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The map label for this gene is rnz

Identifier: 152976548

GI number: 152976548

Start: 2912316

End: 2913239

Strand: Reverse

Name: rnz

Synonym: Bcer98_2837

Alternate gene names: 152976548

Gene position: 2913239-2912316 (Counterclockwise)

Preceding gene: 152976551

Following gene: 152976547

Centisome position: 71.28

GC content: 39.39

Gene sequence:

>924_bases
GTGGAATTTGTGTTTTTAGGAACTGGTGCAGGTGTTCCTTCAAAAGGAAGAAATGTTTCAGCTATCGCTTTGCAGTTATT
GGAAGAAAGGGGAGGGACATGGCTATTTGATTGTGGTGAAGCAACGCAACATCAAATTTTACATACATCTGTACGTCCAC
GTCGGATTGAAAAAATATTTATTACGCATTTACATGGCGATCATATTTTTGGATTACCAGGTTTATTAGGAAGTCGTTCT
TTTCAAGGAGGAACAACGCCGTTAACGGTATATGGCCCAAAAGGAATTGAACAGTTTATTGAAGTGGCTTTATCCGTGAG
TACAACACATGTGAAATACCCGCTTGAAATTGTAGAAATTACTGAAGAGGGTATTGTCTTTGAAGACAAACAATTTTATG
TCGAAACAAAGAGACTGTCACATGGGATTGAATGTTTTGGATACCGAATTGTTGAGAAAGATATACAAGGCCCTCTTCTT
GTAGAGAAGTTACGAGAAGCTAATGTGAAACCAGGTCCGATTTTTAAACGTTTAAAAGATGGAGAGATTGTTGAATTAGA
AGACGGAAGAGTGTTAGATGGGAAGGACTTTATTGGGCCTCCGCAAAAAGGAAGAATTATTACCATTTTAGGAGATACTC
GTTATTGTGATGCGAGTAGAATTCTTGCCCAAGATGCTGATGTACTTGTACATGAGGCGACATTTGCAGCAGCGGATCAA
ACCCAGGCTCATGATTATTTTCATTCCACAACTGAGCAGGCGGCACGCATTGCCCTAGAAGCAAACGTGAAGCGTTTAAT
ATTGACACATATTAGTTCACGTTATCAAGGCGATATGTATAAGGAGTTGTTGCGAGAAGCAAAAGCTGTATTTGCCCATA
CAGAAATAGCGATGGACTTGAAGTCATTTCCAGTAGAAAGATAA

Upstream 100 bases:

>100_bases
ATAGATGTCTAGATAGCTTGTTAAGGAGATTACATTTGCCATTTTACATAACATTCCGTAAGATGAAAGATAGACTATAT
AAAGAGCTGGAGGAAAGAAA

Downstream 100 bases:

>100_bases
CATTTTTCAAACAATGGCAATAAAAAATTGCCATTGTTTCATTTTGAAAAAATTTTTTTAATCTATATATTGGTAAAGCT
GTTATCATTAAATAGTTTTA

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEFVFLGTGAGVPSKGRNVSAIALQLLEERGGTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRS
FQGGTTPLTVYGPKGIEQFIEVALSVSTTHVKYPLEIVEITEEGIVFEDKQFYVETKRLSHGIECFGYRIVEKDIQGPLL
VEKLREANVKPGPIFKRLKDGEIVELEDGRVLDGKDFIGPPQKGRIITILGDTRYCDASRILAQDADVLVHEATFAAADQ
TQAHDYFHSTTEQAARIALEANVKRLILTHISSRYQGDMYKELLREAKAVFAHTEIAMDLKSFPVER

Sequences:

