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The map label for this gene is citZ [H]

Identifier: 152976975

GI number: 152976975

Start: 3347213

End: 3348373

Strand: Reverse

Name: citZ [H]

Synonym: Bcer98_3278

Alternate gene names: 152976975

Gene position: 3348373-3347213 (Counterclockwise)

Preceding gene: 152976976

Following gene: 152976974

Centisome position: 81.93

GC content: 37.73

Gene sequence:

>1161_bases
GTGGATACAAGGTTGGGAGAATTTTCAGGAAAAGGAGAGAGTGTCATGACTGTTATTCGAGGTTTAGAAGGGGTAGTAGC
AACAACATCATCTGTGAGCTCAATTATTGATGATACATTAACGTATGTTGGGTATAATATTGATGATTTAGCAGAAAACG
CTACATTTGAAGAAGTCGTATACTTATTATGGAATCGCAGATTGCCTAATGAAGCTGAATTAGTGGAATTCAAGGAAACT
TTATCCAATTATTTGGAAGTTCCAAATGAGATTTTCACATATTTAAAGCAAGTAGACTTAAAGATTGCGCATCCGATGTC
AGTTTTACGAACAGCGATTTCCATGCTAGCATTATATGATGAGAGCGCTGAAATCATGGATGAACAGTCCAATCGTTTGA
AAGCGGTTAAATTACAAGCTCAAGTCGGAACAATTGTTGCAGCATACGCAAGAATTCGTAAAGGTTTAGAGGTTGTTGAA
CCAAGAAAAGATTTATCATTAGCAGCAAACTTCTTATACATGCTAAATAATCGTGAACCGAATGAAGTTGAAATTGAGGC
TTTTGATAAGGCGCTTGTCCTTCATGCAGACCATGAATTAAACGCTTCTACATTTACAGCGCGCGTTTGTGTTGCTACAC
TTTCAGATGTATATTCTGGTATCACAGCAGCGATTGGCGCGCTAAAAGGGCCTCTTCATGGCGGGGCAAATGAAAATGTA
ATGAAGATGCTAAAAGAAATTGGTGAAGAAGAAAATGTAGAATCCTATATTCATAATGCGCTTCAAAATAAAGTGAAGAT
TATGGGATTTGGTCATCGTGTATATGAACATGGTGATCCACGTGCAAAACATTTACGTGAAATGTCTAAGAGATTATGCG
TGCTTTTAGGAGAAGAGAAATGGTATAATATGTCTGTGAAAATAGAAGAGATTGTAACAAGAGAAAAAGCTCTTCCGCCA
AATGTCGATTTCTACTCTGCTTCTGTATACCATTGTTTAGGAATTGACCATGATTTATTTACACCAATTTTTGCGATTAG
CCGCATGTCAGGCTGGTTAGCTCATATTTTAGAACAATATGAAAATAACCGTTTAATTCGCCCGCGTGCTGAATATAGTG
GACCGACGCATCAAAGATACGTTCCGCTAGCACAACGCTAA

Upstream 100 bases:

>100_bases
AATAGAACTTACATGATGGGGATATCACAACAAGTTGCATGATCGTGCATTTTGCTTGTCTAAAGAGTGAACGGGCGTTC
ATAATTTAGAAGGAGCGCAA

Downstream 100 bases:

>100_bases
GTAAAAAGCACTATTTCGATAGTAGAAATAAACCTTTAAAAGTCTGACTGTTTAGGAAAGAAGTAATGATTGGAATATTT
TAATTTGACTAACGGTTTGA

Product: citrate synthase

Products: NA

Alternate protein names: Citrate synthase II [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDTRLGEFSGKGESVMTVIRGLEGVVATTSSVSSIIDDTLTYVGYNIDDLAENATFEEVVYLLWNRRLPNEAELVEFKET
LSNYLEVPNEIFTYLKQVDLKIAHPMSVLRTAISMLALYDESAEIMDEQSNRLKAVKLQAQVGTIVAAYARIRKGLEVVE
PRKDLSLAANFLYMLNNREPNEVEIEAFDKALVLHADHELNASTFTARVCVATLSDVYSGITAAIGALKGPLHGGANENV
MKMLKEIGEEENVESYIHNALQNKVKIMGFGHRVYEHGDPRAKHLREMSKRLCVLLGEEKWYNMSVKIEEIVTREKALPP
NVDFYSASVYHCLGIDHDLFTPIFAISRMSGWLAHILEQYENNRLIRPRAEYSGPTHQRYVPLAQR

Sequences:

