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The map label for this gene is glmU [H]

Identifier: 152976700

GI number: 152976700

Start: 3041527

End: 3043884

Strand: Reverse

Name: glmU [H]

Synonym: Bcer98_2995

Alternate gene names: 152976700

Gene position: 3043884-3041527 (Counterclockwise)

Preceding gene: 152976701

Following gene: 152976699

Centisome position: 74.48

GC content: 36.43

Gene sequence:

>2358_bases
ATGTGCATGAAGGGGGTTATTTTAGCTGGTGGAAAAGGAAGGCGCCTAAGACCGTTAACATGTAATGTTCCAAAACCGAT
GTTACCATTACTAGAGAAACCGGTTTTAGAATATAACATTGAATTGTTACGGCGACATGGTATTCGGGAAATCGCAATTA
CTGTTCAATATTTGAGCAATACGATTAGAGAGTACTTTGGGGATGGGAGTAAATGGGGCGTCAAATTACATTACTTTGAG
GATTCACCCCCCCTTGGTACAGCAGGAAGTATTAAACAGGCTGAAGCATTTTTAGATGAACCGTTTGTAGTAATTAGCGG
TGATGCATTAACAGATTTTCCATTAACAGAAGGGATTGTATTTCACCAACAGAAGAAGAGAATGCTAACGATGTTTGTAA
AAGAAGTAGAAAATCCACTGTCTTTTGGGTTAGTGGTGATGAATAAAGAACAAGAAATTATACGTTATATGGAGAAACCG
AGTTGGAATGAAGTCATTTCAAACGTTGTAAACACAGGGATTTATATTATGGATCCTAGTATTTTTTCTTATATACCTCC
CAAAACATATGCTGATTTTAGTCGCCATATCTTTCCGTTATTGGAGAATACAAATGCGTTATTTGGATACAAAGCAGAAG
GATACTGGATGGATATTGGAACATTTGAGCAGTATCGGCAAGCTCAATTTGATTTATTGACGAAAAAAGTGAATGTAACG
ATTCCTTATACAGAAGTATTACCGATGGTTTGGATGGGAGAAGCAGTAACGATTGAAAAAGGTACAAAGATTCACGGGCC
ATCTTTCATCGGTGACGGAGTAACAATCGGAGCGGGAGCGATCGTTGAACCGTATTCTATTATTGGGAAACATAGTACTG
TATCAAGCTACACACGTCTTCAAAAAAGTATTATTTTCGCCAATACGTATATTGGGAAACATTGTGAATTATTAGAGACG
ACAGTTGGTGAAAAAACGAGACTCGAAGACGATGTCACGCTATATCAGAAAAGTGTTGTAGCGGATTGTTGTCAAATCGG
GAAAAGCACTGTAATTAAGCAAGGTGGGAAGTTATGGCCTCATAAAATAATTGATCATCATTCTATTATTGCATCTGGTG
GTGTTACAAAAGAAGAACATGCATCAAGGTGGTTGCAAAGAAGTCAAATTGTAGGTAGAGGAAATATCGAAATAACACCG
CAAATCATTGTGAAAATAGCAATGGCTTACGGTTCATTGTTTCGGAAGGGTGAGACTATATTAATAGGAAGCTATAAGAA
TGCAGAAGTACAAGTTTTTAAAAAATTATTTCTGCATGCGCTTCACAGCGTAGGAATGAATACGGTGGAATGTCAAGAAA
TGAATGAATCCCCATTTCAATATACGATTCGGAAATTAGAATGCATAGGTGGTGCGTTCATTTGTTTTACGAAAGATCAA
GATATGAGGATACGGTTCTATGGGAAAGAAGGAAGGCAGTTAACTTATAAGCAGCAGAAGGAAATAGAAAATTTATATAT
GGCTGAAAACTTTCGCTATGTATCTGAAAAAGAGATAGGAGAAAATCAAATAATACAAATTTGTTTAGAGGATTATGTAA
CGGCCGTTTTAGAATATATAGATGTTGAGAACATACAGGCGCAACAGTTCCACCTTCTTATTAATAAAATGGATTGTTTG
TTACAACCGTTACTTCTTTCTTTTTTTCAAAGGCTTGGTTGTTCTATTACATGGGTGTATGCGCAGGAGCGGAAAGAACA
TGTGAAATCTTTAATGAAATCCAGTCATTCTAATATGGCCTTTATATGCGGTGAAGAAGGAAATGTATTCGAATTATATG
ATGGGCATGGTAGGGTGTATCAGAGTGAGAATGTTAGCGAAATCGATGTGTCAGACTTATTATTGAAAACAGTCGAGGAT
ATGTATCCAATATCGTTAAAGCTAGGAAATTGTTATCTTCTCTTTTATATGCACATGGAAAAAGAATTGCGACAAGTGTG
GCAAAGGGATATGTTATATCGGATTGGGAAGTTACTCGAGTTAATTGCAAAACAAGGGAGTACATTATCCATGATGGTAG
AACAGACAGCACCGCTTTATTTGTTATGTGATGAGGTTGTTTGTTCGTGGAATGAAAAAGGGAAAATAATGGGGATGTTA
CTGCAAGATATGGGAGAAAGGGAAATAGAAATATTAGAAGGAGTTCAGTTTAAATATGCAGAGAAAGAATGGTCGTACAT
TGTTTCTGATGTGAAACAACCGAAATTTCTTGTATACTCACATGCGAAAAACCCACTAGTAGCAAGAGAAAATATGAAAA
ATCTTATAGAAAAGATTAGACAATATCAAAAGGTGTAG

Upstream 100 bases:

>100_bases
GTTTTCTAAGGTGGTTTAGACATTGGAAAGATTAACGGACATAGAAGTCACATACATATGGTAAATAAAGATGATTTCAT
ATTACAAAAGTGGAGGATGA

Downstream 100 bases:

>100_bases
AATTTTTGTTTTAAAAGTGGTATTATGGTATAGTCTGATTTAAGTTATTAGTGACTGGAGGGAAATAAGAATGCGTGTGA
ATATTACTCTAGCATGTACA

Product: nucleotidyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MCMKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQYLSNTIREYFGDGSKWGVKLHYFE
DSPPLGTAGSIKQAEAFLDEPFVVISGDALTDFPLTEGIVFHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKP
SWNEVISNVVNTGIYIMDPSIFSYIPPKTYADFSRHIFPLLENTNALFGYKAEGYWMDIGTFEQYRQAQFDLLTKKVNVT
IPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPYSIIGKHSTVSSYTRLQKSIIFANTYIGKHCELLET
TVGEKTRLEDDVTLYQKSVVADCCQIGKSTVIKQGGKLWPHKIIDHHSIIASGGVTKEEHASRWLQRSQIVGRGNIEITP
QIIVKIAMAYGSLFRKGETILIGSYKNAEVQVFKKLFLHALHSVGMNTVECQEMNESPFQYTIRKLECIGGAFICFTKDQ
DMRIRFYGKEGRQLTYKQQKEIENLYMAENFRYVSEKEIGENQIIQICLEDYVTAVLEYIDVENIQAQQFHLLINKMDCL
LQPLLLSFFQRLGCSITWVYAQERKEHVKSLMKSSHSNMAFICGEEGNVFELYDGHGRVYQSENVSEIDVSDLLLKTVED
MYPISLKLGNCYLLFYMHMEKELRQVWQRDMLYRIGKLLELIAKQGSTLSMMVEQTAPLYLLCDEVVCSWNEKGKIMGML
LQDMGEREIEILEGVQFKYAEKEWSYIVSDVKQPKFLVYSHAKNPLVARENMKNLIEKIRQYQKV

Sequences:

>Translated_785_residues
MCMKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQYLSNTIREYFGDGSKWGVKLHYFE
DSPPLGTAGSIKQAEAFLDEPFVVISGDALTDFPLTEGIVFHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKP
SWNEVISNVVNTGIYIMDPSIFSYIPPKTYADFSRHIFPLLENTNALFGYKAEGYWMDIGTFEQYRQAQFDLLTKKVNVT
IPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPYSIIGKHSTVSSYTRLQKSIIFANTYIGKHCELLET
TVGEKTRLEDDVTLYQKSVVADCCQIGKSTVIKQGGKLWPHKIIDHHSIIASGGVTKEEHASRWLQRSQIVGRGNIEITP
QIIVKIAMAYGSLFRKGETILIGSYKNAEVQVFKKLFLHALHSVGMNTVECQEMNESPFQYTIRKLECIGGAFICFTKDQ
DMRIRFYGKEGRQLTYKQQKEIENLYMAENFRYVSEKEIGENQIIQICLEDYVTAVLEYIDVENIQAQQFHLLINKMDCL
LQPLLLSFFQRLGCSITWVYAQERKEHVKSLMKSSHSNMAFICGEEGNVFELYDGHGRVYQSENVSEIDVSDLLLKTVED
MYPISLKLGNCYLLFYMHMEKELRQVWQRDMLYRIGKLLELIAKQGSTLSMMVEQTAPLYLLCDEVVCSWNEKGKIMGML
LQDMGEREIEILEGVQFKYAEKEWSYIVSDVKQPKFLVYSHAKNPLVARENMKNLIEKIRQYQKV
>Mature_785_residues
MCMKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQYLSNTIREYFGDGSKWGVKLHYFE
DSPPLGTAGSIKQAEAFLDEPFVVISGDALTDFPLTEGIVFHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKP
SWNEVISNVVNTGIYIMDPSIFSYIPPKTYADFSRHIFPLLENTNALFGYKAEGYWMDIGTFEQYRQAQFDLLTKKVNVT
IPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPYSIIGKHSTVSSYTRLQKSIIFANTYIGKHCELLET
TVGEKTRLEDDVTLYQKSVVADCCQIGKSTVIKQGGKLWPHKIIDHHSIIASGGVTKEEHASRWLQRSQIVGRGNIEITP
QIIVKIAMAYGSLFRKGETILIGSYKNAEVQVFKKLFLHALHSVGMNTVECQEMNESPFQYTIRKLECIGGAFICFTKDQ
DMRIRFYGKEGRQLTYKQQKEIENLYMAENFRYVSEKEIGENQIIQICLEDYVTAVLEYIDVENIQAQQFHLLINKMDCL
LQPLLLSFFQRLGCSITWVYAQERKEHVKSLMKSSHSNMAFICGEEGNVFELYDGHGRVYQSENVSEIDVSDLLLKTVED
MYPISLKLGNCYLLFYMHMEKELRQVWQRDMLYRIGKLLELIAKQGSTLSMMVEQTAPLYLLCDEVVCSWNEKGKIMGML
LQDMGEREIEILEGVQFKYAEKEWSYIVSDVKQPKFLVYSHAKNPLVARENMKNLIEKIRQYQKV

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=378, Percent_Identity=27.7777777777778, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI11761619, Length=395, Percent_Identity=26.5822784810127, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI31881779, Length=358, Percent_Identity=25.9776536312849, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI45447090, Length=358, Percent_Identity=25.9776536312849, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI1790224, Length=246, Percent_Identity=31.3008130081301, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788351, Length=240, Percent_Identity=32.0833333333333, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1789837, Length=370, Percent_Identity=22.1621621621622, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI133931050, Length=377, Percent_Identity=28.6472148541114, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17509979, Length=342, Percent_Identity=24.2690058479532, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17509981, Length=329, Percent_Identity=23.1003039513678, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=371, Percent_Identity=29.6495956873315, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21355443, Length=366, Percent_Identity=29.7814207650273, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24644084, Length=366, Percent_Identity=29.7814207650273, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24653912, Length=375, Percent_Identity=26.1333333333333, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 90055; Mature: 90055

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCMKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQYLSN
CCCCCEEEECCCCCEECCEECCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
TIREYFGDGSKWGVKLHYFEDSPPLGTAGSIKQAEAFLDEPFVVISGDALTDFPLTEGIV
HHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCHH
FHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKPSWNEVISNVVNTGIYIMDPS
HHHHHHHHHHHHHHHHCCCHHCCEEEECCHHHHHHHHCCCCHHHHHHHHHHCCEEEECCH
IFSYIPPKTYADFSRHIFPLLENTNALFGYKAEGYWMDIGTFEQYRQAQFDLLTKKVNVT
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHEEEEEE
IPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPYSIIGKHSTVSSYTRL
ECHHHHHHHHHCCCEEEEECCCEECCCCCCCCCEEECCCCEECCHHHHCCCCHHHHHHHH
QKSIIFANTYIGKHCELLETTVGEKTRLEDDVTLYQKSVVADCCQIGKSTVIKQGGKLWP
HHHHHEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
HKIIDHHSIIASGGVTKEEHASRWLQRSQIVGRGNIEITPQIIVKIAMAYGSLFRKGETI
HHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHCCCEE
LIGSYKNAEVQVFKKLFLHALHSVGMNTVECQEMNESPFQYTIRKLECIGGAFICFTKDQ
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHCCCEEEEEECCC
DMRIRFYGKEGRQLTYKQQKEIENLYMAENFRYVSEKEIGENQIIQICLEDYVTAVLEYI
CCEEEEECCCCCEECHHHHHHHHHHHHHHCCEECCHHHCCHHHHHHHHHHHHHHHHHHHH
DVENIQAQQFHLLINKMDCLLQPLLLSFFQRLGCSITWVYAQERKEHVKSLMKSSHSNMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEE
FICGEEGNVFELYDGHGRVYQSENVSEIDVSDLLLKTVEDMYPISLKLGNCYLLFYMHME
EEECCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEEEHHHH
KELRQVWQRDMLYRIGKLLELIAKQGSTLSMMVEQTAPLYLLCDEVVCSWNEKGKIMGML
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCEEEEEHHHHHCCCCCCHHHHHH
LQDMGEREIEILEGVQFKYAEKEWSYIVSDVKQPKFLVYSHAKNPLVARENMKNLIEKIR
HHHCCCCHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
QYQKV
HHHCC
>Mature Secondary Structure
MCMKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQYLSN
CCCCCEEEECCCCCEECCEECCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
TIREYFGDGSKWGVKLHYFEDSPPLGTAGSIKQAEAFLDEPFVVISGDALTDFPLTEGIV
HHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCHH
FHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKPSWNEVISNVVNTGIYIMDPS
HHHHHHHHHHHHHHHHCCCHHCCEEEECCHHHHHHHHCCCCHHHHHHHHHHCCEEEECCH
IFSYIPPKTYADFSRHIFPLLENTNALFGYKAEGYWMDIGTFEQYRQAQFDLLTKKVNVT
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHEEEEEE
IPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPYSIIGKHSTVSSYTRL
ECHHHHHHHHHCCCEEEEECCCEECCCCCCCCCEEECCCCEECCHHHHCCCCHHHHHHHH
QKSIIFANTYIGKHCELLETTVGEKTRLEDDVTLYQKSVVADCCQIGKSTVIKQGGKLWP
HHHHHEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
HKIIDHHSIIASGGVTKEEHASRWLQRSQIVGRGNIEITPQIIVKIAMAYGSLFRKGETI
HHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHCCCEE
LIGSYKNAEVQVFKKLFLHALHSVGMNTVECQEMNESPFQYTIRKLECIGGAFICFTKDQ
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHCCCEEEEEECCC
DMRIRFYGKEGRQLTYKQQKEIENLYMAENFRYVSEKEIGENQIIQICLEDYVTAVLEYI
CCEEEEECCCCCEECHHHHHHHHHHHHHHCCEECCHHHCCHHHHHHHHHHHHHHHHHHHH
DVENIQAQQFHLLINKMDCLLQPLLLSFFQRLGCSITWVYAQERKEHVKSLMKSSHSNMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEE
FICGEEGNVFELYDGHGRVYQSENVSEIDVSDLLLKTVEDMYPISLKLGNCYLLFYMHME
EEECCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEEEHHHH
KELRQVWQRDMLYRIGKLLELIAKQGSTLSMMVEQTAPLYLLCDEVVCSWNEKGKIMGML
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCEEEEEHHHHHCCCCCCHHHHHH
LQDMGEREIEILEGVQFKYAEKEWSYIVSDVKQPKFLVYSHAKNPLVARENMKNLIEKIR
HHHCCCCHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
QYQKV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]