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The map label for this gene is argD [H]

Identifier: 152976537

GI number: 152976537

Start: 2901860

End: 2903020

Strand: Reverse

Name: argD [H]

Synonym: Bcer98_2826

Alternate gene names: 152976537

Gene position: 2903020-2901860 (Counterclockwise)

Preceding gene: 152976538

Following gene: 152976536

Centisome position: 71.03

GC content: 37.47

Gene sequence:

>1161_bases
ATGAATAGTTTGATTTTTCCGACATATATAAGGCGTGAAATAGAAATAGTAAAAGGAATTGGTACGAAAGTAATGGACAG
AAGCGGAAAAGAATACTTAGATTTTACGTCTGGAATTGCCGTCTGCAATTTAGGACATTGTCACCCAAATCTTATCGAAA
ATGTAACGAAACAACTACACGAAATGTGGCACATATCTAATCTTTTCTCGCATTCTATTCAAGAAGATGTAGCAAGATTG
TTAACGGAAGATAGAGAATTAAAATATGTATTTTTCTGTAATAGCGGTGCTGAGGCGAATGAAGCAGCATTGAAAATTGC
GCGTAAATATACAGGGAAATCTCTTGTTTTAACATTTCAGCAGTCTTTTCATGGTCGAACATTTGGAACGATGAGTGCAA
CAGGACAAGAAAAGGTAAAAGAAGGATTTGGACCACTTCTTCCATCATTTTTACATCTTCCTTTCAATGATATAGCTGCT
CTTAGAGAAGCGATGAATCAAGATGTAGCCGCAATTTTGGTTGAAATTGTTCAAGGAGAAGGTGGTGTTTTACTGGCTCA
TTGCGACTTCTTGCAAGAAATTGAAAAGTTATGTAAAGAATATGGAGCGCTTTGTATTATTGATGAGGTACAGACGGGAA
TAGGGAGAACAGGTACATTGTTCGCTTATGAACAGACAGGTCTATCTCCTGATATTGTAACAGTGGCAAAAGCATTAGGA
AATGGAATTCCAGTTGGGGCCATGATAGGAAGAGAAGAGTTAGCGGTGGCTTTTACAGCAGGAACACATGGTTCAACATT
TGGCGGGAATTATATTGCAATGGCTGCTACCAAAGCAGTATTACAACTTGCAAAACAACCATCATTTTTACAAGAGGTCA
AAGAAAAAGGCGCGTATTTCTTGCAAAGGTTGAAACAAGAGTTGTTACACGTTGAAGACATTTGTGCTATTCGCGGGCGA
GGACTTATGGTTGGGACTTCTTGTAAAAAGAATGTCTCATCTTATATTGAGCAATTAGAAAAAGAAGGACTTCTTGCACT
GCAAGCTGGTTCCAATGTGTTACGGCTATTACCACCACTCATTGTTACAAAGGAAGAGTTAGAACAAGCCATATACATGA
TCAAAAAAGTAATCTGTACAAAAATATTACCATCTATATAA

Upstream 100 bases:

>100_bases
ATGGGGATTCAAAGTGTAAGCATTGTCAATGGTACAAAAAATTTTATTGGATTAACCGGTGAATGGATTGGAACAACAGT
AACAAGGGGGAGGTTGCAGT

Downstream 100 bases:

>100_bases
GGGGGAAATACGATGTCAATTGTACAAGTGCCGAAATTACAAACGAAACATGTATTAACTTTGGAAGAATTAACGCAAGA
AGAAATCATTTCTGTAATTA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNSLIFPTYIRREIEIVKGIGTKVMDRSGKEYLDFTSGIAVCNLGHCHPNLIENVTKQLHEMWHISNLFSHSIQEDVARL
LTEDRELKYVFFCNSGAEANEAALKIARKYTGKSLVLTFQQSFHGRTFGTMSATGQEKVKEGFGPLLPSFLHLPFNDIAA
LREAMNQDVAAILVEIVQGEGGVLLAHCDFLQEIEKLCKEYGALCIIDEVQTGIGRTGTLFAYEQTGLSPDIVTVAKALG
NGIPVGAMIGREELAVAFTAGTHGSTFGGNYIAMAATKAVLQLAKQPSFLQEVKEKGAYFLQRLKQELLHVEDICAIRGR
GLMVGTSCKKNVSSYIEQLEKEGLLALQAGSNVLRLLPPLIVTKEELEQAIYMIKKVICTKILPSI

Sequences:

