Click here to switch to the map view.

The map label for this gene is tagA [H]

Identifier: 152977596

GI number: 152977596

Start: 3987554

End: 3988294

Strand: Reverse

Name: tagA [H]

Synonym: Bcer98_3934

Alternate gene names: 152977596

Gene position: 3988294-3987554 (Counterclockwise)

Preceding gene: 152977597

Following gene: 152977595

Centisome position: 97.58

GC content: 38.46

Gene sequence:

>741_bases
ATGGCAGTACAAACAGTTGATATTTTAGGTGTTCCTTTCTCTACAATGACGATGGAAGAAACTGTACAATACCTTATGAA
ACAGTTGGAAGTTGAACAAGCTCATACATTTCAAGTTGTAACAGCAAATCCTGAAATTGTCATGTGCGCAAAAAAAGATT
CAAGTTTCCAAAAAACACTTTTACAAGCAGATGTAATTACACCAGATGGCATTGGTGTTGTAAAAGCAAGCGCTATGTTA
GGGACACCGCTTCAAGAACGAGTAGCAGGCTTTGATTTAATGAATCATTTATTTGGAGAACTTTCAAAAGAAAAGAAATC
TGTATCCGTGTTCTTGTTAGGTGCAAAGCCGCATGTTGTGAAAGGCGCTGCCGATTACTTAAAGAAAACATATTCGGCTA
TAAACATTGTTGGTTTGCAGGATGGCTACTTTAAGCCTGAAGAAGAAGAGAATATTATTTCGCGTATTCAAGAAGCAAAA
CCAGATCTACTACTTGTTGCACTTGGATTCCCAAGACAAGAAAATTTCATTCAAAATAATAAAAATCGATTACAAGCAAA
GATGGCAGTCGGTGTAGGTGGAAGTTTTGATGTTTGGGCTGGTGAGGTAAAGCGCGCACCAAAATGGATCCAAGCCATTC
ACTTAGAGTGGTTCTATCGTTTATGTAGTAATCCAACTCGTTGGCGCCGTCAGCTTGTATTGGCAGAGTTTTTAAAGGAA
GTAATGCGTTCGAAGAAGTAG

Upstream 100 bases:

>100_bases
TGCAGCAAATTTCTCACTGAACAAGTTATATGAGGATACGAAAGAAACATATAAACAATTAATAGCGAAATAACCTTGAA
TAATAGAGAGGATTGTAATT

Downstream 100 bases:

>100_bases
CGAGGTCTCGCTGCTTTTTTTTATACATATGAACACGGTAGAGTCGACTACCATCCATTTATGACGTAAGTAATGAAAGG
ATAAATCTAAGGGAATGATA

Product: WecB/TagA/CpsF family glycosyl transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAVQTVDILGVPFSTMTMEETVQYLMKQLEVEQAHTFQVVTANPEIVMCAKKDSSFQKTLLQADVITPDGIGVVKASAML
GTPLQERVAGFDLMNHLFGELSKEKKSVSVFLLGAKPHVVKGAADYLKKTYSAINIVGLQDGYFKPEEEENIISRIQEAK
PDLLLVALGFPRQENFIQNNKNRLQAKMAVGVGGSFDVWAGEVKRAPKWIQAIHLEWFYRLCSNPTRWRRQLVLAEFLKE
VMRSKK

Sequences:

>Translated_246_residues
MAVQTVDILGVPFSTMTMEETVQYLMKQLEVEQAHTFQVVTANPEIVMCAKKDSSFQKTLLQADVITPDGIGVVKASAML
GTPLQERVAGFDLMNHLFGELSKEKKSVSVFLLGAKPHVVKGAADYLKKTYSAINIVGLQDGYFKPEEEENIISRIQEAK
PDLLLVALGFPRQENFIQNNKNRLQAKMAVGVGGSFDVWAGEVKRAPKWIQAIHLEWFYRLCSNPTRWRRQLVLAEFLKE
VMRSKK
>Mature_245_residues
AVQTVDILGVPFSTMTMEETVQYLMKQLEVEQAHTFQVVTANPEIVMCAKKDSSFQKTLLQADVITPDGIGVVKASAMLG
TPLQERVAGFDLMNHLFGELSKEKKSVSVFLLGAKPHVVKGAADYLKKTYSAINIVGLQDGYFKPEEEENIISRIQEAKP
DLLLVALGFPRQENFIQNNKNRLQAKMAVGVGGSFDVWAGEVKRAPKWIQAIHLEWFYRLCSNPTRWRRQLVLAEFLKEV
MRSKK

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=211, Percent_Identity=35.0710900473934, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 27702; Mature: 27570

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQTVDILGVPFSTMTMEETVQYLMKQLEVEQAHTFQVVTANPEIVMCAKKDSSFQKTL
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHHHHH
LQADVITPDGIGVVKASAMLGTPLQERVAGFDLMNHLFGELSKEKKSVSVFLLGAKPHVV
HHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEE
KGAADYLKKTYSAINIVGLQDGYFKPEEEENIISRIQEAKPDLLLVALGFPRQENFIQNN
HHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCC
KNRLQAKMAVGVGGSFDVWAGEVKRAPKWIQAIHLEWFYRLCSNPTRWRRQLVLAEFLKE
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VMRSKK
HHHHCC
>Mature Secondary Structure 
AVQTVDILGVPFSTMTMEETVQYLMKQLEVEQAHTFQVVTANPEIVMCAKKDSSFQKTL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHHHHH
LQADVITPDGIGVVKASAMLGTPLQERVAGFDLMNHLFGELSKEKKSVSVFLLGAKPHVV
HHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEE
KGAADYLKKTYSAINIVGLQDGYFKPEEEENIISRIQEAKPDLLLVALGFPRQENFIQNN
HHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCC
KNRLQAKMAVGVGGSFDVWAGEVKRAPKWIQAIHLEWFYRLCSNPTRWRRQLVLAEFLKE
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VMRSKK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]