>Translated_307_residues
MEFVFLGTGAGVPSKGRNVSAIALQLLEERGGTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRS
FQGGTTPLTVYGPKGIEQFIEVALSVSTTHVKYPLEIVEITEEGIVFEDKQFYVETKRLSHGIECFGYRIVEKDIQGPLL
VEKLREANVKPGPIFKRLKDGEIVELEDGRVLDGKDFIGPPQKGRIITILGDTRYCDASRILAQDADVLVHEATFAAADQ
TQAHDYFHSTTEQAARIALEANVKRLILTHISSRYQGDMYKELLREAKAVFAHTEIAMDLKSFPVER
>Mature_307_residues
MEFVFLGTGAGVPSKGRNVSAIALQLLEERGGTWLFDCGEATQHQILHTSVRPRRIEKIFITHLHGDHIFGLPGLLGSRS
FQGGTTPLTVYGPKGIEQFIEVALSVSTTHVKYPLEIVEITEEGIVFEDKQFYVETKRLSHGIECFGYRIVEKDIQGPLL
VEKLREANVKPGPIFKRLKDGEIVELEDGRVLDGKDFIGPPQKGRIITILGDTRYCDASRILAQDADVLVHEATFAAADQ
TQAHDYFHSTTEQAARIALEANVKRLILTHISSRYQGDMYKELLREAKAVFAHTEIAMDLKSFPVER

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=351, Percent_Identity=36.7521367521368, Blast_Score=207, Evalue=8e-54,
Organism=Escherichia coli, GI87082078, Length=306, Percent_Identity=50.6535947712418, Blast_Score=313, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24652403, Length=107, Percent_Identity=36.4485981308411, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_BACCN (A7GSG2)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376065.1
- ProteinModelPortal:   A7GSG2
- SMR:   A7GSG2
- STRING:   A7GSG2
- EnsemblBacteria:   EBBACT00000037277
- GeneID:   5343522
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2837
- eggNOG:   COG1234
- GeneTree:   EBGT00050000001790
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- ProtClustDB:   PRK00055
- BioCyc:   BCER315749:BCER98_2837-MONOMER
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- SMART:   SM00849
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 34312; Mature: 34312

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFVFLGTGAGVPSKGRNVSAIALQLLEERGGTWLFDCGEATQHQILHTSVRPRRIEKIF
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCHHEEEEE
ITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIEQFIEVALSVSTTHVKYPLEIVEI
EEEECCCEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCEEEEECCEEEEEE
TEEGIVFEDKQFYVETKRLSHGIECFGYRIVEKDIQGPLLVEKLREANVKPGPIFKRLKD
ECCCCEEECCHHEEEHHHHHCCHHHHEEEEEHHCCCCHHHHHHHHHCCCCCCHHHHHCCC
GEIVELEDGRVLDGKDFIGPPQKGRIITILGDTRYCDASRILAQDADVLVHEATFAAADQ
CCEEEECCCEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCEEEEHHHHHCCCC
TQAHDYFHSTTEQAARIALEANVKRLILTHISSRYQGDMYKELLREAKAVFAHTEIAMDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KSFPVER
HHCCCCC
>Mature Secondary Structure
MEFVFLGTGAGVPSKGRNVSAIALQLLEERGGTWLFDCGEATQHQILHTSVRPRRIEKIF
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCHHEEEEE
ITHLHGDHIFGLPGLLGSRSFQGGTTPLTVYGPKGIEQFIEVALSVSTTHVKYPLEIVEI
EEEECCCEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCEEEEECCEEEEEE
TEEGIVFEDKQFYVETKRLSHGIECFGYRIVEKDIQGPLLVEKLREANVKPGPIFKRLKD
ECCCCEEECCHHEEEHHHHHCCHHHHEEEEEHHCCCCHHHHHHHHHCCCCCCHHHHHCCC
GEIVELEDGRVLDGKDFIGPPQKGRIITILGDTRYCDASRILAQDADVLVHEATFAAADQ
CCEEEECCCEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCEEEEHHHHHCCCC
TQAHDYFHSTTEQAARIALEANVKRLILTHISSRYQGDMYKELLREAKAVFAHTEIAMDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KSFPVER
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA