRLEGKEYIVKDGDIMHFRFNV

Sequences:

>Translated_366_residues
MGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLNKLTELVEPKKTVPTVFEFTDIAGIVKGA
SKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVF
EHEILVRLKEAFEAGKPARTIEFTEEQMKVVKGLHLLTTKEMLYVANVSEEDIMDPSENQYVQRVKEFAAKENSQVIVVC
AKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKKGMKAPQCAGVIHTDFERGFI
RAETVSYTDLMEYGSMTAAKEAGKVRLEGKEYIVKDGDIMHFRFNV
>Mature_365_residues
GLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLNKLTELVEPKKTVPTVFEFTDIAGIVKGAS
KGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVFE
HEILVRLKEAFEAGKPARTIEFTEEQMKVVKGLHLLTTKEMLYVANVSEEDIMDPSENQYVQRVKEFAAKENSQVIVVCA
KIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKKGMKAPQCAGVIHTDFERGFIR
AETVSYTDLMEYGSMTAAKEAGKVRLEGKEYIVKDGDIMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=45.2574525745258, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI58761502, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI24308117, Length=111, Percent_Identity=37.8378378378378, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=57.103825136612, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1789574, Length=134, Percent_Identity=31.3432835820896, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.0765027322404, Blast_Score=313, Evalue=8e-86,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=42.2043010752688, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6321773, Length=385, Percent_Identity=37.6623376623377, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6321649, Length=226, Percent_Identity=30.9734513274336, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321962, Length=147, Percent_Identity=27.2108843537415, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640873, Length=370, Percent_Identity=42.4324324324324, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24640877, Length=370, Percent_Identity=42.4324324324324, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24640875, Length=370, Percent_Identity=42.4324324324324, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=40.1215805471125, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24585318, Length=164, Percent_Identity=31.0975609756098, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40757; Mature: 40626

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLNKLTELVEP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTVFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVD
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVFEHEILVRLKEAFEAGKPART
CCCCCHHEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEFTEEQMKVVKGLHLLTTKEMLYVANVSEEDIMDPSENQYVQRVKEFAAKENSQVIVVC
HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEE
AKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKK
HHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMKAPQCAGVIHTDFERGFIRAETVSYTDLMEYGSMTAAKEAGKVRLEGKEYIVKDGDIM
CCCCCCCCCCEECHHHCCEEEEHHCCHHHHHHHCCHHHHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
GLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLNKLTELVEP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTVFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVD
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVFEHEILVRLKEAFEAGKPART
CCCCCHHEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEFTEEQMKVVKGLHLLTTKEMLYVANVSEEDIMDPSENQYVQRVKEFAAKENSQVIVVC
HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEE
AKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKK
HHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMKAPQCAGVIHTDFERGFIRAETVSYTDLMEYGSMTAAKEAGKVRLEGKEYIVKDGDIM
CCCCCCCCCCEECHHHCCEEEEHHCCHHHHHHHCCHHHHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]