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The map label for this gene is yqgF [H]

Identifier: 152976706

GI number: 152976706

Start: 3048894

End: 3051011

Strand: Reverse

Name: yqgF [H]

Synonym: Bcer98_3001

Alternate gene names: 152976706

Gene position: 3051011-3048894 (Counterclockwise)

Preceding gene: 152976707

Following gene: 152976705

Centisome position: 74.65

GC content: 37.2

Gene sequence:

>2118_bases
ATGAGTAAGAAAAAAAAGAAAAAGACCCACGTTCCGTTTCGGCTGAACGTGTTATTTCTTTGTGTATTTTTAATGTTCTC
TGCGGTTATTGTAAGGCTTGGTTATGTACAAATTGTTCATGGGGAGGAGTACAAAAACGAAGTTGAGAAAAAAGAAAACT
CAACAATTAGTAATCCGGTTCCACGTGGAAAAATATTTGACCGATATGGCCGTTCCGTTGTAGATAATGATCCAGTTCGA
ACCATTACATTTACGCGAATGAAAGGGTCGACTTCAGAGGAACGTTTAGAAACAGCGAAAAAGCTTGCAGATTTAATTGA
AGTATCACCGGATAAATTAACAGAACGTGATAAAAAAGATTATTGGCTGTTCCTTCATAAAGAAGAAGCGAAAGCAAAAA
TTACAAAAAAAGATCGCGAAGAATTAAAAGAAAAAAAAATTGATGATAAAGAAGTCGCAGAGCGTCAACGAAATCGTGTG
ACGGAAGAAGAATTAAATCAATTAACAGAAAAAGATTTAGAAGTGCTGGCGATTAAGAGTAAGATGGACGGCGGATATGC
TATGACGCCGCAAATTATTAAAAAGCAAGTAACCCCGAAAGAATACGCTGTAGTCAGCGAGCGTTTAGCGTTATTACCAG
GTGTCGATACAAATGTGGATTGGGATCGTAAATATACGTATGATGATATGTTCCGCAGTGTACTTGGTGGTGTAACAAGC
TCGGATGAAGGGTTACCAAAAGAACGCTTAGATTATTTCCTTGTTCGGGATTATAACCGTAATGATCGAGTTGGAAAAAG
TTATATTGAACAACAATATGAAGATGCACTTCACGGTTCAAAGGCAGAAGTGAAGAATATTACAGATAAAAATGGTAATA
TTTTAGAAACAGTAAATGTCTTGAAAGGGCAACGAGGAAATGATCTAAATTTAACAATTGACATGGAACTGCAAAAACGT
GTCGAAGAAATTATTGGAAAATATTTAATGAAATTTAAAGGTTCAGAGCCTCTGCTTGATCGAGCGTTTGTTGTAATGAT
GAATCCGAAAAACGGTGAAATTCTGTCAATGGCTGGGAAACAGCTTGTCAATGAAGATGGGAAAACAGAAGTGAAGGACT
TTGCTTTAGGTACAATGACAAGTTCTTATCCAATGGGGTCGACTGTCAAAGGTGCAACTTTGTTAACTGGATATCAAACA
GGTGCCATTACACCTGGAACAACTTTATTGGATGAACCGATCAAATTAAAAGGGACACCGACGAAATCTTCTTGGAAAAC
GATGGGTTATATTAATGATTTAACTGCTTTAAAGATGTCTTCTAACGTATATATGTTTAAAACAGCGATGAATATTGCAA
AAGTACCTTACATTCGTGGAGGTACATTAGATATTAAAAAACAAGCGTTTGATGATATGCGTTATTACTTTAGTCAGTTT
GGTCTAGGAGTGAAAACAGGTATCGACTTACCGAATGAATCAGCTGGACTTCAAGGTTCGCAGTATACACCTGGTTTCTT
GTTAGACTTAGCGATTGGCCAGTATGATAACTATACACCACTTCAGCTTGCACAATATGTATCTACAATTGCAAATGGTG
GCTATCGTATGCAACCGCAAATTGTAAAAGAAATTCGTCAACCAGCAGCGAAACCTGATGAAGTTGGAAAAGTCATTCAA
TCAATGGAACCGAAAGTATTGAACCGTATTGATATGCCTGAGAGTCAGATTAAACGAATTCAAGAAGGGTTTAGGCAAGT
GTTTAATGATGCGAGTGGTACTGGCAAGAGATACTTTGCGACTGCAAAGTATCAAGCTGCCGGAAAAACAGGAACTGCTC
AAATACCATACGGTGGTGACAAAGAAATTGGAAAAGATGCAAATGGTCAGCGTAAAATAATTTATAACTTAACGTTAGTA
GGGTATGCACCATTTGATAATCCAGAAGTTGCCTTCTCCGTTGTTGTTCCGTGGGTATATGATGATAAAACAGGAATTAA
CGGATACATTGGTCGTGAAATTCTGGATGCTTACTTTGATTTGAAAAAGCAAGCATTAACAGGTGAAGAGCCGCAAGATG
AAAAAGGGGAAAAATCAAAGAAACAAGATGATGAATAA

