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The map label for this gene is dinB [H]

Identifier: 152976551

GI number: 152976551

Start: 2914485

End: 2915723

Strand: Reverse

Name: dinB [H]

Synonym: Bcer98_2840

Alternate gene names: 152976551

Gene position: 2915723-2914485 (Counterclockwise)

Preceding gene: 152976552

Following gene: 152976548

Centisome position: 71.34

GC content: 37.29

Gene sequence:

>1239_bases
ATGCGAGAAATGTATCCGAAAAATGGACATGTTATTTTACATGTTGACATGAATTGTTTTTTCGCATCGGTTGAAATTGC
ACATGATCCATCGTTAAAAGGAAAACCGCTAGCAATTGCAGGAAATGAAAAAGAGCGAAAAGGAATTATTGTGACATGCA
GCTATGAAGCGAGAGAATACGGGATACGTACAACGATGCAACTTTGGGAAGCAAAGAAGTTATGTCCCCATTTAATTGTG
AAGCAGCCGAATTTTACATTATATCGAGAAGCTTCTTTTCAGATGTTTCAAATTCTCTCTCGTTTCACAGAGAAAATCCA
ACCGGTATCGATAGATGAAGGATATTTAGACATTACAGATTGCTATGCGCTTGGTACGCCAATTGAAATTGCAAAAATGA
TTCAACAGACATTAGTAACAGAATTGCAACTTCCATGTAGCATCGGGATAGCACCAAATCTCTTTCTTGCGAAAACAGCT
TCTGATATGCAAAAGCCGCTCGGTATTACAGTGCTGCGCAAGCGAGATATTCCGTACATGCTTTGGCCACGTTCCGTTGA
AAGTATGCATGGAATTGGGAAGAAAACAGCAGAGAAATTAAATGAAATTCATATATATACGATTGAACAGTTAGCAAAGG
GAGACGAACATATTATTCGTGCGAAGCTTGGAAAGCATGGTGTTGACTTACAAAAACGAGCAAAAGGTATCGATGATCGA
AAGGTTGATCCAAATCAAATAGGGCAACATAAAAGCGTTGGAAATTCAATGACTTTTTCAAAGGATATGGATGAAGAGAA
GGAATTGCTTGATATGCTGAAGAAATTATCAAAATCGGTAAGCAGTAGATTACAAAAACGTACGCTCGTTAGCTACAATA
TTCAAATTATAATTAAATATTATGATAGGCGTACAATCACGCGAAGTAAACAATTAAAAAATGCAGTTTGGGAAGAGCGC
GATATATTTCAAGCAGCTTCTCGTTTATGGAAACAGCATTGGAATGGTGATTCTATTCGTTTACTCGGTGTTACAGCGAC
TGAACTAGAATGGAAAACGGAATCGGTCAAGCAATTAGATTTATTCTCATTTGAGCAAGATGCAAAAGAAGAGCCGTTAT
TAGCCGTTATCGAACAAATTAATGATAAGTATGGAACGCCGCTGTTACAACGAGGGAGTCAATTGTTACGCAAACAAGAG
AAATCGTTCCAACAAAGATTAGAAAATAAATTTCTATAG

Upstream 100 bases:

>100_bases
TAAGAGATAGAAAAAAGAACAAATTTTTACGAGACCATACCACTATTGTAAATAAATCTGATATAATAAAAGAACAAATG
TTCTTTGTGAGGTGGATAAT

Downstream 100 bases:

>100_bases
AAAGTGCCATGATTACATATAAGCATCATGACACTTTTTTCTTTAGCGAGAGTTTGGAAATACTCTTCGAACCGTTTCAT
TAAATTCCTCAATTAGTCCT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MREMYPKNGHVILHVDMNCFFASVEIAHDPSLKGKPLAIAGNEKERKGIIVTCSYEAREYGIRTTMQLWEAKKLCPHLIV
KQPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGTPIEIAKMIQQTLVTELQLPCSIGIAPNLFLAKTA
SDMQKPLGITVLRKRDIPYMLWPRSVESMHGIGKKTAEKLNEIHIYTIEQLAKGDEHIIRAKLGKHGVDLQKRAKGIDDR
KVDPNQIGQHKSVGNSMTFSKDMDEEKELLDMLKKLSKSVSSRLQKRTLVSYNIQIIIKYYDRRTITRSKQLKNAVWEER
DIFQAASRLWKQHWNGDSIRLLGVTATELEWKTESVKQLDLFSFEQDAKEEPLLAVIEQINDKYGTPLLQRGSQLLRKQE
KSFQQRLENKFL

Sequences:

