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The map label for this gene is yycG [H]

Identifier: 152977664

GI number: 152977664

Start: 4063074

End: 4064933

Strand: Reverse

Name: yycG [H]

Synonym: Bcer98_4005

Alternate gene names: 152977664

Gene position: 4064933-4063074 (Counterclockwise)

Preceding gene: 152977665

Following gene: 152977663

Centisome position: 99.46

GC content: 36.13

Gene sequence:

>1860_bases
ATGAAGAAAGTTGGTTTTTTTCAATCTATTCATTTTAAGTTTGTGCTCATCTATATGCTATTAATATTAATAGCAATGCA
GGTTATCGGTGTATATTTTGTACGTGAGCTAGAAAAGAGCCTCGTGCAAAGTTTTAAAGACTCATTAACACAACAAACGA
ACTTATTGTCTTATAACTTAAAGCAGGAATTTAATAAAGAATTTAATAAAGAACGTGATAAAAACGAGATATCTTTCCAG
CAGGCTGTTAATAACTCGATTGAGAAGTTTGCGAATGACCGAAAGCGTGATATTCAGGAAGTAAGTGTCTTTGATCGTAA
TAGGAAACTATTGGCGACTTCTGATAATTCGCCAGCTAAGAAAAGCCAGGTGAATCGAGCGTCTACCGATATAACTGTTC
AACGAGTCATTGTACAAAATAAGCCGGAATCAAAGATTGAGAAGGATGGAAGTACGGGACATCGTGTTCAAGTTATGTTT
ACCCCAATTGAAAGGAATCAAGGGGAAGAGGAAGTAGCAGGAGTTATAAAAATCGTTGCTTCTATGGAAGATGTATATAA
GCAAATGAAAGATATTAATCAAATTTTTGCAACAGGGACAGTTATTGCATTACTAGTAACTGCCGTTCTAGGTATTTTAT
TGGCTCAAACGATTACAAGACCAATTTCAGATATGAGAAGACAGGCTATTGAAATGGCGAAGGGAAATTACTCACGCAAA
GTAAAAGTACATAGCCATGATGAAATTGGACAATTGGCACTATCTTTTAACAACCTATCGAAAAAATTACAACAAGCCCG
TTCTTCAACAGAAAGTGAAAGACGCAAGCTATCATCGGTTTTATCACATATGACTGATGGTGTAATTGCTACGGATCGAA
AAGGGGATATTATTTTATTAAATGACCCTGCTGAAAAAATGCTGAATGTTTCGCGTGAAACAGCATTGGATCAATCGATT
TTAGAAATATTAGGGATTCAGGAAGAGTTTACACTAGATCATTTATATGAAGAACCTGATTCAGTTTTATTAGATTTCAG
TACACGTAATGAACCGTACATTTTAAGAGCTAGTTTTTCTGTTATTCAAAAAGATACTGGTAAAGCAAATGGCTTAATTG
CTGTATTGTATGATGTAACGGAACAAGAGCGAATTGATCGTGAACGTCGTGAGTTTGTAGCGAATGTATCACATGAGTTG
CGAACGCCACTTACAACGATGCGAAGCTATCTTGAAGCGTTAAGTGATGGAGCGTGGAAAGATCCAAATATTGCTCCGCA
ATTTTTAACAGTCACACAAGAAGAGACTGAAAGAATGATTCGACTTGTAAACGCATTGTTACAACTATCTAAAATGGATA
GTACAGAATATCGTTTAATGAAAGAATGGGTAGATTTTACGGAGTTCTTTAATAATGTCATTGATCGATTTGAAATGTCT
AAGGAACAAAATGTAATCTTCAATCGTTCTTTTTCGAAAAAAGCAAGATTTGTTGATATGGATACAGACAAAATTACCCA
AGTTTTATACAATGTTATTTCAAATGCCCTGAAATATTCACCGGAAGGCGGAACGATAACATATCGTTTACGCGATCGTG
GGGATATGTTAGAAATTAGCGTTAGCGATCAAGGTATGGGAATCCCGAAAGAAAACGTCGATAAAATTTTTGAACGCTTT
TATCGCGTAGATAAGGCGCGTTCAAGACAAATGGGAGGAACTGGTCTAGGTTTAGCAATTGCTAAAGAAATGATTATTGC
ACATGGTGGATCTATTTGGGCAAAGAGTGAAGAAGGAAAAGGAACGACAATTTACTTTACCCTCCCGTTGGCGAAAGAAG
AAGAGGACGATTGGGAATGA

Upstream 100 bases:

>100_bases
TTTACGTGAAAAGATTGAAGATAATCCAAGTCATCCAACTCTAATTGTTACGAGACGTGGAGTAGGATATTACTTGCGTG
ACCCAGAGCAGGAATAAAAC

Downstream 100 bases:

>100_bases
ATATGGAAAACTTTAAAACCATTGTGCTAATTAATTTAGTAGTTATTAGTTTGTTTCTTACGTTTAATCTATGGACATAT
GTGCCTGATTCTAATTCGAT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MKKVGFFQSIHFKFVLIYMLLILIAMQVIGVYFVRELEKSLVQSFKDSLTQQTNLLSYNLKQEFNKEFNKERDKNEISFQ
QAVNNSIEKFANDRKRDIQEVSVFDRNRKLLATSDNSPAKKSQVNRASTDITVQRVIVQNKPESKIEKDGSTGHRVQVMF
TPIERNQGEEEVAGVIKIVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRK
VKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSI
LEILGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKDTGKANGLIAVLYDVTEQERIDRERREFVANVSHEL
RTPLTTMRSYLEALSDGAWKDPNIAPQFLTVTQEETERMIRLVNALLQLSKMDSTEYRLMKEWVDFTEFFNNVIDRFEMS
KEQNVIFNRSFSKKARFVDMDTDKITQVLYNVISNALKYSPEGGTITYRLRDRGDMLEISVSDQGMGIPKENVDKIFERF
YRVDKARSRQMGGTGLGLAIAKEMIIAHGGSIWAKSEEGKGTTIYFTLPLAKEEEDDWE

