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The map label for this gene is pyrG [H]

Identifier: 152977524

GI number: 152977524

Start: 3916894

End: 3918501

Strand: Reverse

Name: pyrG [H]

Synonym: Bcer98_3859

Alternate gene names: 152977524

Gene position: 3918501-3916894 (Counterclockwise)

Preceding gene: 152977525

Following gene: 152977522

Centisome position: 95.88

GC content: 38.31

Gene sequence:

>1608_bases
ATGACTAAGTATATTTTTGTAACAGGCGGTGTAGTATCGTCTTTAGGTAAAGGGATTACAGCAGCATCTCTTGGAAGACT
TTTAAAAAATCGTGGTTTAAATGTAACCATCCAAAAATTTGACCCATACATTAACGTAGACCCAGGGACAATGAGTCCAT
ATCAACATGGTGAGGTATTCGTAACAGATGATGGTGCGGAAACAGACTTAGACCTTGGTCACTACGAGCGTTTTATCGAT
ATTAATTTAAATAAATACAGCAACGTAACAACTGGTAAAATTTATTCTTCGGTTCTTCAAAAAGAGCGTCGTGGTGAATA
TTTAGGAGGAACAGTACAAGTTATTCCTCATATTACAAACGAAATTAAAGAGCGTGTATTCCGTGCTGGTCGCGAAACAA
ATGCGGATGTTGTTATTACAGAAATTGGTGGAACTGTTGGTGATATCGAGTCTCTACCATTCCTAGAAGCAATTCGCCAA
ATTAAGAGCGACATTGGTCGCGATAACGTAATGTATATTCACTGTACATTAATTCCGTACTTAAAAGCAGCGGGTGAAAT
GAAAACAAAGCCAACGCAACATAGCGTTAAAGAACTTCGTAGCTTAGGTATTCAGCCAAATATTATCGTTGTTCGTACAG
AAATGCCTGTTTCTCAAGATATGAAAGATAAACTTGCATTATTCTGTGATATTGATCCAAAAGCAGTTATTGAAGCTGCA
GATGCAGACACATTATATGCAGTTCCATTATCTCTTCAAGAGCAAAATATGGACCAAATCGTTTGCGATCATTTAAAACT
AGACAACGCTCCAGCAGATATGACAGAGTGGAAAGCATTAGTTGATAAAGTACGTAACCTGTCTAAGAAAACAAGAATTG
CTCTTGTTGGTAAATATGTAGAGCTTCAAGATGCATACATTTCTGTTGTAGAAGCACTTCGCCATGCAGGATACACATTT
GATACAGATGTAGAAGTAAAATGGGTAAATGCTGAGCATGTAACAGCAGAAAATGTAAAAGAATTAGTTGGCGACACAGA
TGGAATCCTTGTACCTGGTGGCTTTGGTGACCGCGGTGTAGAAGGAAAAATCGTTGCAATCCAATATGCACGTGAAAATA
AAGTTCCATTCTTAGGAATTTGCTTAGGTATGCAACTTGCATCAATCGAATTTGCACGTAACGTATTAGGATTAGAAGGA
GCGAATTCTTCTGAAATCAATCCTGACACGCCTTACGCAATTATCGACTTATTACCAGAACAAAAAGATGTAGAAGACTT
AGGTGGTACACTTCGTCTTGGTTTATATCCATGTAAGCTGACTCCAGAAACAAATGCTTACAGAGCTTATAACGAGCCAG
TTGTATATGAACGTCACCGTCATCGTTATGAATTCAATAATCAATTCCGTCAAGAGATGGAAAACGCTGGATTTATCTTC
TCTGGTACAAGTCCAGATGGCCGTCTAGTAGAAATCGTTGAATTACAAGATCATCCATGGTTTGTGGCTGCACAGTTCCA
CCCAGAACTTGTATCTCGTCCAAATCGTCCACAACCATTGTTCCGTGATTTCGTACAAGCTTCTATTACAAATAAAGAAA
GCAAGTAA

Upstream 100 bases:

>100_bases
AATAAAAAGAGTCTAACAATAAGATAGATACATTGTTATCTACATACGTTGCGCTTTGCAACGGTGATTATATAACAAGA
AAGCAGAAGGGAGTACTTTC

Downstream 100 bases:

>100_bases
GAAAAAAGGGCTCGTTCCAAATGTATACTTTTGGACGAGCTCTTTTTCGATTCTTCGTATTGGTTTGTCAGTTAGCCGAC
ATGTATCATGTATATTCTTC

Product: CTP synthetase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFID
INLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITNEIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQ
IKSDIGRDNVMYIHCTLIPYLKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDPKAVIEAA
DADTLYAVPLSLQEQNMDQIVCDHLKLDNAPADMTEWKALVDKVRNLSKKTRIALVGKYVELQDAYISVVEALRHAGYTF
DTDVEVKWVNAEHVTAENVKELVGDTDGILVPGGFGDRGVEGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEG
ANSSEINPDTPYAIIDLLPEQKDVEDLGGTLRLGLYPCKLTPETNAYRAYNEPVVYERHRHRYEFNNQFRQEMENAGFIF
SGTSPDGRLVEIVELQDHPWFVAAQFHPELVSRPNRPQPLFRDFVQASITNKESK

