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The map label for this gene is moaE [H]

Identifier: 152977082

GI number: 152977082

Start: 3457065

End: 3457535

Strand: Reverse

Name: moaE [H]

Synonym: Bcer98_3392

Alternate gene names: 152977082

Gene position: 3457535-3457065 (Counterclockwise)

Preceding gene: 152977083

Following gene: 152977081

Centisome position: 84.6

GC content: 39.28

Gene sequence:

>471_bases
ATGACATATACGTATTATGAAGTAATTGATACACCGATTTCAATTGAAGAAGTAACAAATAAAGTGATTAGCCGAGAATG
CGGCGCAGTAACAACCTTTATTGGGACTGTTAGGGAATTTACGAAAGGGCGTCGTACATTATATTTAGAGTATGTCGCTT
ATAAAACAATGGCTGAAAAAATGCTTGCAAAAATTGGTGCGGAAGTGAAAGAAAAATGGCCAGGGACACATGTTGCGATT
ACGCATCGCACTGGTACACTTCAAATTTCTGATATCGCAGTTGTTGTTGCGGTATCAACACCGCATCGAAAAGCTGCTTA
TGAGGCGAATGAGTATATTATGGAACGCATCAAACAAATTGTGCCCATTTGGAAAAAAGAATTTTGGGAAGATGGCAATT
CGTGGATTGGTGATCAATTAGAAAGAGTATCGTATCCAGATGGAGAACCGGGAAAGGAGCTGGAATTATGA

Upstream 100 bases:

>100_bases
ATGAAGCGATTTTACAGTTACAAAAAACATATAAAATTTTTCATATAACAGATGCCGATTCTTATATGAAATGGCTTGTA
GAAATGGTAAGGGGTGCAAA

Downstream 100 bases:

>100_bases
TTCAAGTATTATTGTTCGCACATTTGCAAGAAGAAGCTGGAACAAGTGAATTGAAAATAGACTGTGACAACATAACAGTT
ACAGAGTTAAAACAGTTTCT

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTYTYYEVIDTPISIEEVTNKVISRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLAKIGAEVKEKWPGTHVAI
THRTGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGNSWIGDQLERVSYPDGEPGKELEL

Sequences:

>Translated_156_residues
MTYTYYEVIDTPISIEEVTNKVISRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLAKIGAEVKEKWPGTHVAI
THRTGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGNSWIGDQLERVSYPDGEPGKELEL
>Mature_155_residues
TYTYYEVIDTPISIEEVTNKVISRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLAKIGAEVKEKWPGTHVAIT
HRTGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGNSWIGDQLERVSYPDGEPGKELEL

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=41.7322834645669, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1787003, Length=137, Percent_Identity=37.2262773722628, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17509279, Length=129, Percent_Identity=34.1085271317829, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356259, Length=130, Percent_Identity=36.1538461538462, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17865; Mature: 17733

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTYYEVIDTPISIEEVTNKVISRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
MLAKIGAEVKEKWPGTHVAITHRTGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGNSWIGDQLERVSYPDGEPGKELEL
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYTYYEVIDTPISIEEVTNKVISRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
MLAKIGAEVKEKWPGTHVAITHRTGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGNSWIGDQLERVSYPDGEPGKELEL
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]