>Translated_412_residues
MREMYPKNGHVILHVDMNCFFASVEIAHDPSLKGKPLAIAGNEKERKGIIVTCSYEAREYGIRTTMQLWEAKKLCPHLIV
KQPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGTPIEIAKMIQQTLVTELQLPCSIGIAPNLFLAKTA
SDMQKPLGITVLRKRDIPYMLWPRSVESMHGIGKKTAEKLNEIHIYTIEQLAKGDEHIIRAKLGKHGVDLQKRAKGIDDR
KVDPNQIGQHKSVGNSMTFSKDMDEEKELLDMLKKLSKSVSSRLQKRTLVSYNIQIIIKYYDRRTITRSKQLKNAVWEER
DIFQAASRLWKQHWNGDSIRLLGVTATELEWKTESVKQLDLFSFEQDAKEEPLLAVIEQINDKYGTPLLQRGSQLLRKQE
KSFQQRLENKFL
>Mature_412_residues
MREMYPKNGHVILHVDMNCFFASVEIAHDPSLKGKPLAIAGNEKERKGIIVTCSYEAREYGIRTTMQLWEAKKLCPHLIV
KQPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGTPIEIAKMIQQTLVTELQLPCSIGIAPNLFLAKTA
SDMQKPLGITVLRKRDIPYMLWPRSVESMHGIGKKTAEKLNEIHIYTIEQLAKGDEHIIRAKLGKHGVDLQKRAKGIDDR
KVDPNQIGQHKSVGNSMTFSKDMDEEKELLDMLKKLSKSVSSRLQKRTLVSYNIQIIIKYYDRRTITRSKQLKNAVWEER
DIFQAASRLWKQHWNGDSIRLLGVTATELEWKTESVKQLDLFSFEQDAKEEPLLAVIEQINDKYGTPLLQRGSQLLRKQE
KSFQQRLENKFL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=337, Percent_Identity=28.486646884273, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7706681, Length=338, Percent_Identity=28.4023668639053, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI154350220, Length=329, Percent_Identity=27.0516717325228, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5729982, Length=117, Percent_Identity=42.7350427350427, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7705344, Length=111, Percent_Identity=38.7387387387387, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=36.676217765043, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787432, Length=413, Percent_Identity=24.2130750605327, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17537959, Length=196, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=121, Percent_Identity=33.8842975206612, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=112, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=340, Percent_Identity=29.1176470588235, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355641, Length=348, Percent_Identity=27.8735632183908, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644984, Length=348, Percent_Identity=27.8735632183908, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668444, Length=124, Percent_Identity=38.7096774193548, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47552; Mature: 47552

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREMYPKNGHVILHVDMNCFFASVEIAHDPSLKGKPLAIAGNEKERKGIIVTCSYEAREY
CCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECHHHHH
GIRTTMQLWEAKKLCPHLIVKQPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITD
HHHHHHHHHHHHHHCHHHEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEHHH
CYALGTPIEIAKMIQQTLVTELQLPCSIGIAPNLFLAKTASDMQKPLGITVLRKRDIPYM
HHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHHEECCHHHHHCCCCEEEEEECCCCEE
LWPRSVESMHGIGKKTAEKLNEIHIYTIEQLAKGDEHIIRAKLGKHGVDLQKRAKGIDDR
ECCCHHHHHHCCCHHHHHHHHCEEEEEHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCCC
KVDPNQIGQHKSVGNSMTFSKDMDEEKELLDMLKKLSKSVSSRLQKRTLVSYNIQIIIKY
CCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEEEEE
YDRRTITRSKQLKNAVWEERDIFQAASRLWKQHWNGDSIRLLGVTATELEWKTESVKQLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHH
LFSFEQDAKEEPLLAVIEQINDKYGTPLLQRGSQLLRKQEKSFQQRLENKFL
HHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MREMYPKNGHVILHVDMNCFFASVEIAHDPSLKGKPLAIAGNEKERKGIIVTCSYEAREY
CCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECHHHHH
GIRTTMQLWEAKKLCPHLIVKQPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITD
HHHHHHHHHHHHHHCHHHEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEHHH
CYALGTPIEIAKMIQQTLVTELQLPCSIGIAPNLFLAKTASDMQKPLGITVLRKRDIPYM
HHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHHEECCHHHHHCCCCEEEEEECCCCEE
LWPRSVESMHGIGKKTAEKLNEIHIYTIEQLAKGDEHIIRAKLGKHGVDLQKRAKGIDDR
ECCCHHHHHHCCCHHHHHHHHCEEEEEHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCCC
KVDPNQIGQHKSVGNSMTFSKDMDEEKELLDMLKKLSKSVSSRLQKRTLVSYNIQIIIKY
CCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEEEEE
YDRRTITRSKQLKNAVWEERDIFQAASRLWKQHWNGDSIRLLGVTATELEWKTESVKQLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHH
LFSFEQDAKEEPLLAVIEQINDKYGTPLLQRGSQLLRKQEKSFQQRLENKFL
HHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]