Sequences:

>Translated_535_residues
MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFID
INLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITNEIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQ
IKSDIGRDNVMYIHCTLIPYLKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDPKAVIEAA
DADTLYAVPLSLQEQNMDQIVCDHLKLDNAPADMTEWKALVDKVRNLSKKTRIALVGKYVELQDAYISVVEALRHAGYTF
DTDVEVKWVNAEHVTAENVKELVGDTDGILVPGGFGDRGVEGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEG
ANSSEINPDTPYAIIDLLPEQKDVEDLGGTLRLGLYPCKLTPETNAYRAYNEPVVYERHRHRYEFNNQFRQEMENAGFIF
SGTSPDGRLVEIVELQDHPWFVAAQFHPELVSRPNRPQPLFRDFVQASITNKESK
>Mature_534_residues
TKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDI
NLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITNEIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQI
KSDIGRDNVMYIHCTLIPYLKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDPKAVIEAAD
ADTLYAVPLSLQEQNMDQIVCDHLKLDNAPADMTEWKALVDKVRNLSKKTRIALVGKYVELQDAYISVVEALRHAGYTFD
TDVEVKWVNAEHVTAENVKELVGDTDGILVPGGFGDRGVEGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEGA
NSSEINPDTPYAIIDLLPEQKDVEDLGGTLRLGLYPCKLTPETNAYRAYNEPVVYERHRHRYEFNNQFRQEMENAGFIFS
GTSPDGRLVEIVELQDHPWFVAAQFHPELVSRPNRPQPLFRDFVQASITNKESK

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI28559085, Length=550, Percent_Identity=45.6363636363636, Blast_Score=501, Evalue=1e-142,
Organism=Homo sapiens, GI28559083, Length=550, Percent_Identity=45.6363636363636, Blast_Score=501, Evalue=1e-142,
Organism=Homo sapiens, GI221316689, Length=550, Percent_Identity=45.6363636363636, Blast_Score=501, Evalue=1e-142,
Organism=Homo sapiens, GI148491070, Length=548, Percent_Identity=46.3503649635037, Blast_Score=500, Evalue=1e-141,
Organism=Escherichia coli, GI1789142, Length=537, Percent_Identity=55.4934823091248, Blast_Score=597, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI25148299, Length=601, Percent_Identity=40.5990016638935, Blast_Score=433, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322563, Length=560, Percent_Identity=44.8214285714286, Blast_Score=483, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6319432, Length=558, Percent_Identity=44.4444444444444, Blast_Score=483, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24664469, Length=548, Percent_Identity=47.0802919708029, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI21357815, Length=493, Percent_Identity=45.0304259634888, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 59762; Mature: 59631

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVF
CCEEEEEECHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCCCCCEEE
VTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITN
EECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
EIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDIGRDNVMYIHCTLIPY
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHH
LKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDPKAVIEAA
HHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHEEEC
DADTLYAVPLSLQEQNMDQIVCDHLKLDNAPADMTEWKALVDKVRNLSKKTRIALVGKYV
CCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEHHH
ELQDAYISVVEALRHAGYTFDTDVEVKWVNAEHVTAENVKELVGDTDGILVPGGFGDRGV
HHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCC
EGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEGANSSEINPDTPYAIIDLLPE
CCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC
QKDVEDLGGTLRLGLYPCKLTPETNAYRAYNEPVVYERHRHRYEFNNQFRQEMENAGFIF
CCCHHHCCCEEEEEEEEEEECCCCCCEECCCCCEEEHHHHHHCHHHHHHHHHHHHCCEEE
SGTSPDGRLVEIVELQDHPWFVAAQFHPELVSRPNRPQPLFRDFVQASITNKESK
ECCCCCCCEEEEEEECCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVF
CEEEEEECHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCCCCCEEE
VTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITN
EECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
EIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDIGRDNVMYIHCTLIPY
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHH
LKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDPKAVIEAA
HHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHEEEC
DADTLYAVPLSLQEQNMDQIVCDHLKLDNAPADMTEWKALVDKVRNLSKKTRIALVGKYV
CCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEHHH
ELQDAYISVVEALRHAGYTFDTDVEVKWVNAEHVTAENVKELVGDTDGILVPGGFGDRGV
HHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCC
EGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEGANSSEINPDTPYAIIDLLPE
CCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC
QKDVEDLGGTLRLGLYPCKLTPETNAYRAYNEPVVYERHRHRYEFNNQFRQEMENAGFIF
CCCHHHCCCEEEEEEEEEEECCCCCCEECCCCCEEEHHHHHHCHHHHHHHHHHHHCCEEE
SGTSPDGRLVEIVELQDHPWFVAAQFHPELVSRPNRPQPLFRDFVQASITNKESK
ECCCCCCCEEEEEEECCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA