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The map label for this gene is atpA [H]

Identifier: 152977494

GI number: 152977494

Start: 3890779

End: 3892287

Strand: Reverse

Name: atpA [H]

Synonym: Bcer98_3827

Alternate gene names: 152977494

Gene position: 3892287-3890779 (Counterclockwise)

Preceding gene: 152977495

Following gene: 152977493

Centisome position: 95.24

GC content: 41.82

Gene sequence:

>1509_bases
ATGAGCATCAGAGCTGAAGAAATTAGCGCACTGATAAAGCAACAAATTGAAAACTATCAGTCTGAAATCGAAGTTAGCGA
TGTTGGTACAGTTATCCAAGTTGGTGACGGTATCGCGCGTGCTCATGGTCTTGATAACGTTATGGCTGGTGAACTTGTAG
AGTTCGCTAACGGCGTTATGGGACTAGCACAAAACTTAGAGGAAAACAACGTAGGTATTATTATTCTAGGACCTTACACA
GAAATTCGTGAAGGTGACGAAGTTCGTCGTACAGGCCGTATTATGCAAGTGCCAGTAGGTGAAGAACTAATCGGTCGTGT
TGTGAACCCATTAGGTCAACCGGTAGACGGTTTAGGTCCAATCCATACAACAAAAACTCGTCCAATTGAAAGCCCAGCAC
CAGGTGTAATGGATCGTAAATCTGTTCATGAGCCACTTCAAACTGGTATTAAGGCAATTGATGCACTTGTGCCAATCGGT
CGTGGTCAACGTGAGCTAATCATCGGTGACCGCCAAACTGGTAAAACAGCAGTAGCACTGGATACAATCTTAAACCAAAA
AGACGAAGACATGATTTGTATCTATGTTGCAATTGGACAAAAAGAATCTACAGTACGTAACGTAGTAGAAACACTGCGTA
AGCATGGTGCATTAGAGTATACAATTGTTGTAACAGCATCAGCTTCTCAACCAGCTCCATTGTTATATTTAGCTCCTTAT
GCAGGTGTATCAATGGGTGAAGAATTCATGTACAACGGAAAACACGTATTAGTCGTGTATGATGACTTATCAAAACAAGC
AGCTGCTTACCGTGAGCTATCATTACTATTACGTCGTCCTCCAGGTCGTGAAGCATATCCAGGGGATGTATTCTACTTAC
ATTCTCGCTTACTAGAGCGTGCAGCAAAATTAAGCGATGCAAAAGGCGGTGGCTCATTAACAGCTCTACCTTTCATCGAA
ACACAAGCAGGGGACGTATCAGCATACATCCCAACAAACGTAATCTCCATTACAGATGGACAAATCTTCTTGCAATCTGA
CTTGTTCTTCTCTGGCGTACGTCCAGCAATCGATGCAGGTACTTCAGTATCTCGTGTTGGTGGATCTGCTCAGATTAAAG
CGATGAGTAAAGTATCAGGTACACTTCGTCTTGACCTTGCATCTTACCGTGAGTTAGAAGCGTTTGCTCAGTTCGGTTCT
GACCTTGATAAAGCAACACAAGCGAAACTAAATCGCGGTGCTCGCACAGTTGAAGTATTAAAACAAGGATTACACAAACC
ATTGCGAGTAGAGAAACAAGTTATGATTCTTTACGCTTTAACACGTGGATTCCTAGATGATATTCCAGTAGCAGATATCA
CTCGCTTTGAAGAAGAATTCTATGCTTGGTTAGATTCAAATGCAGCTGATTTATTAGAAGAAATCCGTACAACGAAGAAA
CTTGCGGATGACGACAAATTTGCAGCAGCAATCAATGGATTTAAAAAAGTATTCGTAGCTTCTGAATAA

Upstream 100 bases:

>100_bases
TTAAAGTGCGCATTGGAAATCGCATTTACGATGGAAGTTTACAAGGAAAATTAGCACGTATTCAGCGTGAACTAATGAAG
AATAGATAGGGGTGAAGCAC

Downstream 100 bases:

