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The map label for this gene is yqgN [H]

Identifier: 152976698

GI number: 152976698

Start: 3040613

End: 3041176

Strand: Reverse

Name: yqgN [H]

Synonym: Bcer98_2993

Alternate gene names: 152976698

Gene position: 3041176-3040613 (Counterclockwise)

Preceding gene: 152976699

Following gene: 152976697

Centisome position: 74.41

GC content: 35.64

Gene sequence:

>564_bases
ATGAATGAGGAGAAGATACAGCTACGTAAACGAATGTTAAAACACATGTATTCGATGACACAAGAGCAGCGTAAGGCTTT
ATCAGAACAAATTGCAGATTCTTTATATGAACAAAGAGAGTGGAAAGAGGCAGAAACAATTGGGATTACTCTTTCTATGG
ACCATGAAGTGAATACATATGTTATTATAGAAAAAGCATGGCAAGAAGGAAAAAAAGTAGTTGTACCAAAATGTAATCGA
AAGACAAGAACAATGACTTTTCGTGAAATCATGAACTGGGATCAATTAGAAACGGTATATATGAATTTGCGAGAGCCTAT
TCCTACTGTAACGAAAGAAGTAAAGGTGAATGAGATAGATCTTCTCTTTGTCCCTGGAATTGCTTATACGAGACGAGGAG
AACGTATTGGATATGGTGGCGGCTATTATGATCGTTACCTTGCTACATATGAGGGGGCAAGAGTGTCTTTAGCTTTTGAC
TTTCAAATTGTAGATGATATTCCGATAGAACCATTTGATCAGAATGTCGAAAAAATTATTACAGAAAAAGAAACAATTGT
GTAA

Upstream 100 bases:

>100_bases
TATTTTGTGCCACTATTTCGCTGTGCAGTGTGTATTTAAAATGATAAACTATCCCATAGGGATGTAATGCATGGTTTAAG
ATTAGAAGGGGGAAATAGTC

Downstream 100 bases:

>100_bases
AATACTCTGATAGAGATGAATAAGAATTGACGAGGCTTTTTCTCGTTGATTATAATGAAATATGTGAACGTTTTCTTATT
ATATTTGTATAATAAGTAGA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNEEKIQLRKRMLKHMYSMTQEQRKALSEQIADSLYEQREWKEAETIGITLSMDHEVNTYVIIEKAWQEGKKVVVPKCNR
KTRTMTFREIMNWDQLETVYMNLREPIPTVTKEVKVNEIDLLFVPGIAYTRRGERIGYGGGYYDRYLATYEGARVSLAFD
FQIVDDIPIEPFDQNVEKIITEKETIV

Sequences:

>Translated_187_residues
MNEEKIQLRKRMLKHMYSMTQEQRKALSEQIADSLYEQREWKEAETIGITLSMDHEVNTYVIIEKAWQEGKKVVVPKCNR
KTRTMTFREIMNWDQLETVYMNLREPIPTVTKEVKVNEIDLLFVPGIAYTRRGERIGYGGGYYDRYLATYEGARVSLAFD
FQIVDDIPIEPFDQNVEKIITEKETIV
>Mature_187_residues
MNEEKIQLRKRMLKHMYSMTQEQRKALSEQIADSLYEQREWKEAETIGITLSMDHEVNTYVIIEKAWQEGKKVVVPKCNR
KTRTMTFREIMNWDQLETVYMNLREPIPTVTKEVKVNEIDLLFVPGIAYTRRGERIGYGGGYYDRYLATYEGARVSLAFD
FQIVDDIPIEPFDQNVEKIITEKETIV

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=196, Percent_Identity=26.0204081632653, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1789278, Length=172, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17510857, Length=199, Percent_Identity=27.1356783919598, Blast_Score=93, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321031, Length=204, Percent_Identity=24.5098039215686, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161077430, Length=194, Percent_Identity=27.8350515463918, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 22097; Mature: 22097

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEEKIQLRKRMLKHMYSMTQEQRKALSEQIADSLYEQREWKEAETIGITLSMDHEVNTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCEE
VIIEKAWQEGKKVVVPKCNRKTRTMTFREIMNWDQLETVYMNLREPIPTVTKEVKVNEID
EEEEEHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCEEE
LLFVPGIAYTRRGERIGYGGGYYDRYLATYEGARVSLAFDFQIVDDIPIEPFDQNVEKII
EEEECCCCEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHHHH
TEKETIV
HHHHCCC
>Mature Secondary Structure
MNEEKIQLRKRMLKHMYSMTQEQRKALSEQIADSLYEQREWKEAETIGITLSMDHEVNTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCEE
VIIEKAWQEGKKVVVPKCNRKTRTMTFREIMNWDQLETVYMNLREPIPTVTKEVKVNEID
EEEEEHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCEEE
LLFVPGIAYTRRGERIGYGGGYYDRYLATYEGARVSLAFDFQIVDDIPIEPFDQNVEKII
EEEECCCCEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHHHH
TEKETIV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]