Upstream 100 bases:

>100_bases
TTTTATGCTAGAATAAAAAGACACGTAAAATAGCTGTAAGGGCACCTGTAACAGGTGTCCCTTTCATATTATATAGCTAA
AGGTGGTAGAGGGGGTTCGT

Downstream 100 bases:

>100_bases
ATTGATATCAGTTTGGCACACTATCTCAAAAGATAGTGTGCTTTTTTTGTAAGTGATACATATATTTTAGTAATGATGGA
CAAGTCCAGAAAATGCAATT

Product: penicillin-binding protein transpeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MSKKKKKKTHVPFRLNVLFLCVFLMFSAVIVRLGYVQIVHGEEYKNEVEKKENSTISNPVPRGKIFDRYGRSVVDNDPVR
TITFTRMKGSTSEERLETAKKLADLIEVSPDKLTERDKKDYWLFLHKEEAKAKITKKDREELKEKKIDDKEVAERQRNRV
TEEELNQLTEKDLEVLAIKSKMDGGYAMTPQIIKKQVTPKEYAVVSERLALLPGVDTNVDWDRKYTYDDMFRSVLGGVTS
SDEGLPKERLDYFLVRDYNRNDRVGKSYIEQQYEDALHGSKAEVKNITDKNGNILETVNVLKGQRGNDLNLTIDMELQKR
VEEIIGKYLMKFKGSEPLLDRAFVVMMNPKNGEILSMAGKQLVNEDGKTEVKDFALGTMTSSYPMGSTVKGATLLTGYQT
GAITPGTTLLDEPIKLKGTPTKSSWKTMGYINDLTALKMSSNVYMFKTAMNIAKVPYIRGGTLDIKKQAFDDMRYYFSQF
GLGVKTGIDLPNESAGLQGSQYTPGFLLDLAIGQYDNYTPLQLAQYVSTIANGGYRMQPQIVKEIRQPAAKPDEVGKVIQ
SMEPKVLNRIDMPESQIKRIQEGFRQVFNDASGTGKRYFATAKYQAAGKTGTAQIPYGGDKEIGKDANGQRKIIYNLTLV
GYAPFDNPEVAFSVVVPWVYDDKTGINGYIGREILDAYFDLKKQALTGEEPQDEKGEKSKKQDDE

Sequences:

>Translated_705_residues
MSKKKKKKTHVPFRLNVLFLCVFLMFSAVIVRLGYVQIVHGEEYKNEVEKKENSTISNPVPRGKIFDRYGRSVVDNDPVR
TITFTRMKGSTSEERLETAKKLADLIEVSPDKLTERDKKDYWLFLHKEEAKAKITKKDREELKEKKIDDKEVAERQRNRV
TEEELNQLTEKDLEVLAIKSKMDGGYAMTPQIIKKQVTPKEYAVVSERLALLPGVDTNVDWDRKYTYDDMFRSVLGGVTS
SDEGLPKERLDYFLVRDYNRNDRVGKSYIEQQYEDALHGSKAEVKNITDKNGNILETVNVLKGQRGNDLNLTIDMELQKR
VEEIIGKYLMKFKGSEPLLDRAFVVMMNPKNGEILSMAGKQLVNEDGKTEVKDFALGTMTSSYPMGSTVKGATLLTGYQT
GAITPGTTLLDEPIKLKGTPTKSSWKTMGYINDLTALKMSSNVYMFKTAMNIAKVPYIRGGTLDIKKQAFDDMRYYFSQF
GLGVKTGIDLPNESAGLQGSQYTPGFLLDLAIGQYDNYTPLQLAQYVSTIANGGYRMQPQIVKEIRQPAAKPDEVGKVIQ
SMEPKVLNRIDMPESQIKRIQEGFRQVFNDASGTGKRYFATAKYQAAGKTGTAQIPYGGDKEIGKDANGQRKIIYNLTLV
GYAPFDNPEVAFSVVVPWVYDDKTGINGYIGREILDAYFDLKKQALTGEEPQDEKGEKSKKQDDE
>Mature_704_residues
SKKKKKKTHVPFRLNVLFLCVFLMFSAVIVRLGYVQIVHGEEYKNEVEKKENSTISNPVPRGKIFDRYGRSVVDNDPVRT
ITFTRMKGSTSEERLETAKKLADLIEVSPDKLTERDKKDYWLFLHKEEAKAKITKKDREELKEKKIDDKEVAERQRNRVT
EEELNQLTEKDLEVLAIKSKMDGGYAMTPQIIKKQVTPKEYAVVSERLALLPGVDTNVDWDRKYTYDDMFRSVLGGVTSS
DEGLPKERLDYFLVRDYNRNDRVGKSYIEQQYEDALHGSKAEVKNITDKNGNILETVNVLKGQRGNDLNLTIDMELQKRV
EEIIGKYLMKFKGSEPLLDRAFVVMMNPKNGEILSMAGKQLVNEDGKTEVKDFALGTMTSSYPMGSTVKGATLLTGYQTG
AITPGTTLLDEPIKLKGTPTKSSWKTMGYINDLTALKMSSNVYMFKTAMNIAKVPYIRGGTLDIKKQAFDDMRYYFSQFG
LGVKTGIDLPNESAGLQGSQYTPGFLLDLAIGQYDNYTPLQLAQYVSTIANGGYRMQPQIVKEIRQPAAKPDEVGKVIQS
MEPKVLNRIDMPESQIKRIQEGFRQVFNDASGTGKRYFATAKYQAAGKTGTAQIPYGGDKEIGKDANGQRKIIYNLTLVG
YAPFDNPEVAFSVVVPWVYDDKTGINGYIGREILDAYFDLKKQALTGEEPQDEKGEKSKKQDDE