>Translated_386_residues
MNSLIFPTYIRREIEIVKGIGTKVMDRSGKEYLDFTSGIAVCNLGHCHPNLIENVTKQLHEMWHISNLFSHSIQEDVARL
LTEDRELKYVFFCNSGAEANEAALKIARKYTGKSLVLTFQQSFHGRTFGTMSATGQEKVKEGFGPLLPSFLHLPFNDIAA
LREAMNQDVAAILVEIVQGEGGVLLAHCDFLQEIEKLCKEYGALCIIDEVQTGIGRTGTLFAYEQTGLSPDIVTVAKALG
NGIPVGAMIGREELAVAFTAGTHGSTFGGNYIAMAATKAVLQLAKQPSFLQEVKEKGAYFLQRLKQELLHVEDICAIRGR
GLMVGTSCKKNVSSYIEQLEKEGLLALQAGSNVLRLLPPLIVTKEELEQAIYMIKKVICTKILPSI
>Mature_386_residues
MNSLIFPTYIRREIEIVKGIGTKVMDRSGKEYLDFTSGIAVCNLGHCHPNLIENVTKQLHEMWHISNLFSHSIQEDVARL
LTEDRELKYVFFCNSGAEANEAALKIARKYTGKSLVLTFQQSFHGRTFGTMSATGQEKVKEGFGPLLPSFLHLPFNDIAA
LREAMNQDVAAILVEIVQGEGGVLLAHCDFLQEIEKLCKEYGALCIIDEVQTGIGRTGTLFAYEQTGLSPDIVTVAKALG
NGIPVGAMIGREELAVAFTAGTHGSTFGGNYIAMAATKAVLQLAKQPSFLQEVKEKGAYFLQRLKQELLHVEDICAIRGR
GLMVGTSCKKNVSSYIEQLEKEGLLALQAGSNVLRLLPPLIVTKEELEQAIYMIKKVICTKILPSI

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=31.331592689295, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=29.7921478060046, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.2225913621262, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=28.4313725490196, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=25.1798561151079, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=27.7777777777778, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=27.4509803921569, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=39.2857142857143, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI1788044, Length=377, Percent_Identity=41.3793103448276, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=36.71875, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789016, Length=414, Percent_Identity=33.8164251207729, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787560, Length=390, Percent_Identity=35.1282051282051, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1786991, Length=395, Percent_Identity=27.3417721518987, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786349, Length=316, Percent_Identity=31.9620253164557, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=387, Percent_Identity=32.5581395348837, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=30.5555555555556, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI25144274, Length=375, Percent_Identity=30.4, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=404, Percent_Identity=28.960396039604, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17541228, Length=444, Percent_Identity=25.4504504504505, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71981843, Length=190, Percent_Identity=28.4210526315789, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=36.4795918367347, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=33.7595907928389, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=406, Percent_Identity=24.8768472906404, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=377, Percent_Identity=24.1379310344828, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=30.5483028720627, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI28574759, Length=431, Percent_Identity=30.1624129930394, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI161085790, Length=418, Percent_Identity=30.3827751196172, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI21356575, Length=409, Percent_Identity=30.5623471882641, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=25.1173708920188, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=25.1173708920188, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=25.1173708920188, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42409; Mature: 42409

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLIFPTYIRREIEIVKGIGTKVMDRSGKEYLDFTSGIAVCNLGHCHPNLIENVTKQLH
CCCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCHHEEECCCCCHHHHHHHHHHHH
EMWHISNLFSHSIQEDVARLLTEDRELKYVFFCNSGAEANEAALKIARKYTGKSLVLTFQ
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEH
QSFHGRTFGTMSATGQEKVKEGFGPLLPSFLHLPFNDIAALREAMNQDVAAILVEIVQGE
HHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCC
GGVLLAHCDFLQEIEKLCKEYGALCIIDEVQTGIGRTGTLFAYEQTGLSPDIVTVAKALG
CCEEEEHHHHHHHHHHHHHHHCCEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHC
NGIPVGAMIGREELAVAFTAGTHGSTFGGNYIAMAATKAVLQLAKQPSFLQEVKEKGAYF
CCCCCHHHCCHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQRLKQELLHVEDICAIRGRGLMVGTSCKKNVSSYIEQLEKEGLLALQAGSNVLRLLPPL
HHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHCHH
IVTKEELEQAIYMIKKVICTKILPSI
HCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSLIFPTYIRREIEIVKGIGTKVMDRSGKEYLDFTSGIAVCNLGHCHPNLIENVTKQLH
CCCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCHHEEECCCCCHHHHHHHHHHHH
EMWHISNLFSHSIQEDVARLLTEDRELKYVFFCNSGAEANEAALKIARKYTGKSLVLTFQ
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEH
QSFHGRTFGTMSATGQEKVKEGFGPLLPSFLHLPFNDIAALREAMNQDVAAILVEIVQGE
HHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCC
GGVLLAHCDFLQEIEKLCKEYGALCIIDEVQTGIGRTGTLFAYEQTGLSPDIVTVAKALG
CCEEEEHHHHHHHHHHHHHHHCCEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHC
NGIPVGAMIGREELAVAFTAGTHGSTFGGNYIAMAATKAVLQLAKQPSFLQEVKEKGAYF
CCCCCHHHCCHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQRLKQELLHVEDICAIRGRGLMVGTSCKKNVSSYIEQLEKEGLLALQAGSNVLRLLPPL
HHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHCHH
IVTKEELEQAIYMIKKVICTKILPSI
HCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]