>Translated_386_residues
MDTRLGEFSGKGESVMTVIRGLEGVVATTSSVSSIIDDTLTYVGYNIDDLAENATFEEVVYLLWNRRLPNEAELVEFKET
LSNYLEVPNEIFTYLKQVDLKIAHPMSVLRTAISMLALYDESAEIMDEQSNRLKAVKLQAQVGTIVAAYARIRKGLEVVE
PRKDLSLAANFLYMLNNREPNEVEIEAFDKALVLHADHELNASTFTARVCVATLSDVYSGITAAIGALKGPLHGGANENV
MKMLKEIGEEENVESYIHNALQNKVKIMGFGHRVYEHGDPRAKHLREMSKRLCVLLGEEKWYNMSVKIEEIVTREKALPP
NVDFYSASVYHCLGIDHDLFTPIFAISRMSGWLAHILEQYENNRLIRPRAEYSGPTHQRYVPLAQR
>Mature_386_residues
MDTRLGEFSGKGESVMTVIRGLEGVVATTSSVSSIIDDTLTYVGYNIDDLAENATFEEVVYLLWNRRLPNEAELVEFKET
LSNYLEVPNEIFTYLKQVDLKIAHPMSVLRTAISMLALYDESAEIMDEQSNRLKAVKLQAQVGTIVAAYARIRKGLEVVE
PRKDLSLAANFLYMLNNREPNEVEIEAFDKALVLHADHELNASTFTARVCVATLSDVYSGITAAIGALKGPLHGGANENV
MKMLKEIGEEENVESYIHNALQNKVKIMGFGHRVYEHGDPRAKHLREMSKRLCVLLGEEKWYNMSVKIEEIVTREKALPP
NVDFYSASVYHCLGIDHDLFTPIFAISRMSGWLAHILEQYENNRLIRPRAEYSGPTHQRYVPLAQR

Specific function: Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect [H]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=374, Percent_Identity=25.9358288770053, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786527, Length=368, Percent_Identity=36.9565217391304, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1786939, Length=379, Percent_Identity=34.8284960422164, Blast_Score=211, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17555174, Length=378, Percent_Identity=26.984126984127, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319850, Length=381, Percent_Identity=23.8845144356955, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324328, Length=387, Percent_Identity=22.7390180878553, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325257, Length=180, Percent_Identity=31.1111111111111, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640126, Length=376, Percent_Identity=26.5957446808511, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640124, Length=376, Percent_Identity=26.5957446808511, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356863, Length=380, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 43583; Mature: 43583

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRLGEFSGKGESVMTVIRGLEGVVATTSSVSSIIDDTLTYVGYNIDDLAENATFEEVV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHH
YLLWNRRLPNEAELVEFKETLSNYLEVPNEIFTYLKQVDLKIAHPMSVLRTAISMLALYD
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
ESAEIMDEQSNRLKAVKLQAQVGTIVAAYARIRKGLEVVEPRKDLSLAANFLYMLNNREP
CHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCC
NEVEIEAFDKALVLHADHELNASTFTARVCVATLSDVYSGITAAIGALKGPLHGGANENV
CEEEHEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MKMLKEIGEEENVESYIHNALQNKVKIMGFGHRVYEHGDPRAKHLREMSKRLCVLLGEEK
HHHHHHHCCCCCHHHHHHHHHHCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHEEECCCC
WYNMSVKIEEIVTREKALPPNVDFYSASVYHCLGIDHDLFTPIFAISRMSGWLAHILEQY
CEEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ENNRLIRPRAEYSGPTHQRYVPLAQR
CCCCEECCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTRLGEFSGKGESVMTVIRGLEGVVATTSSVSSIIDDTLTYVGYNIDDLAENATFEEVV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHH
YLLWNRRLPNEAELVEFKETLSNYLEVPNEIFTYLKQVDLKIAHPMSVLRTAISMLALYD
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
ESAEIMDEQSNRLKAVKLQAQVGTIVAAYARIRKGLEVVEPRKDLSLAANFLYMLNNREP
CHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCC
NEVEIEAFDKALVLHADHELNASTFTARVCVATLSDVYSGITAAIGALKGPLHGGANENV
CEEEHEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MKMLKEIGEEENVESYIHNALQNKVKIMGFGHRVYEHGDPRAKHLREMSKRLCVLLGEEK
HHHHHHHCCCCCHHHHHHHHHHCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHEEECCCC
WYNMSVKIEEIVTREKALPPNVDFYSASVYHCLGIDHDLFTPIFAISRMSGWLAHILEQY
CEEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ENNRLIRPRAEYSGPTHQRYVPLAQR
CCCCEECCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045898; 9387221; 9384377 [H]