Sequences:

>Translated_619_residues
MKKVGFFQSIHFKFVLIYMLLILIAMQVIGVYFVRELEKSLVQSFKDSLTQQTNLLSYNLKQEFNKEFNKERDKNEISFQ
QAVNNSIEKFANDRKRDIQEVSVFDRNRKLLATSDNSPAKKSQVNRASTDITVQRVIVQNKPESKIEKDGSTGHRVQVMF
TPIERNQGEEEVAGVIKIVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRK
VKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSI
LEILGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKDTGKANGLIAVLYDVTEQERIDRERREFVANVSHEL
RTPLTTMRSYLEALSDGAWKDPNIAPQFLTVTQEETERMIRLVNALLQLSKMDSTEYRLMKEWVDFTEFFNNVIDRFEMS
KEQNVIFNRSFSKKARFVDMDTDKITQVLYNVISNALKYSPEGGTITYRLRDRGDMLEISVSDQGMGIPKENVDKIFERF
YRVDKARSRQMGGTGLGLAIAKEMIIAHGGSIWAKSEEGKGTTIYFTLPLAKEEEDDWE
>Mature_619_residues
MKKVGFFQSIHFKFVLIYMLLILIAMQVIGVYFVRELEKSLVQSFKDSLTQQTNLLSYNLKQEFNKEFNKERDKNEISFQ
QAVNNSIEKFANDRKRDIQEVSVFDRNRKLLATSDNSPAKKSQVNRASTDITVQRVIVQNKPESKIEKDGSTGHRVQVMF
TPIERNQGEEEVAGVIKIVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRK
VKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSI
LEILGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKDTGKANGLIAVLYDVTEQERIDRERREFVANVSHEL
RTPLTTMRSYLEALSDGAWKDPNIAPQFLTVTQEETERMIRLVNALLQLSKMDSTEYRLMKEWVDFTEFFNNVIDRFEMS
KEQNVIFNRSFSKKARFVDMDTDKITQVLYNVISNALKYSPEGGTITYRLRDRGDMLEISVSDQGMGIPKENVDKIFERF
YRVDKARSRQMGGTGLGLAIAKEMIIAHGGSIWAKSEEGKGTTIYFTLPLAKEEEDDWE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=371, Percent_Identity=32.0754716981132, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI48994928, Length=309, Percent_Identity=32.0388349514563, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=33.1858407079646, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788549, Length=625, Percent_Identity=24.16, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=32.8767123287671, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=29.6943231441048, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=28.4046692607004, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=31.1965811965812, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=30.9623430962343, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=27.4774774774775, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=27.3109243697479, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=31.7796610169492, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=27.2357723577236, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=28.6885245901639, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=195, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=213, Percent_Identity=29.1079812206573, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787374, Length=214, Percent_Identity=28.9719626168224, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70869; Mature: 70869

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGFFQSIHFKFVLIYMLLILIAMQVIGVYFVRELEKSLVQSFKDSLTQQTNLLSYNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQEFNKEFNKERDKNEISFQQAVNNSIEKFANDRKRDIQEVSVFDRNRKLLATSDNSPAK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
KSQVNRASTDITVQRVIVQNKPESKIEKDGSTGHRVQVMFTPIERNQGEEEVAGVIKIVA
HHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
SMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILL
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
NDPAEKMLNVSRETALDQSILEILGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFS
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEHHH
VIQKDTGKANGLIAVLYDVTEQERIDRERREFVANVSHELRTPLTTMRSYLEALSDGAWK
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DPNIAPQFLTVTQEETERMIRLVNALLQLSKMDSTEYRLMKEWVDFTEFFNNVIDRFEMS
CCCCCCHHEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KEQNVIFNRSFSKKARFVDMDTDKITQVLYNVISNALKYSPEGGTITYRLRDRGDMLEIS
CCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEE
VSDQGMGIPKENVDKIFERFYRVDKARSRQMGGTGLGLAIAKEMIIAHGGSIWAKSEEGK
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GTTIYFTLPLAKEEEDDWE
CCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKKVGFFQSIHFKFVLIYMLLILIAMQVIGVYFVRELEKSLVQSFKDSLTQQTNLLSYNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQEFNKEFNKERDKNEISFQQAVNNSIEKFANDRKRDIQEVSVFDRNRKLLATSDNSPAK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
KSQVNRASTDITVQRVIVQNKPESKIEKDGSTGHRVQVMFTPIERNQGEEEVAGVIKIVA
HHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
SMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILL
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
NDPAEKMLNVSRETALDQSILEILGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFS
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEHHH
VIQKDTGKANGLIAVLYDVTEQERIDRERREFVANVSHELRTPLTTMRSYLEALSDGAWK
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DPNIAPQFLTVTQEETERMIRLVNALLQLSKMDSTEYRLMKEWVDFTEFFNNVIDRFEMS
CCCCCCHHEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KEQNVIFNRSFSKKARFVDMDTDKITQVLYNVISNALKYSPEGGTITYRLRDRGDMLEIS
CCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEE
VSDQGMGIPKENVDKIFERFYRVDKARSRQMGGTGLGLAIAKEMIIAHGGSIWAKSEEGK
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GTTIYFTLPLAKEEEDDWE
CCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]