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The map label for this gene is murA1 [H]

Identifier: 152977474

GI number: 152977474

Start: 3867093

End: 3868397

Strand: Reverse

Name: murA1 [H]

Synonym: Bcer98_3806

Alternate gene names: 152977474

Gene position: 3868397-3867093 (Counterclockwise)

Preceding gene: 152977475

Following gene: 152977473

Centisome position: 94.65

GC content: 41.15

Gene sequence:

>1305_bases
TTGGAAAAAATCATCGTCCGTGGCGGAAAGCGGTTGAACGGCACAGTGCGTGTTGAGGGCGCGAAAAATGCTGTATTACC
TATAATCGCTGCAGCCCTATTAGCGAGTGATGGAAAGAATGTACTATCTGAAGTACCAGTATTGTCTGATGTATACACAA
TCAATGAGGTATTACGTCATTTAAATGCTGAAGTCGTATTTGAAAATAACCAAGTAACAATCGATGCTTCAAAAGAGTTA
AAAATTGAAGCGCCGTTTGAATATGTACGTAAAATGCGTGCATCTGTCCAAGTAATGGGGCCATTATTAGCACGTAACGG
TCGCGCTCGCATTGCTCTTCCTGGTGGATGTGCAATCGGTTCACGTCCAATTGACCAACATTTAAAAGGCTTCGAAGCAA
TGGGAGCAAAAGTAAAAGTTGGTAATGGATTCGTTGAGGCATACGTAGAGGGAGAACTAAAAGGTGCAAAAATTTACTTA
GACTTCCCAAGCGTAGGTGCAACAGAAAATATTATGTCTGCTGCTGCATTAGCAAAAGGGACAACAATTATTGAAAACGC
TGCGAAAGAACCGGAAATTGTCGACTTAGCGAACTTCTTAAATGCAATGGGTGCTAAAGTACGCGGAGCTGGAACGGGAA
CAATTCGCATTGAAGGCGTTGATAAATTATATGGTACGCACCACTCTATTATTCCTGACCGTATTGAAGCGGGAACATTT
ATGGTTGCAGCAGCAATTACAGGTGGTAACATCTTAATTGAAAATGCAGTACCAGAACATCTACGCTCTGTTACGGCGAA
AATGGAAGAAATGGGTGTAAAAGTGATTGAGGAAAATGAAGGGTTACGTGTTATCGGTCCAGACAAATTAAAAGCCGTTG
ACATTAAAACAATGCCTCACCCAGGATTCCCAACAGATATGCAATCACAAATGATGGCATTATTATTACAAGCTGATGGA
ACAAGTATGATTACTGAGACGGTATTTGAGAACCGCTTCATGCATGTTGAGGAATTCCGTCGTATGAACGCGGATATTAA
AATTGAAGGTCGCTCTGTTATTATGAACGGACCGAATAATTTACAAGGTGCAGAAGTAGCAGCAACTGACTTACGTGCAG
CAGCTGCGTTAATTCTAGCTGGTTTAGTAGCAGAAGGTCACACTCGTGTAACCGAACTAAAGCATCTAGATCGTGGATAT
GTAAACTTCCATAAGAAACTAGCTGCATTAGGTGCAACGATTGAACGTATCAATGAACAAATGGAAGAAGTGAAAGAACA
AGAAGTTTCTGATCTTCATGCATAA

Upstream 100 bases:

>100_bases
TTCTACAGACAACAAAGATACAATTGTGGTTGGCACACCGATCATAACTTCTGAGTATTGAATGAATAGATATTGAAAAA
AGGACACGGAGGGGAATAAA

Downstream 100 bases:

>100_bases
TGATAATAGTCCCTATGTCTCATGACTGGGGGCTATTTTTTGTTCTATTACTGTTATAGTCAATTATCCCATGACTTATG
CATGTCTTACTTAAAAAATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
KIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVKVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAAALAKGTTIIENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGTHHSIIPDRIEAGTF
MVAAAITGGNILIENAVPEHLRSVTAKMEEMGVKVIEENEGLRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNNLQGAEVAATDLRAAAALILAGLVAEGHTRVTELKHLDRGY
VNFHKKLAALGATIERINEQMEEVKEQEVSDLHA

Sequences:

>Translated_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
KIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVKVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAAALAKGTTIIENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGTHHSIIPDRIEAGTF
MVAAAITGGNILIENAVPEHLRSVTAKMEEMGVKVIEENEGLRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNNLQGAEVAATDLRAAAALILAGLVAEGHTRVTELKHLDRGY
VNFHKKLAALGATIERINEQMEEVKEQEVSDLHA
>Mature_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
KIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVKVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAAALAKGTTIIENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGTHHSIIPDRIEAGTF
MVAAAITGGNILIENAVPEHLRSVTAKMEEMGVKVIEENEGLRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNNLQGAEVAATDLRAAAALILAGLVAEGHTRVTELKHLDRGY
VNFHKKLAALGATIERINEQMEEVKEQEVSDLHA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=52.3809523809524, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46840; Mature: 46840

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELKIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVKVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAAALAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTIIENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGTHHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHHHCCCCCCCCCHHCCCEE
MVAAAITGGNILIENAVPEHLRSVTAKMEEMGVKVIEENEGLRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNN
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVAATDLRAAAALILAGLVAEGHTRVTELKHLDRGYVNFHKKLAALGATIERINEQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
MEEVKEQEVSDLHA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELKIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVKVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAAALAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTIIENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGTHHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHHHCCCCCCCCCHHCCCEE
MVAAAITGGNILIENAVPEHLRSVTAKMEEMGVKVIEENEGLRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNN
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVAATDLRAAAALILAGLVAEGHTRVTELKHLDRGYVNFHKKLAALGATIERINEQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
MEEVKEQEVSDLHA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]