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=642, Percent_Identity=23.6760124610592, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786272, Length=402, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 79641; Mature: 79510

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKKKKKTHVPFRLNVLFLCVFLMFSAVIVRLGYVQIVHGEEYKNEVEKKENSTISNPV
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCCCC
PRGKIFDRYGRSVVDNDPVRTITFTRMKGSTSEERLETAKKLADLIEVSPDKLTERDKKD
CCCHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
YWLFLHKEEAKAKITKKDREELKEKKIDDKEVAERQRNRVTEEELNQLTEKDLEVLAIKS
EEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEE
KMDGGYAMTPQIIKKQVTPKEYAVVSERLALLPGVDTNVDWDRKYTYDDMFRSVLGGVTS
CCCCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
SDEGLPKERLDYFLVRDYNRNDRVGKSYIEQQYEDALHGSKAEVKNITDKNGNILETVNV
CCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHH
LKGQRGNDLNLTIDMELQKRVEEIIGKYLMKFKGSEPLLDRAFVVMMNPKNGEILSMAGK
HCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHH
QLVNEDGKTEVKDFALGTMTSSYPMGSTVKGATLLTGYQTGAITPGTTLLDEPIKLKGTP
HHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHCCCCEEECCCC
TKSSWKTMGYINDLTALKMSSNVYMFKTAMNIAKVPYIRGGTLDIKKQAFDDMRYYFSQF
CCCCCHHHHHHHHHHHEEECCCEEEEEEHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHH
GLGVKTGIDLPNESAGLQGSQYTPGFLLDLAIGQYDNYTPLQLAQYVSTIANGGYRMQPQ
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECHH
IVKEIRQPAAKPDEVGKVIQSMEPKVLNRIDMPESQIKRIQEGFRQVFNDASGTGKRYFA
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
TAKYQAAGKTGTAQIPYGGDKEIGKDANGQRKIIYNLTLVGYAPFDNPEVAFSVVVPWVY
EEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCEEEEEEEEEEE
DDKTGINGYIGREILDAYFDLKKQALTGEEPQDEKGEKSKKQDDE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKKKKKKTHVPFRLNVLFLCVFLMFSAVIVRLGYVQIVHGEEYKNEVEKKENSTISNPV
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCCCC
PRGKIFDRYGRSVVDNDPVRTITFTRMKGSTSEERLETAKKLADLIEVSPDKLTERDKKD
CCCHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
YWLFLHKEEAKAKITKKDREELKEKKIDDKEVAERQRNRVTEEELNQLTEKDLEVLAIKS
EEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEE
KMDGGYAMTPQIIKKQVTPKEYAVVSERLALLPGVDTNVDWDRKYTYDDMFRSVLGGVTS
CCCCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
SDEGLPKERLDYFLVRDYNRNDRVGKSYIEQQYEDALHGSKAEVKNITDKNGNILETVNV
CCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHH
LKGQRGNDLNLTIDMELQKRVEEIIGKYLMKFKGSEPLLDRAFVVMMNPKNGEILSMAGK
HCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHH
QLVNEDGKTEVKDFALGTMTSSYPMGSTVKGATLLTGYQTGAITPGTTLLDEPIKLKGTP
HHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHCCCCEEECCCC
TKSSWKTMGYINDLTALKMSSNVYMFKTAMNIAKVPYIRGGTLDIKKQAFDDMRYYFSQF
CCCCCHHHHHHHHHHHEEECCCEEEEEEHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHH
GLGVKTGIDLPNESAGLQGSQYTPGFLLDLAIGQYDNYTPLQLAQYVSTIANGGYRMQPQ
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECHH
IVKEIRQPAAKPDEVGKVIQSMEPKVLNRIDMPESQIKRIQEGFRQVFNDASGTGKRYFA
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
TAKYQAAGKTGTAQIPYGGDKEIGKDANGQRKIIYNLTLVGYAPFDNPEVAFSVVVPWVY
EEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCEEEEEEEEEEE
DDKTGINGYIGREILDAYFDLKKQALTGEEPQDEKGEKSKKQDDE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]