>100_bases
TAAAAAAAGCGGAGGTGGCTCGTCCAGAAGGGGAGGACATTGGACCTCCTGACGAAGAGGCGTTTTGGCCTCGCAGGAAA
TGGGAAATGATTGCCCCTTC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFANGVMGLAQNLEENNVGIIILGPYT
EIREGDEVRRTGRIMQVPVGEELIGRVVNPLGQPVDGLGPIHTTKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTAVALDTILNQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
AGVSMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIE
TQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVMILYALTRGFLDDIPVADITRFEEEFYAWLDSNAADLLEEIRTTKK
LADDDKFAAAINGFKKVFVASE

Sequences:

>Translated_502_residues
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFANGVMGLAQNLEENNVGIIILGPYT
EIREGDEVRRTGRIMQVPVGEELIGRVVNPLGQPVDGLGPIHTTKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTAVALDTILNQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
AGVSMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIE
TQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVMILYALTRGFLDDIPVADITRFEEEFYAWLDSNAADLLEEIRTTKK
LADDDKFAAAINGFKKVFVASE
>Mature_501_residues
SIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFANGVMGLAQNLEENNVGIIILGPYTE
IREGDEVRRTGRIMQVPVGEELIGRVVNPLGQPVDGLGPIHTTKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGR
GQRELIIGDRQTGKTAVALDTILNQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPYA
GVSMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIET
QAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSD
LDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVMILYALTRGFLDDIPVADITRFEEEFYAWLDSNAADLLEEIRTTKKL
ADDDKFAAAINGFKKVFVASE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=58.7301587301587, Blast_Score=600, Evalue=1e-172,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=58.7301587301587, Blast_Score=600, Evalue=1e-172,
Organism=Homo sapiens, GI19913428, Length=393, Percent_Identity=27.2264631043257, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI19913426, Length=393, Percent_Identity=26.972010178117, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI19913424, Length=235, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=54.3307086614173, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.4558823529412, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790170, Length=318, Percent_Identity=26.1006289308176, Blast_Score=101, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=478, Percent_Identity=59.8326359832636, Blast_Score=597, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988080, Length=478, Percent_Identity=59.8326359832636, Blast_Score=595, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988074, Length=478, Percent_Identity=55.6485355648536, Blast_Score=544, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17510931, Length=383, Percent_Identity=26.3707571801567, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=27.5167785234899, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=316, Percent_Identity=24.6835443037975, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=60.7843137254902, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=40.8450704225352, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=235, Percent_Identity=27.2340425531915, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=58.051689860835, Blast_Score=590, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319603, Length=304, Percent_Identity=27.9605263157895, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=427, Percent_Identity=26.6978922716628, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=57.8217821782178, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.2392026578073, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.2392026578073, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.2392026578073, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24638766, Length=316, Percent_Identity=26.8987341772152, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574560, Length=463, Percent_Identity=25.2699784017279, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24583988, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583986, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583984, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583992, Length=248, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129479, Length=238, Percent_Identity=26.890756302521, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54638; Mature: 54507

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFANGVM
CCCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHH
GLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGEELIGRVVNPLGQPVDGLGP
HHHHCCCCCCEEEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IHTTKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DTILNQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCC
AGVSMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
TSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CCHHHCCCCHHEEEHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
KQGLHKPLRVEKQVMILYALTRGFLDDIPVADITRFEEEFYAWLDSNAADLLEEIRTTKK
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LADDDKFAAAINGFKKVFVASE
HCCCHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFANGVM
CCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHH
GLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGEELIGRVVNPLGQPVDGLGP
HHHHCCCCCCEEEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IHTTKTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DTILNQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCC
AGVSMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
TSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CCHHHCCCCHHEEEHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
KQGLHKPLRVEKQVMILYALTRGFLDDIPVADITRFEEEFYAWLDSNAADLLEEIRTTKK
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LADDDKFAAAINGFKKVFVASE
HCCCHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]