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The map label for this gene is comEA [H]

Identifier: 152976757

GI number: 152976757

Start: 3101234

End: 3101836

Strand: Reverse

Name: comEA [H]

Synonym: Bcer98_3053

Alternate gene names: 152976757

Gene position: 3101836-3101234 (Counterclockwise)

Preceding gene: 152976759

Following gene: 152976756

Centisome position: 75.89

GC content: 36.32

Gene sequence:

>603_bases
ATGATGTGGAATTTACAAAAGAAGTGGTTAGCTTTATTAGGAGCTGCTGGATGTGTGATTGTTCTTTTTTTATGGCAGAC
AAACAATCAAGAAGAGAAAGCAACGGTTCAACTTCAATCAGCGACAGCTATGAAACGCGAAGAGAAAAATAAATCAAAAG
AATTGGAAACAAAAGAGCAGAAAAAAGAAATTATAGTTGATATAAAAGGGGCTGTGCAAAGAGAGGGAGTTTATGAGCTA
AGAGAAGGTTCTCGCGTGAAAGATGGTATTGAAAAAGCAGGAGGGTTTTTGCCAGAAGCGGATGTAACACAAGTAAATTT
AGCTCAAATTATGCAGGATCAAATGCTTTTATATATTCCTAAAAAAGGAGAACGATTACATGAAACAACGCTACCGGTTC
AACAATCTGGAAAGATATCGATCAATCAAGCTTCAAAAGAACAGCTTGAAAACATAACAGGAATCGGTCCGAGGAAAGCG
GAGGCAATTATAAAATATCGCGAAGAGCATGGAGCATTTCAAAAGATAGAAGATTTGTTGGAGATAGATGGGATTGGAGA
GAAATCACTTGAAAAGATGAAAGATCAAATTATGATTCCATAA

Upstream 100 bases:

>100_bases
TCCCTATGATTCCGATGTTCAATGTTTCATCCCTCCTTCGTAACATCTTTCTCCTAAACAATATGAACTATGTTGTGAAT
TTATGAATGGGAGGAATAAA

Downstream 100 bases:

>100_bases
AGCAAAACGGGAGTCGTACCATATGAATTTCAAAAGATGAAAGGAGTGTAAAGCCCTCTTTGATTATACGACTGCAAATT
TTATGGGAATATAATAAAAT

Product: helix-hairpin-helix repeat-containing competence protein ComEA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MMWNLQKKWLALLGAAGCVIVLFLWQTNNQEEKATVQLQSATAMKREEKNKSKELETKEQKKEIIVDIKGAVQREGVYEL
REGSRVKDGIEKAGGFLPEADVTQVNLAQIMQDQMLLYIPKKGERLHETTLPVQQSGKISINQASKEQLENITGIGPRKA
EAIIKYREEHGAFQKIEDLLEIDGIGEKSLEKMKDQIMIP

Sequences:

>Translated_200_residues
MMWNLQKKWLALLGAAGCVIVLFLWQTNNQEEKATVQLQSATAMKREEKNKSKELETKEQKKEIIVDIKGAVQREGVYEL
REGSRVKDGIEKAGGFLPEADVTQVNLAQIMQDQMLLYIPKKGERLHETTLPVQQSGKISINQASKEQLENITGIGPRKA
EAIIKYREEHGAFQKIEDLLEIDGIGEKSLEKMKDQIMIP
>Mature_200_residues
MMWNLQKKWLALLGAAGCVIVLFLWQTNNQEEKATVQLQSATAMKREEKNKSKELETKEQKKEIIVDIKGAVQREGVYEL
REGSRVKDGIEKAGGFLPEADVTQVNLAQIMQDQMLLYIPKKGERLHETTLPVQQSGKISINQASKEQLENITGIGPRKA
EAIIKYREEHGAFQKIEDLLEIDGIGEKSLEKMKDQIMIP

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 22660; Mature: 22660

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWNLQKKWLALLGAAGCVIVLFLWQTNNQEEKATVQLQSATAMKREEKNKSKELETKEQ
CCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHH
KKEIIVDIKGAVQREGVYELREGSRVKDGIEKAGGFLPEADVTQVNLAQIMQDQMLLYIP
HHHEEEEHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEC
KKGERLHETTLPVQQSGKISINQASKEQLENITGIGPRKAEAIIKYREEHGAFQKIEDLL
CCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHH
EIDGIGEKSLEKMKDQIMIP
HHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MMWNLQKKWLALLGAAGCVIVLFLWQTNNQEEKATVQLQSATAMKREEKNKSKELETKEQ
CCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHH
KKEIIVDIKGAVQREGVYELREGSRVKDGIEKAGGFLPEADVTQVNLAQIMQDQMLLYIP
HHHEEEEHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEC
KKGERLHETTLPVQQSGKISINQASKEQLENITGIGPRKAEAIIKYREEHGAFQKIEDLL
CCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHH
EIDGIGEKSLEKMKDQIMIP
HHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]